Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 41566460 . A C CCDS14010.1:NM_001429.3:c.4337tAt>tCt_NP_001420.2:p.1446Y>S Homo sapiens E1A binding protein p300 (EP300), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6gyr 1 Q09472 94.67 0.0 X-RAY
 2018-10-17 TYR A:402 A:1446 2.0 0.009 S -72.5 -48.0 2.0 0.009 0.0 01K
 2.208
 HE2
 H19
TYR B:402 B:1446 0.0 0.0 S -81.4 -53.1 NA NA NA
TYR C:402 C:1446 1.0 0.004 S -83.6 -46.8 NA NA NA
TYR D:402 D:1446 1.0 0.004 S -68.4 -72.2 NA NA NA
4bhw 1 Q09472 88.31 0.0 X-RAY
 2013-08-14 TYR A:414 A:1446 1.0 0.004 S -76.5 -47.7 1.0 0.004 0.0 01K
HOH
 3.437
4.169
 OH
CE1
 CG
O
TYR B:414 B:1446 1.0 0.004 S -70.5 -56.5 1.0 0.004 0.0 01K
HOH
 3.526
5.688
 CD2
O
 N17
O
5lkt 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 TYR A:414 A:1446 54.0 0.235 S -69.5 -49.1 54.0 0.235 0.0 BCO
GOL
HOH
 3.418
9.452
2.937
 CD2
O
N
 N7
C1
O
5lku 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 TYR A:414 A:1446 51.0 0.222 S -68.1 -47.8 51.0 0.222 0.0 COA
HOH
 3.709
4.193
 CE2
CE1
 C2P
O
5lkx 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 TYR A:414 A:1446 54.0 0.235 S -71.6 -48.1 54.0 0.235 0.0 1VU
GOL
HOH
 3.606
9.854
2.847
 OH
O
N
 C1
C1
O
5lkz 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 TYR A:414 A:1446 54.0 0.235 S -69.2 -49.8 54.0 0.235 0.0 COO
GOL
HOH
 3.801
9.744
3.059
 CD2
O
N
 N2
C1
O
5u7g 1 Q8QZV8 80.77 0.0 X-RAY
 2017-06-21 TYR A:410 A:1483 39.0 0.17 S -65.1 -60.8 39.0 0.17 0.0 HOH
 6.768
 O
 O
TYR B:410 B:1483 38.0 0.165 S -64.8 -58.3 NA NA NA
3biy 1 Q09472 99.47 0.0 X-RAY
 2008-02-12 TYR A:160 A:1446 2.0 0.009 S -75.6 -50.6 2.0 0.009 0.0 01K
HOH
 3.616
2.894
 CE2
N
 N17
O
4pzr 1 Q09472 99.74 0.0 X-RAY
 2014-06-11 TYR A:160 A:1446 45.0 0.196 S -72.5 -47.9 45.0 0.196 0.0 PEG
PEG
COA
HOH
 3.424
3.409
3.750
2.885
 OH
CE1
CD2
N
 O2
H11
C6P
O
4pzs 1 Q09472 99.74 0.0 X-RAY
 2014-06-11 TYR A:160 A:1446 41.0 0.178 S -69.6 -53.1 41.0 0.178 0.0 ACO
HOH
 3.639
2.851
 CD2
N
 C6P
O
4pzt 1 Q09472 99.74 0.0 X-RAY
 2014-06-11 TYR A:160 A:1446 43.0 0.187 S -70.4 -56.1 43.0 0.187 0.0 SOP
DMS
HOH
 3.214
8.374
3.067
 CE2
OH
N
 OA1
O
O
6v8b 1 Q09472 91.32 0.0 X-RAY
 2020-04-01 TYR A:161 A:1446 48.0 0.209 S -74.0 -57.7 48.0 0.209 0.0 QRY
CL
CL
 3.665
4.257
9.966
 CE2
CE2
O
 C19
CL
CL
6v8n 1 Q09472 91.32 0.0 X-RAY
 2020-04-01 TYR A:161 A:1446 39.0 0.17 S -73.4 -49.4 39.0 0.17 0.0 CL
QS1
HOH
 3.704
3.765
5.231
 CE2
CE2
CE2
 CL
C14
O
6v90 1 Q09472 91.32 0.0 X-RAY
 2020-04-01 TYR A:161 A:1446 31.0 0.135 S -74.3 -53.5 31.0 0.135 0.0 QSD
CL
HOH
 3.841
3.692
2.672
 CE2
CE2
N
 CBD
CL
O
5kj2 1 Q09472 91.05 0.0 X-RAY
 2017-09-27 TYR A:160 A:1446 44.0 0.191 S -84.8 -79.1 44.0 0.191 0.0 6TF
NA
HOH
 3.757
3.561
3.439
 CD1
CE1
CE2
 C18
NA
O
7lje 1 Q09472 91.05 0.0 X-RAY
 2021-03-17 TYR A:160 A:1446 23.0 0.1 S -93.8 -41.2 23.0 0.1 0.0 Y2P
HOH
 3.127
3.683
 N
CD2
 F4
O
TYR B:160 B:1446 35.0 0.152 S -90.3 -41.5 NA NA NA
TYR C:160 C:1446 23.0 0.1 S -94.9 -43.2 NA NA NA
TYR D:160 D:1446 21.0 0.091 S -89.9 -42.4 NA NA NA
6pgu 1 Q09472 82.8 0.0 X-RAY
 2019-10-23 TYR A:162 A:1446 21.0 0.091 S -73.1 -46.7 21.0 0.091 0.0 COA
HOH
 3.562
2.797
 CE2
OH
 N4P
O
TYR B:162 B:1446 36.0 0.157 S -65.5 -50.5 NA NA NA
6v8k 1 Q09472 82.8 0.0 X-RAY
 2020-04-01 TYR A:162 A:1446 33.0 0.143 S -68.9 -54.0 33.0 0.143 0.0 COA
QS4
DMS
HOH
 3.747
3.674
8.212
2.849
 CE2
OH
OH
N
 S1P
C3
O
O
6pf1 1 Q09472 82.8 0.0 X-RAY
 2019-10-23 TYR A:177 A:1446 43.0 0.187 S -85.4 -48.5 43.0 0.187 0.0 COA
HOH
 3.688
2.904
 CE2
N
 N4P
O
TYR B:177 B:1446 44.0 0.191 S -75.7 -51.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q09472-f1 1 Q09472 100.0 0.0 TYR A:1446 A:1446 36.0 0.157 S -81.1 -39.2