Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr22 | 30057302 | . | C | A | CCDS13861.1:NM_000268.3:c.784Cga>Aga_NP_000259.1:p.262R>R | Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6cds | 1 | P35240 | 99.71 | 0.0 |
X-RAY |
2018-07-18 | ARG | A:262 | A:262 | 125.0 | 0.556 | E | -72.8 | -49.5 | 125.0 | 0.556 | 0.0 |
HOH |
6.227 |
N |
O |
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| ARG | B:262 | B:262 | 136.0 | 0.604 | E | -73.0 | -49.7 | NA | NA | NA | |||||||||||||
| 7lwh | 1 | P35240 | 99.41 | 0.0 |
X-RAY |
2021-08-11 | ARG | A:262 | A:262 | 143.0 | 0.636 | E | -76.9 | -46.7 | 143.0 | 0.636 | 0.0 |
IMD HOH |
6.019 2.812 |
O O |
C2 O |
||
| 1isn | 1 | P46662 | 99.38 | 0.0 |
X-RAY |
2002-04-03 | ARG | A:245 | A:262 | 58.0 | NA | E | -106.0 | -49.4 | 58.0 | NA | NA | ||||||
| 4zrj | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2015-06-17 | ARG | A:262 | A:262 | 48.0 | NA | E | -94.7 | -45.9 | 48.0 | NA | NA |
HOH |
6.030 |
O |
O |
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| 4zri | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2015-06-17 | ARG | A:266 | A:262 | 55.0 | NA | E | -67.4 | -52.9 | 55.0 | NA | NA | ||||||
| ARG | B:266 | B:262 | 63.0 | NA | E | -65.1 | -62.8 | NA | NA | NA | |||||||||||||
| 4zrk | 1 | P46662 | 99.38 | 0.0 |
X-RAY |
2015-06-17 | ARG | A:266 | A:262 | 58.0 | NA | E | -87.1 | -47.7 | 58.0 | NA | NA |
HOH |
6.144 |
O |
O |
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| ARG | B:266 | B:262 | 45.0 | NA | E | -86.8 | -47.0 | NA | NA | NA | |||||||||||||
| ARG | C:266 | C:262 | 159.0 | 0.707 | E | -85.7 | -46.4 | NA | NA | NA | |||||||||||||
| ARG | D:266 | D:262 | 152.0 | 0.676 | E | -86.9 | -43.2 | NA | NA | NA | |||||||||||||
| 1h4r | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2002-01-16 | ARG | A:263 | A:262 | 170.0 | 0.756 | E | -77.0 | -54.9 | 170.0 | 0.756 | 0.0 |
HOH |
2.322 |
O |
O |
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| ARG | B:263 | B:262 | 161.0 | 0.716 | E | -79.2 | -45.0 | 161.0 | 0.716 | 0.0 |
HOH |
2.787 |
O |
O |
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| 4p7i | 1 | P46662 | 99.36 | 0.0 |
X-RAY |
2014-04-09 | ARG | A:266 | A:262 | 98.0 | 0.436 | E | -77.3 | -45.9 | 73.0 | 0.324 | 0.112 |
C:Q9Y4B6:0.111 |
|||||
| ARG | B:266 | B:262 | 90.0 | 0.4 | E | -64.1 | -58.8 | NA | NA | NA | |||||||||||||
| 3u8z | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2011-11-02 | ARG | A:250 | A:262 | 146.0 | 0.649 | E | -69.0 | -49.6 | 130.0 | 0.578 | 0.071 |
C:P35240:0.071 |
HOH |
3.058 |
O |
O |
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| ARG | B:250 | B:262 | 153.0 | 0.68 | E | -68.7 | -50.3 | NA | NA | NA | |||||||||||||
| ARG | C:250 | C:262 | 150.0 | 0.667 | E | -68.8 | -50.4 | 134.0 | 0.596 | 0.071 |
A:P35240:0.071 |
HOH |
3.372 |
NH2 |
O |
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| ARG | D:250 | D:262 | 150.0 | 0.667 | E | -68.5 | -50.2 | NA | NA | NA | |||||||||||||
| 3wa0 | 1 | P46662 | 99.32 | 0.0 |
X-RAY |
2014-05-28 | ARG | A:249 | A:262 | 58.0 | NA | E | -70.9 | -53.1 | 29.0 | NA | NA |
G:Q9Y4B6:NA |
HOH |
3.992 |
CB |
O |
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| ARG | B:249 | B:262 | 56.0 | NA | E | -75.8 | -49.9 | NA | NA | NA | |||||||||||||
| ARG | C:249 | C:262 | 69.0 | NA | E | -71.0 | -51.2 | NA | NA | NA | |||||||||||||
| ARG | D:249 | D:262 | 54.0 | NA | E | -61.9 | -60.0 | NA | NA | NA | |||||||||||||
| ARG | E:249 | E:262 | 47.0 | NA | E | -63.0 | -58.5 | NA | NA | NA | |||||||||||||
| ARG | F:249 | F:262 | 61.0 | NA | E | -78.3 | -46.4 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p35240-f1 | 1 | P35240 | 100.0 | 0.0 | ARG | A:262 | A:262 | 106.0 | 0.471 | E | -84.4 | -46.4 | |