Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr22 | 30064370 | . | A | C | CCDS13861.1:NM_000268.3:c.934Aaa>Caa_NP_000259.1:p.312K>Q | Homo sapiens neurofibromin 2 (NF2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6cds | 1 | P35240 | 99.71 | 0.0 |
X-RAY |
2018-07-18 | LYS | A:312 | A:312 | 116.0 | 0.58 | H | -65.1 | -40.4 | 116.0 | 0.58 | 0.0 |
PIO HOH |
5.964 5.047 |
C O |
O51 O |
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| LYS | B:312 | B:312 | 120.0 | 0.6 | H | -80.4 | -40.4 | NA | NA | NA | |||||||||||||
| 7lwh | 1 | P35240 | 99.41 | 0.0 |
X-RAY |
2021-08-11 | LYS | A:312 | A:312 | 146.0 | 0.73 | S | -113.9 | 159.5 | 146.0 | 0.73 | 0.0 |
HOH |
2.776 |
O |
O |
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| 1isn | 1 | P46662 | 99.38 | 0.0 |
X-RAY |
2002-04-03 | LYS | A:295 | A:312 | 142.0 | 0.71 | S | -90.4 | 173.7 | 142.0 | 0.71 | 0.0 | ||||||
| 4zrj | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2015-06-17 | LYS | A:312 | A:312 | 154.0 | 0.77 | T | -91.4 | 4.5 | 154.0 | 0.77 | 0.0 |
HOH |
4.399 |
NZ |
O |
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| 4zri | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2015-06-17 | LYS | A:316 | A:312 | 128.0 | NA | -158.3 | 360.0 | 128.0 | NA | NA | |||||||
| LYS | B:316 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4zrk | 1 | P46662 | 99.38 | 0.0 |
X-RAY |
2015-06-17 | LYS | A:316 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| LYS | B:316 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| LYS | C:316 | C:312 | 140.0 | 0.7 | -138.5 | -134.2 | NA | NA | NA | ||||||||||||||
| LYS | D:316 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 1h4r | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2002-01-16 | LYS | A:313 | A:312 | 184.0 | 0.92 | T | 62.3 | 32.9 | 184.0 | 0.92 | 0.0 |
HOH |
3.920 |
CA |
O |
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| LYS | B:313 | B:312 | 156.0 | 0.78 | 165.4 | -171.1 | 156.0 | 0.78 | 0.0 |
HOH |
2.987 |
O |
O |
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| 4p7i | 1 | P46662 | 99.36 | 0.0 |
X-RAY |
2014-04-09 | LYS | A:316 | A:312 | 220.0 | 1.0 | -59.6 | 360.0 | 186.0 | 0.93 | 0.07 |
C:Q9Y4B6:0.17 |
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| LYS | B:316 | B:312 | 185.0 | 0.925 | -52.3 | 360.0 | NA | NA | NA | ||||||||||||||
| 3u8z | 1 | P35240 | 100.0 | 0.0 |
X-RAY |
2011-11-02 | LYS | A:300 | A:312 | 230.0 | 1.0 | 62.8 | 360.0 | 230.0 | 1.0 | 0.0 |
HOH |
3.343 |
O |
O |
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| LYS | B:300 | B:312 | 219.0 | 1.0 | 62.2 | 360.0 | NA | NA | NA | ||||||||||||||
| LYS | C:300 | C:312 | 231.0 | 1.0 | 62.0 | 360.0 | 231.0 | 1.0 | 0.0 |
HOH |
3.813 |
O |
O |
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| LYS | D:300 | D:312 | 228.0 | 1.0 | 60.9 | 360.0 | NA | NA | NA | ||||||||||||||
| 3wa0 | 1 | P46662 | 99.32 | 0.0 |
X-RAY |
2014-05-28 | LYS | A:299 | A:312 | 192.0 | 0.96 | -77.8 | 360.0 | 192.0 | 0.96 | 0.0 | |||||||
| LYS | B:299 | B:312 | 195.0 | 0.975 | -70.1 | 360.0 | NA | NA | NA | ||||||||||||||
| LYS | C:299 | C:312 | 141.0 | 0.705 | -68.4 | 122.0 | NA | NA | NA | ||||||||||||||
| LYS | D:299 | D:312 | 156.0 | 0.78 | H | -109.3 | -36.2 | NA | NA | NA | |||||||||||||
| LYS | E:299 | E:312 | 129.0 | NA | -93.9 | 360.0 | NA | NA | NA | ||||||||||||||
| LYS | F:299 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p35240-f1 | 1 | P35240 | 100.0 | 0.0 | LYS | A:312 | A:312 | 144.0 | 0.72 | S | -100.4 | 156.0 | |