Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr22 41648913 . C A CCDS14012.1:NM_001278651.1:c.1343cGc>cTc_NP_001265580.1:p.448R>L Homo sapiens Ran GTPase activating protein 1 (RANGAP1), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5d2m 3 P46060 100.0 6e-119 X-RAY
 2015-11-04 ARG C:32 C:448 220.0 0.978 H -65.7 -13.7 220.0 0.978 0.0 HOH
 2.009
 HE
 O
ARG F:32 F:448 218.0 0.969 H -66.8 -18.4 NA NA NA
1z5s 3 P46060 100.0 7e-119 X-RAY
 2005-06-07 ARG C:33 C:448 222.0 0.987 G -68.5 32.6 222.0 0.987 0.0
2grn 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 ARG B:31 B:448 106.0 0.471 T -68.6 -15.1 106.0 0.471 0.0 HOH
 3.338
 NH2
 O
2gro 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 ARG B:31 B:448 131.0 0.582 T -71.3 -10.7 131.0 0.582 0.0 HOH
 3.120
 O
 O
2grp 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 ARG B:31 B:448 106.0 0.471 T -72.0 -5.8 106.0 0.471 0.0 HOH
 3.911
 CD
 O
2grq 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 ARG B:31 B:448 127.0 0.564 H -65.7 -18.3 127.0 0.564 0.0 HOH
 2.905
 NH2
 O
2grr 2 P46060 99.41 4e-118 X-RAY
 2006-05-30 ARG B:31 B:448 133.0 0.591 H -66.6 -18.9 133.0 0.591 0.0 HOH
 2.803
 NE
 O
3uin 3 P46060 100.0 5e-118 X-RAY
 2011-12-28 ARG C:32 C:448 216.0 0.96 H -74.8 -9.4 216.0 0.96 0.0
3uio 3 P46060 100.0 5e-118 X-RAY
 2011-12-28 ARG C:32 C:448 213.0 0.947 T -63.5 -6.8 213.0 0.947 0.0
3uip 3 P46060 100.0 5e-118 X-RAY
 2011-12-28 ARG C:32 C:448 222.0 0.987 H -70.8 -11.8 222.0 0.987 0.0 HOH
 2.841
 NE
 O
2io2 3 P46060 99.41 1e-117 X-RAY
 2006-11-21 ARG C:33 C:448 155.0 0.689 T -92.5 52.9 155.0 0.689 0.0
2io3 3 P46060 99.41 1e-117 X-RAY
 2006-11-14 ARG C:33 C:448 177.0 0.787 T -81.3 49.2 177.0 0.787 0.0
2iy0 3 P46060 100.0 2e-107 X-RAY
 2006-08-07 ARG C:17 C:448 180.0 0.8 H -75.5 -36.1 180.0 0.8 0.0
1kps 2 P46061 81.76 3e-98 X-RAY
 2002-02-13 ARG B:32 B:450 162.0 0.72 H -65.6 -29.9 162.0 0.72 0.0 HOH
 3.063
 CA
 O
ARG D:32 D:450 174.0 0.773 T -65.2 30.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p46060-f1 1 P46060 100.0 0.0 ARG A:448 A:448 114.0 0.507 H -70.0 -18.5