Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 30061039 . C A CCDS13861.1:NM_000268.3:c.871Cgt>Agt_NP_000259.1:p.291R>S Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6cds 1 P35240 99.71 0.0 X-RAY
 2018-07-18 ARG A:291 A:291 133.0 0.591 H -62.4 -39.0 133.0 0.591 0.0 HOH
 3.028
 NE
 O
ARG B:291 B:291 125.0 0.556 H -62.1 -39.0 NA NA NA
7lwh 1 P35240 99.41 0.0 X-RAY
 2021-08-11 ARG A:291 A:291 109.0 0.484 H -62.9 -38.9 109.0 0.484 0.0 HOH
 2.694
 O
 O
1isn 1 P46662 99.38 0.0 X-RAY
 2002-04-03 ARG A:274 A:291 64.0 0.284 T -92.2 -46.2 64.0 0.284 0.0
4zrj 1 P35240 100.0 0.0 X-RAY
 2015-06-17 ARG A:291 A:291 108.0 0.48 H -63.1 -34.5 108.0 0.48 0.0 GOL
GOL
GOL
HOH
 4.475
3.397
9.960
2.823
 NH1
N
CD
O
 O1
O2
O1
O
4zri 1 P35240 100.0 0.0 X-RAY
 2015-06-17 ARG A:295 A:291 109.0 0.484 H -61.3 -42.6 109.0 0.484 0.0
ARG B:295 B:291 120.0 0.533 H -57.2 -54.7 NA NA NA
4zrk 1 P46662 99.38 0.0 X-RAY
 2015-06-17 ARG A:295 A:291 87.0 0.387 H -62.0 -42.8 87.0 0.387 0.0
ARG B:295 B:291 121.0 0.538 H -61.4 -46.5 NA NA NA
ARG C:295 C:291 130.0 0.578 H -59.9 -47.4 NA NA NA
ARG D:295 D:291 46.0 NA H -60.9 -41.3 NA NA NA
1h4r 1 P35240 100.0 0.0 X-RAY
 2002-01-16 ARG A:292 A:291 63.0 0.28 H -68.8 -32.3 63.0 0.28 0.0 HOH
 2.862
 O
 O
ARG B:292 B:291 70.0 0.311 H -65.8 -29.5 70.0 0.311 0.0 HOH
 2.863
 NH2
 O
4p7i 1 P46662 99.36 0.0 X-RAY
 2014-04-09 ARG A:295 A:291 107.0 0.476 H -67.5 -32.0 107.0 0.476 0.0 HOH
 5.255
 O
 O
ARG B:295 B:291 95.0 0.422 H -59.3 -32.6 NA NA NA
3u8z 1 P35240 100.0 0.0 X-RAY
 2011-11-02 ARG A:279 A:291 95.0 0.422 H -64.9 -33.3 95.0 0.422 0.0 HOH
 3.070
 NH2
 O
ARG B:279 B:291 69.0 0.307 H -62.3 -42.7 NA NA NA
ARG C:279 C:291 97.0 0.431 H -65.0 -39.4 97.0 0.431 0.0 HOH
 8.564
 C
 O
ARG D:279 D:291 100.0 0.444 H -64.1 -38.5 NA NA NA
3wa0 1 P46662 99.32 0.0 X-RAY
 2014-05-28 ARG A:278 A:291 127.0 0.564 H -60.3 -40.2 127.0 0.564 0.0 HOH
 3.448
 O
 O
ARG B:278 B:291 56.0 NA H -56.1 -41.1 NA NA NA
ARG C:278 C:291 100.0 0.444 H -76.7 -22.4 NA NA NA
ARG D:278 D:291 90.0 0.4 H -73.8 -20.6 NA NA NA
ARG E:278 E:291 100.0 0.444 H -67.1 -32.1 NA NA NA
ARG F:278 F:291 79.0 0.351 H -72.1 -22.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35240-f1 1 P35240 100.0 0.0 ARG A:291 A:291 96.0 0.427 H -65.1 -34.1