Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 114014398 . T A CCDS2980.1:NM_173799.3:c.68aTg>aAg_NP_776160.2:p.23M>K Homo sapiens T-cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3q0h 1 Q495A1 100.0 1e-82 X-RAY
 2011-02-16 MET A:3 A:23 167.0 0.903 S -85.0 -30.9 167.0 0.903 0.0 HOH
 2.462
 O
 O
MET B:3 NA:NA DO NA DO DO DO NA NA NA
3rq3 1 Q495A1 100.0 2e-82 X-RAY
 2011-06-01 MET A:2 A:23 218.0 1.0 360.0 -55.8 218.0 1.0 0.0 HOH
 6.500
 N
 O
MET B:2 B:23 107.0 0.578 -87.4 127.1 102.0 0.551 0.027 A:Q495A1:0.027
 HOH
 3.357
 CE
 O
3udw 1 Q495A1 98.18 1e-75 X-RAY
 2012-03-14 MET A:5 A:23 173.0 0.935 360.0 166.0 108.0 0.584 0.351 C:P15151:0.351
MET B:5 NA:NA DO NA DO DO DO NA NA NA
3ucr 1 Q495A1 97.27 1e-74 X-RAY
 2012-03-14 MET A:5 A:16 143.0 0.773 360.0 98.4 143.0 0.773 0.0 HOH
 6.400
 CE
 O
MET B:5 B:16 240.0 1.0 360.0 -33.3 NA NA NA
MET C:5 C:16 104.0 0.562 -72.9 135.7 104.0 0.562 0.0 HOH
 5.245
 N
 O
MET D:5 D:16 120.0 NA 360.0 -103.6 NA NA NA
5v52 1 Q495A1 99.07 1e-74 X-RAY
 2017-05-24 MET A:2 NA:NA DO NA DO DO DO NA NA NA
MET B:2 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q495a1-f1 1 Q495A1 100.0 0.0 MET A:23 A:23 161.0 0.87 -65.1 107.2