Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 105572480 . T A CCDS2948.1:NM_170662.3:c.197cAg>cTg_NP_733762.2:p.66Q>L Homo sapiens Cbl proto-oncogene B, E3 ubiquitin protein ligase (CBLB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zni 1 Q13191 99.49 0.0 X-RAY
 2013-07-10 GLN A:33 A:66 166.0 0.922 52.4 48.5 166.0 0.922 0.0 HOH
 3.162
 C
 O
GLN E:33 E:66 168.0 0.933 49.9 51.4 NA NA NA
GLN I:33 I:66 167.0 0.928 46.9 53.6 NA NA NA
GLN M:33 M:66 169.0 0.939 50.9 50.3 NA NA NA
3vgo 1 Q13191 100.0 0.0 X-RAY
 2011-12-14 GLN A:34 A:66 81.0 NA 35.5 50.2 81.0 NA NA
GLN B:34 B:66 162.0 0.9 65.3 69.1 NA NA NA
GLN C:34 C:66 166.0 0.922 54.1 41.7 NA NA NA
4a4c 1 P22681 85.6 0.0 X-RAY
 2012-01-25 ALA A:32 A:76 78.0 0.678 49.2 53.9 78.0 0.678 0.0 HOH
 8.303
 O
 O
2y1m 1 P22681 85.6 0.0 X-RAY
 2012-01-18 ALA A:30 A:76 75.0 0.652 44.3 50.1 75.0 0.652 0.0 HOH
 8.147
 C
 O
ALA B:30 B:76 73.0 0.635 54.5 72.1 NA NA NA
ALA C:30 C:76 76.0 0.661 46.9 60.5 NA NA NA
ALA D:30 D:76 66.0 0.574 67.7 54.4 NA NA NA
ALA E:30 E:76 62.0 0.539 39.0 70.0 NA NA NA
ALA F:30 F:76 72.0 0.626 59.5 48.3 NA NA NA
2y1n 1 P22681 85.6 0.0 X-RAY
 2012-01-18 ALA A:30 A:76 65.0 0.565 60.4 55.2 NA NA NA
ALA C:30 C:76 76.0 0.661 77.1 44.0 76.0 0.661 0.0 HOH
 4.024
 N
 O
4a4b 1 P22681 85.35 0.0 X-RAY
 2012-01-25 ALA A:32 A:76 81.0 0.704 47.0 63.4 81.0 0.704 0.0 HOH
 5.036
 O
 O
5o76 1 P22681 85.35 0.0 X-RAY
 2017-11-01 ALA A:32 A:76 75.0 0.652 45.8 36.6 75.0 0.652 0.0
ALA C:32 C:76 71.0 0.617 56.2 80.2 NA NA NA
5j3x 1 P22681 85.35 0.0 X-RAY
 2016-09-21 ALA A:32 A:76 72.0 0.626 54.4 68.2 72.0 0.626 0.0 HOH
 8.084
 O
 O
ALA B:32 B:76 78.0 0.678 55.4 70.5 NA NA NA
ALA C:32 C:76 73.0 0.635 50.2 57.2 NA NA NA
ALA D:32 D:76 74.0 0.643 55.7 67.0 NA NA NA
ALA E:32 E:76 55.0 0.478 53.3 71.1 NA NA NA
ALA F:32 F:76 81.0 0.704 51.4 59.1 NA NA NA
1fbv 1 P22681 85.57 0.0 X-RAY
 2000-08-30 ALA A:30 A:76 71.0 0.617 34.9 59.5 71.0 0.617 0.0
5hkx 1 P22681 85.35 0.0 X-RAY
 2017-01-18 ALA A:33 A:76 69.0 0.6 46.7 53.1 69.0 0.6 0.0 HOH
 3.627
 N
 O
3pfv 1 Q13191 99.68 0.0 X-RAY
 2010-12-08 GLN A:30 A:66 172.0 0.956 50.0 42.8 172.0 0.956 0.0 HOH
 6.072
 O
 O
GLN B:30 B:66 76.0 NA 67.5 63.6 NA NA NA
5axi 1 Q3TTA7 100.0 0.0 X-RAY
 2016-03-02 GLN A:30 A:66 170.0 0.944 48.4 52.2 170.0 0.944 0.0
GLN B:30 B:66 169.0 0.939 41.6 49.7 NA NA NA
GLN C:30 C:66 168.0 0.933 44.7 51.0 NA NA NA
6xar 1 P22681 83.28 0.0 X-RAY
 2021-03-03 ALA A:54 A:76 86.0 0.748 55.4 85.5 86.0 0.748 0.0 HOH
