Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 114014634 . G A CCDS2980.1:NM_173799.3:c.304Gat>Aat_NP_776160.2:p.102D>N Homo sapiens T-cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3q0h 1 Q495A1 100.0 1e-82 X-RAY
 2011-02-16 ASP A:82 A:102 24.0 0.16 G -72.8 -9.5 24.0 0.16 0.0 HOH
 6.949
 O
 O
ASP B:82 B:102 12.0 0.08 G -77.4 -10.7 NA NA NA
3rq3 1 Q495A1 100.0 2e-82 X-RAY
 2011-06-01 ASP A:81 A:102 13.0 0.087 G -47.0 -19.2 13.0 0.087 0.0 HOH
 4.046
 O
 O
ASP B:81 B:102 9.0 0.06 G -72.1 -9.9 9.0 0.06 0.0
3udw 1 Q495A1 98.18 1e-75 X-RAY
 2012-03-14 ASP A:84 A:102 13.0 0.087 G -62.0 -14.0 13.0 0.087 0.0
ASP B:84 B:102 14.0 0.093 G -73.0 4.9 14.0 0.093 0.0
3ucr 1 Q495A1 97.27 1e-74 X-RAY
 2012-03-14 ASP A:84 A:95 4.0 0.027 G -86.1 -5.0 4.0 0.027 0.0 HOH
 7.362
 C
 O
ASP B:84 B:95 2.0 0.013 G -90.3 -15.4 NA NA NA
ASP C:84 C:95 5.0 0.033 G -82.5 -11.9 5.0 0.033 0.0 HOH
 9.417
 OD1
 O
ASP D:84 D:95 4.0 0.027 G -73.3 -4.7 NA NA NA
5v52 1 Q495A1 99.07 1e-74 X-RAY
 2017-05-24 ASP A:81 A:102 29.0 0.193 G -70.1 -8.2 29.0 0.193 0.0
ASP B:81 B:102 12.0 0.08 G -70.1 -8.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q495a1-f1 1 Q495A1 100.0 0.0 ASP A:102 A:102 10.0 0.067 G -81.0 -1.7