Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 114014427 . A C CCDS2980.1:NM_173799.3:c.97Att>Ctt_NP_776160.2:p.33I>L Homo sapiens T-cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3q0h 1 Q495A1 100.0 1e-82 X-RAY
 2011-02-16 ILE A:13 A:33 28.0 0.16 E -108.3 139.8 28.0 0.16 0.0 HOH
 2.927
 O
 O
ILE B:13 B:33 44.0 0.251 E -128.5 156.6 NA NA NA
3rq3 1 Q495A1 100.0 2e-82 X-RAY
 2011-06-01 ILE A:12 A:33 29.0 0.166 E -127.7 148.6 29.0 0.166 0.0
ILE B:12 B:33 29.0 0.166 E -128.4 163.0 29.0 0.166 0.0
3udw 1 Q495A1 98.18 1e-75 X-RAY
 2012-03-14 ILE A:15 A:33 29.0 0.166 -85.3 158.7 6.0 0.034 0.132 B:Q495A1:0.131
ILE B:15 B:33 37.0 0.211 E -127.1 160.5 2.0 0.011 0.2 A:Q495A1:0.2
3ucr 1 Q495A1 97.27 1e-74 X-RAY
 2012-03-14 ILE A:15 A:26 42.0 0.24 E -135.3 145.8 6.0 0.034 0.206 C:Q495A1:0.206
 HOH
 8.237
 O
 O
ILE B:15 B:26 29.0 0.166 E -123.2 146.7 NA NA NA
ILE C:15 C:26 27.0 0.154 E -98.7 135.9 3.0 0.017 0.137 A:Q495A1:0.137
ILE D:15 D:26 31.0 0.177 E -103.1 143.4 NA NA NA
5v52 1 Q495A1 99.07 1e-74 X-RAY
 2017-05-24 ILE A:12 A:33 27.0 0.154 E -84.4 152.3 27.0 0.154 0.0
ILE B:12 B:33 25.0 0.143 E -84.4 153.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q495a1-f1 1 Q495A1 100.0 0.0 ILE A:33 A:33 27.0 0.154 E -130.8 154.5