Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 114014703 . G A CCDS2980.1:NM_173799.3:c.373Gag>Aag_NP_776160.2:p.125E>K Homo sapiens T-cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.
pdb_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3q0h 1 Q495A1 100.0 1e-82 X-RAY
 2011-02-16 GLU A:105 A:125 84.0 0.442 E -112.3 125.1 84.0 0.442 0.0 HOH
 4.233
 CB
 O
GLU B:105 B:125 106.0 0.558 E -108.5 119.9 NA NA NA
3rq3 1 Q495A1 100.0 2e-82 X-RAY
 2011-06-01 GLU A:104 A:125 94.0 0.495 E -116.9 120.1 94.0 0.495 0.0 HOH
 9.087
 N
 O
GLU B:104 B:125 90.0 0.474 E -129.9 124.2 90.0 0.474 0.0
3udw 1 Q495A1 98.18 1e-75 X-RAY
 2012-03-14 GLU A:107 A:125 96.0 0.505 -132.8 126.9 96.0 0.505 0.0
GLU B:107 B:125 111.0 0.584 E -127.9 93.3 108.0 0.568 0.016 A:Q495A1:0.016
3ucr 1 Q495A1 97.27 1e-74 X-RAY
 2012-03-14 GLU A:107 A:118 108.0 0.568 E -110.6 121.3 108.0 0.568 0.0 HOH
 4.394
 C
 O
GLU B:107 B:118 92.0 0.484 E -113.4 133.1 NA NA NA
GLU C:107 C:118 95.0 0.5 E -103.6 121.2 95.0 0.5 0.0
GLU D:107 D:118 98.0 0.516 E -114.9 133.5 NA NA NA
5v52 1 Q495A1 99.07 1e-74 X-RAY
 2017-05-24 GLU A:104 A:125 118.0 0.621 E -126.1 119.0 118.0 0.621 0.0
GLU B:104 B:125 38.0 NA E -123.7 96.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q495a1-f1 1 Q495A1 100.0 0.0 GLU A:125 A:125 99.0 0.521 E -108.9 116.6