Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 41572254 . T A CCDS14010.1:NM_001429.3:c.4783Ttc>Atc_NP_001420.2:p.1595F>I Homo sapiens E1A binding protein p300 (EP300), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6gyr 1 Q09472 94.67 0.0 X-RAY
 2018-10-17 PHE A:519 A:1595 13.0 0.062 E -120.4 116.7 13.0 0.062 0.0 01K
 5.822
 HE1
 HDA
PHE B:519 B:1595 9.0 0.043 E -106.9 142.8 NA NA NA
PHE C:519 C:1595 9.0 0.043 E -123.2 127.3 NA NA NA
PHE D:519 D:1595 9.0 0.043 E -106.0 129.0 NA NA NA
4bhw 1 Q09472 88.31 0.0 X-RAY
 2013-08-14 PHE A:507 A:1595 10.0 0.048 E -122.0 98.6 10.0 0.048 0.0 01K
HOH
 7.607
7.433
 CE1
CE1
 CD
O
PHE B:507 B:1595 12.0 0.057 E -107.8 104.6 12.0 0.057 0.0 01K
 7.599
 CE1
 CD
5lkt 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 PHE A:507 A:1595 12.0 0.057 E -120.4 111.7 12.0 0.057 0.0 BCO
DMS
HOH
 7.386
3.672
3.044
 CE1
CD1
O
 C25
C1
O
5lku 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 PHE A:507 A:1595 12.0 0.057 E -119.4 111.2 12.0 0.057 0.0 COA
HOH
 9.757
3.415
 CE1
CD1
 S1P
O
5lkx 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 PHE A:507 A:1595 11.0 0.052 E -120.3 110.1 11.0 0.052 0.0 1VU
DMS
HOH
 8.072
3.565
5.035
 CE1
CD1
CZ
 C
C2
O
5lkz 1 Q09472 88.31 0.0 X-RAY
 2016-11-02 PHE A:507 A:1595 12.0 0.057 E -120.2 112.1 12.0 0.057 0.0 COO
GOL
HOH
 7.385
3.702
4.813
 CE1
CB
CZ
 C10
C1
O
5u7g 1 Q8QZV8 80.77 0.0 X-RAY
 2017-06-21 PHE A:503 A:1633 11.0 0.052 E -118.3 118.1 11.0 0.052 0.0 HOH
 3.586
 CD1
 O
PHE B:503 B:1633 13.0 0.062 E -116.0 118.2 NA NA NA
3biy 1 Q09472 99.47 0.0 X-RAY
 2008-02-12 PHE A:309 A:1595 10.0 0.048 E -119.9 115.1 10.0 0.048 0.0 01K
HOH
 7.542
3.148
 CE1
O
 CD
O
4pzr 1 Q09472 99.74 0.0 X-RAY
 2014-06-11 PHE A:309 A:1595 10.0 0.048 E -120.3 121.7 10.0 0.048 0.0 PEG
DMS
COA
HOH
 7.096
3.574
9.287
2.813
 CE1
CD1
N
O
 H12
S
S1P
O
4pzs 1 Q09472 99.74 0.0 X-RAY
 2014-06-11 PHE A:309 A:1595 12.0 0.057 E -123.0 116.4 12.0 0.057 0.0 ACO
DMS
HOH
 8.778
3.656
3.292
 CD1
CD1
O
 O
O
O
4pzt 1 Q09472 99.74 0.0 X-RAY
 2014-06-11 PHE A:309 A:1595 11.0 0.052 E -119.7 112.8 11.0 0.052 0.0 SOP
DMS
DMS
DMS
HOH
 8.683
2.731
3.817
3.650
6.560
 CE1
CD1
CE2
O
CE2
 CA3
H12
H23
O
O
6v8b 1 Q09472 91.32 0.0 X-RAY
 2020-04-01 PHE A:278 A:1595 9.0 0.043 E -119.1 108.0 9.0 0.043 0.0
6v8n 1 Q09472 91.32 0.0 X-RAY
 2020-04-01 PHE A:278 A:1595 10.0 0.048 E -115.5 116.2 10.0 0.048 0.0 HOH
 3.111
 O
 O
6v90 1 Q09472 91.32 0.0 X-RAY
 2020-04-01 PHE A:278 A:1595 11.0 0.052 E -118.3 113.0 11.0 0.052 0.0 HOH
 3.124
 O
 O
5kj2 1 Q09472 91.05 0.0 X-RAY
 2017-09-27 PHE A:277 A:1595 9.0 0.043 E -115.3 112.1 9.0 0.043 0.0 HOH
 3.254
 O
 O
7lje 1 Q09472 91.05 0.0 X-RAY
 2021-03-17 PHE A:277 A:1595 10.0 0.048 E -111.5 120.7 10.0 0.048 0.0 HOH
 4.101
 CE2
 O
PHE B:277 B:1595 11.0 0.052 E -115.9 122.6 NA NA NA
PHE C:277 C:1595 10.0 0.048 E -109.7 120.4 NA NA NA
PHE D:277 D:1595 10.0 0.048 E -112.3 121.9 NA NA NA
6pgu 1 Q09472 82.8 0.0 X-RAY
 2019-10-23 PHE A:255 A:1595 16.0 0.076 E -120.2 103.8 16.0 0.076 0.0 COA
OK7
HOH
 9.824
3.777
3.200
 CE1
CD1
O
 S1P
CAC
O
PHE B:255 B:1595 12.0 0.057 E -119.5 110.6 NA NA NA
6v8k 1 Q09472 82.8 0.0 X-RAY
 2020-04-01 PHE A:255 A:1595 13.0 0.062 E -116.0 118.3 13.0 0.062 0.0 QS4
DMS
HOH
 7.178
4.036
3.063
 CE1
CE2
O
 C5
C1
O
6pf1 1 Q09472 82.8 0.0 X-RAY
 2019-10-23 PHE A:270 A:1595 11.0 0.052 E -124.2 117.7 11.0 0.052 0.0 COA
OJ7
HOH
 9.911
3.564
7.568
 CE1
CD1
CD1
 S1P
C6
O
PHE B:270 B:1595 15.0 0.071 E -122.9 107.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q09472-f1 1 Q09472 100.0 0.0 PHE A:1595 A:1595 12.0 0.057 E -124.6 108.8