Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30057292 . G A CCDS13861.1:NM_000268.3:c.774tgG>tgA_NP_000259.1:p.258W>* Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 TRP A:258 A:258 5.0 0.02 G -53.3 -30.9 5.0 0.02 0.0 HOH
 6.921
 NE1
 O
TRP B:258 B:258 6.0 0.024 G -52.4 -31.7 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 TRP A:258 A:258 1.0 0.004 G -52.0 -41.5 1.0 0.004 0.0 IMD
IMD
GOL
HOH
 9.235
4.077
7.912
2.998
 NE1
CZ3
N
O
 N3
N1
O3
O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 TRP A:241 A:258 1.0 0.004 T -58.8 -38.9 1.0 0.004 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TRP A:258 A:258 0.0 0.0 G -62.5 -30.0 0.0 0.0 0.0 GOL
GOL
HOH
 9.672
9.059
6.980
 NE1
NE1
CZ3
 O1
O1
O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 TRP A:262 A:258 5.0 0.02 G -48.5 -49.1 5.0 0.02 0.0
TRP B:262 B:258 4.0 0.016 G -58.6 -49.3 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 TRP A:262 A:258 3.0 0.012 G -59.4 -26.7 3.0 0.012 0.0 HOH
 7.136
 NE1
 O
TRP B:262 B:258 3.0 0.012 G -62.0 -26.4 NA NA NA
TRP C:262 C:258 2.0 0.008 G -62.0 -30.5 NA NA NA
TRP D:262 D:258 1.0 0.004 G -61.1 -28.5 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 TRP A:259 A:258 2.0 0.008 G -59.3 -32.2 2.0 0.008 0.0 SO4
HOH
 8.544
2.856
 NE1
O
 O1
O
TRP B:259 B:258 2.0 0.008 G -57.6 -37.5 2.0 0.008 0.0 HOH
 3.144
 O
 O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 TRP A:262 A:258 5.0 0.02 G -59.3 -32.1 1.0 0.004 0.016 C:Q9Y4B6:0.016
 HOH
 4.724
 CD1
 O
TRP B:262 B:258 9.0 0.035 G -56.9 -41.7 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 TRP A:246 A:258 3.0 0.012 G -56.5 -35.4 1.0 0.004 0.008 C:P35240:0.008
 HOH
 3.741
 O
 O
TRP B:246 B:258 3.0 0.012 G -56.0 -35.3 NA NA NA
TRP C:246 C:258 3.0 0.012 G -56.1 -35.0 1.0 0.004 0.008 A:P35240:0.008
 HOH
 4.902
 O
 O
TRP D:246 D:258 2.0 0.008 G -56.6 -34.3 NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 TRP A:245 A:258 5.0 0.02 G -56.6 -42.4 1.0 0.004 0.016 G:Q9Y4B6:0.016
 HOH
 6.964
 NE1
 O
TRP B:245 B:258 5.0 0.02 G -50.5 -43.0 NA NA NA
TRP C:245 C:258 4.0 0.016 G -62.1 -33.4 NA NA NA
TRP D:245 D:258 5.0 0.02 G -58.3 -40.7 NA NA NA
TRP E:245 E:258 4.0 0.016 G -60.2 -39.4 NA NA NA
TRP F:245 F:258 3.0 0.012 G -56.4 -40.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 TRP A:258 A:258 1.0 0.004 G -59.7 -33.0