 3.329
 CB
 O
ALA B:54 B:76 90.0 0.783 55.2 48.0 NA NA NA
6o02 1 P22681 83.06 0.0 X-RAY
 2020-08-19 ALA A:32 A:76 73.0 0.635 55.8 48.7 73.0 0.635 0.0
6o03 1 P22681 82.74 0.0 X-RAY
 2020-08-19 ALA A:32 B:76 75.0 0.652 57.4 45.5 75.0 0.652 0.0
ALA C:32 A:76 83.0 0.722 61.1 43.8 NA NA NA
5hkw 1 P22681 82.95 0.0 X-RAY
 2017-01-18 ALA A:33 A:76 65.0 0.565 49.4 35.6 65.0 0.565 0.0 HOH
 4.842
 N
 O
ALA B:33 B:76 65.0 0.565 53.8 38.9 NA NA NA
ALA C:33 C:76 80.0 0.696 34.6 55.2 NA NA NA
5hky 1 P22681 82.95 0.0 X-RAY
 2017-01-18 ALA A:33 A:76 78.0 0.678 54.8 40.0 78.0 0.678 0.0 HOH
 2.556
 O
 O
5hkz 1 P22681 82.95 0.0 X-RAY
 2017-01-18 ALA A:33 A:76 76.0 0.661 62.0 45.0 76.0 0.661 0.0 HOH
 3.833
 N
 O
5hl0 1 P22681 82.95 0.0 X-RAY
 2017-01-18 ALA A:33 A:76 84.0 0.73 50.1 43.3 84.0 0.73 0.0 HOH
 4.309
 N
 O
4gpl 2 P22681 82.95 0.0 X-RAY
 2013-09-18 ALA B:34 B:76 77.0 0.67 53.2 57.8 77.0 0.67 0.0 HOH
 8.656
 O
 O
1yvh 1 P22681 82.95 0.0 X-RAY
 2005-03-08 ALA A:54 A:76 81.0 0.704 60.1 40.8 81.0 0.704 0.0 HOH
 2.760
 O
 O
3bum 2 P22681 82.95 0.0 X-RAY
 2008-02-26 ALA B:54 B:76 82.0 0.713 58.1 32.7 NA NA NA
3bun 2 P22681 82.95 0.0 X-RAY
 2008-02-26 ALA B:54 B:76 84.0 0.73 51.7 39.2 NA NA NA
3buo 2 P22681 82.95 0.0 X-RAY
 2008-02-26 ALA B:54 B:76 77.0 0.67 44.7 48.8 77.0 0.67 0.0 HOH
 6.987
 N
 O
ALA D:54 D:76 76.0 0.661 44.4 49.9 NA NA NA
3buw 2 P22681 82.95 0.0 X-RAY
 2008-02-26 ALA B:54 B:76 79.0 0.687 54.4 35.4 NA NA NA
ALA D:54 D:76 77.0 0.67 52.7 38.6 NA NA NA
3bux 2 P22681 82.95 0.0 X-RAY
 2008-02-26 ALA B:54 B:76 77.0 0.67 51.6 37.9 NA NA NA
ALA D:54 D:76 77.0 0.67 50.9 34.8 NA NA NA
3ob1 2 P22681 82.95 0.0 X-RAY
 2010-08-18 ALA B:54 B:76 81.0 0.704 41.1 51.4 81.0 0.704 0.0 HOH
 3.390
 N
 O
3ob2 2 P22681 82.95 0.0 X-RAY
 2010-08-18 ALA B:54 B:76 77.0 0.67 53.0 38.4 77.0 0.67 0.0 HOH
 3.011
 N
 O
3plf 2 P22681 82.95 0.0 X-RAY
 2010-12-01 ALA B:54 B:76 71.0 0.617 58.4 44.1 71.0 0.617 0.0 HOH
 3.723
 O
 O
ALA D:54 D:76 73.0 0.635 56.1 45.4 NA NA NA
2cbl 1 P22681 82.95 0.0 X-RAY
 1999-05-18 ALA A:30 A:76 77.0 0.67 57.2 47.6 19.0 0.165 0.505 A:P22681:0.504
 HOH
 2.835
 N
 O
1b47 1 P22681 82.89 0.0 X-RAY
 1999-04-27 ALA A:30 A:76 79.0 0.687 55.2 44.4 79.0 0.687 0.0 HOH
 4.874
 C
 O
ALA B:30 B:76 82.0 0.713 42.5 50.7 82.0 0.713 0.0 HOH
 4.321
 CB
 O
ALA C:30 C:76 67.0 0.583 69.2 48.6 67.0 0.583 0.0 HOH
 8.631
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q13191-f1 1 Q13191 100.0 0.0 GLN A:66 A:66 152.0 0.844 50.4 49.9