Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30061031 . C A CCDS13861.1:NM_000268.3:c.863tCa>tAa_NP_000259.1:p.288S>* Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 SER A:288 A:288 69.0 0.6 -78.1 -50.0 69.0 0.6 0.0 HOH
 5.255
 OG
 O
SER B:288 B:288 69.0 0.6 S -71.7 -54.1 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 SER A:288 A:288 89.0 0.774 S -73.6 -26.7 89.0 0.774 0.0 HOH
 3.072
 N
 O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 SER A:271 A:288 64.0 0.557 -127.2 110.4 64.0 0.557 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 SER A:288 A:288 91.0 0.791 -98.7 -7.2 91.0 0.791 0.0 GOL
HOH
 3.278
4.166
 O
CB
 O1
O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 SER A:292 A:288 81.0 0.704 -82.5 -27.2 81.0 0.704 0.0
SER B:292 B:288 115.0 1.0 S -79.9 -47.7 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 SER A:292 A:288 85.0 0.739 -82.3 -46.9 85.0 0.739 0.0
SER B:292 B:288 97.0 0.843 -85.7 -49.2 NA NA NA
SER C:292 C:288 94.0 0.817 -85.7 -50.1 NA NA NA
SER D:292 D:288 100.0 0.87 S -80.0 -53.0 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 SER A:289 A:288 103.0 0.896 -85.1 -37.5 103.0 0.896 0.0 HOH
 3.110
 N
 O
SER B:289 B:288 109.0 0.948 -67.6 -38.5 109.0 0.948 0.0 HOH
 2.824
 O
 O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 SER A:292 A:288 83.0 0.722 -74.1 -28.5 83.0 0.722 0.0
SER B:292 B:288 89.0 0.774 -66.6 -76.4 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 SER A:276 A:288 65.0 0.565 S -72.4 -36.2 65.0 0.565 0.0 HOH
 2.753
 OG
 O
SER B:276 B:288 64.0 0.557 S -73.6 -35.5 NA NA NA
SER C:276 C:288 80.0 0.696 S -73.3 -35.5 80.0 0.696 0.0 HOH
 3.002
 OG
 O
SER D:276 D:288 73.0 0.635 S -73.8 -36.1 NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 SER A:275 A:288 72.0 0.626 -73.9 -62.3 72.0 0.626 0.0 HOH
 5.794
 OG
 O
SER B:275 B:288 82.0 0.713 S -62.2 -59.1 NA NA NA
SER C:275 C:288 104.0 0.904 -76.3 -37.9 NA NA NA
SER D:275 D:288 99.0 0.861 S -64.6 -56.8 NA NA NA
SER E:275 E:288 58.0 0.504 -61.5 -57.6 NA NA NA
SER F:275 F:288 80.0 0.696 -71.0 -54.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 SER A:288 A:288 80.0 0.696 S -67.3 -34.8