Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 114014695 . T A CCDS2980.1:NM_173799.3:c.365aTc>aAc_NP_776160.2:p.122I>N Homo sapiens T-cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3q0h 1 Q495A1 100.0 1e-82 X-RAY
 2011-02-16 ILE A:102 A:122 1.0 0.006 E -123.3 128.5 1.0 0.006 0.0 HOH
 3.669
 CG2
 O
ILE B:102 B:122 1.0 0.006 E -121.5 142.4 NA NA NA
3rq3 1 Q495A1 100.0 2e-82 X-RAY
 2011-06-01 ILE A:101 A:122 1.0 0.006 E -140.3 124.4 1.0 0.006 0.0 HOH
 5.740
 N
 O
ILE B:101 B:122 1.0 0.006 E -132.9 135.2 1.0 0.006 0.0 HOH
 5.760
 N
 O
3udw 1 Q495A1 98.18 1e-75 X-RAY
 2012-03-14 ILE A:104 A:122 1.0 0.006 E -129.5 128.0 1.0 0.006 0.0
ILE B:104 B:122 0.0 0.0 E -125.3 133.2 0.0 0.0 0.0
3ucr 1 Q495A1 97.27 1e-74 X-RAY
 2012-03-14 ILE A:104 A:115 0.0 0.0 E -135.1 137.7 0.0 0.0 0.0 HOH
 7.398
 CD1
 O
ILE B:104 B:115 1.0 0.006 E -129.3 124.5 NA NA NA
ILE C:104 C:115 1.0 0.006 E -126.0 118.6 1.0 0.006 0.0
ILE D:104 D:115 1.0 0.006 E -114.9 129.1 NA NA NA
5v52 1 Q495A1 99.07 1e-74 X-RAY
 2017-05-24 ILE A:101 A:122 0.0 0.0 E -128.2 127.9 0.0 0.0 0.0
ILE B:101 B:122 0.0 0.0 E -128.0 128.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q495a1-f1 1 Q495A1 100.0 0.0 ILE A:122 A:122 0.0 0.0 E -130.2 137.3