Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr22 | 30057272 | . | C | A | CCDS13861.1:NM_000268.3:c.754Ccc>Acc_NP_000259.1:p.252P>T | Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6cds | 1 | P35240 | 99.71 | 0.0 |
X-RAY |
2018-07-18 | PRO | A:252 | A:252 | 33.0 | 0.228 | -75.4 | 152.4 | 33.0 | 0.228 | 0.0 |
PO4 HOH |
7.231 3.063 |
CD O |
O4 O |
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| PRO | B:252 | B:252 | 32.0 | 0.221 | -74.3 | 152.5 | NA | NA | NA | ||||||||||||||
| 7lwh | 1 | P35240 | 99.41 | 0.0 |
X-RAY |
2021-08-11 | PRO | A:252 | A:252 | 38.0 | 0.262 | -61.6 | 148.1 | 38.0 | 0.262 | 0.0 |
IMD GOL HOH |
7.898 7.259 2.646 |
CG CG O |
C2 O3 O |
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| 1isn | 1 | P46662 | 99.38 | 0.0 |
X-RAY |
2002-04-03 | PRO | A:235 | A:252 | 38.0 | 0.262 | -70.0 | 145.7 | 38.0 | 0.262 | 0.0 | |||||||
| 4zrj | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2015-06-17 | PRO | A:252 | A:252 | 40.0 | 0.276 | -73.9 | 154.7 | 21.0 | 0.145 | 0.131 |
B:P35240:0.131 |
GOL HOH |
3.574 4.102 |
CD CA |
C3 O |
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| 4zri | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2015-06-17 | PRO | A:256 | A:252 | 36.0 | 0.248 | -58.3 | 149.4 | 36.0 | 0.248 | 0.0 |
HOH |
4.646 |
CG |
O |
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| PRO | B:256 | B:252 | 34.0 | 0.234 | -63.7 | 158.9 | NA | NA | NA | ||||||||||||||
| 4zrk | 1 | P46662 | 99.38 | 0.0 |
X-RAY |
2015-06-17 | PRO | A:256 | A:252 | 39.0 | 0.269 | -68.8 | 149.5 | 39.0 | 0.269 | 0.0 | |||||||
| PRO | B:256 | B:252 | 39.0 | 0.269 | -71.0 | 150.0 | NA | NA | NA | ||||||||||||||
| PRO | C:256 | C:252 | 41.0 | 0.283 | -68.5 | 147.4 | NA | NA | NA | ||||||||||||||
| PRO | D:256 | D:252 | 36.0 | 0.248 | -70.6 | 151.8 | NA | NA | NA | ||||||||||||||
| 1h4r | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2002-01-16 | PRO | A:253 | A:252 | 31.0 | 0.214 | -72.8 | 148.0 | 31.0 | 0.214 | 0.0 |
SO4 HOH |
4.091 3.854 |
CG CD |
O2 O |
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| PRO | B:253 | B:252 | 33.0 | 0.228 | -75.8 | 149.9 | 33.0 | 0.228 | 0.0 |
HOH |
3.782 |
CD |
O |
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| 4p7i | 1 | P46662 | 99.36 | 0.0 |
X-RAY |
2014-04-09 | PRO | A:256 | A:252 | 36.0 | 0.248 | -73.4 | 139.8 | 36.0 | 0.248 | 0.0 |
HOH |
4.217 |
CA |
O |
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| PRO | B:256 | B:252 | 45.0 | 0.31 | -75.1 | 148.9 | NA | NA | NA | ||||||||||||||
| 3u8z | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2011-11-02 | PRO | A:240 | A:252 | 40.0 | 0.276 | -66.3 | 147.8 | 40.0 | 0.276 | 0.0 |
HOH |
2.976 |
O |
O |
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| PRO | B:240 | B:252 | 39.0 | 0.269 | -66.7 | 147.8 | NA | NA | NA | ||||||||||||||
| PRO | C:240 | C:252 | 39.0 | 0.269 | -72.5 | 144.9 | 39.0 | 0.269 | 0.0 |
HOH |
4.021 |
CD |
O |
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| PRO | D:240 | D:252 | 41.0 | 0.283 | -66.0 | 148.3 | NA | NA | NA | ||||||||||||||
| 3wa0 | 1 | P46662 | 99.32 | 0.0 |
X-RAY |
2014-05-28 | PRO | A:239 | A:252 | 39.0 | 0.269 | -71.1 | 145.5 | 39.0 | 0.269 | 0.0 |
HOH |
3.746 |
CD |
O |
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| PRO | B:239 | B:252 | 39.0 | 0.269 | -71.5 | 143.6 | NA | NA | NA | ||||||||||||||
| PRO | C:239 | C:252 | 35.0 | 0.241 | -66.4 | 152.0 | NA | NA | NA | ||||||||||||||
| PRO | D:239 | D:252 | 36.0 | 0.248 | -71.4 | 145.7 | NA | NA | NA | ||||||||||||||
| PRO | E:239 | E:252 | 40.0 | 0.276 | -73.8 | 145.5 | NA | NA | NA | ||||||||||||||
| PRO | F:239 | F:252 | 36.0 | 0.248 | -67.2 | 140.4 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p35240-f1 | 1 | P35240 | 100.0 | 0.0 | PRO | A:252 | A:252 | 8.0 | 0.055 | -68.6 | 147.1 | ||