Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 114014706 . G A CCDS2980.1:NM_173799.3:c.376Gtc>Atc_NP_776160.2:p.126V>I Homo sapiens T-cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3q0h 1 Q495A1 100.0 1e-82 X-RAY
 2011-02-16 VAL A:106 A:126 6.0 0.039 E -113.0 127.0 6.0 0.039 0.0 HOH
 6.858
 CG1
 O
VAL B:106 B:126 6.0 0.039 E -89.4 118.5 NA NA NA
3rq3 1 Q495A1 100.0 2e-82 X-RAY
 2011-06-01 VAL A:105 A:126 6.0 0.039 E -106.3 129.4 6.0 0.039 0.0 HOH
 8.157
 CG2
 O
VAL B:105 B:126 8.0 0.052 E -98.3 122.0 8.0 0.052 0.0
3udw 1 Q495A1 98.18 1e-75 X-RAY
 2012-03-14 VAL A:108 A:126 3.0 0.019 B -115.8 127.3 3.0 0.019 0.0
VAL B:108 B:126 32.0 0.206 -97.2 360.0 32.0 0.206 0.0
3ucr 1 Q495A1 97.27 1e-74 X-RAY
 2012-03-14 VAL A:108 A:119 8.0 0.052 E -100.3 104.0 8.0 0.052 0.0 HOH
 3.202
 O
 O
VAL B:108 B:119 10.0 0.065 E -101.7 119.7 NA NA NA
VAL C:108 C:119 6.0 0.039 E -109.0 109.1 6.0 0.039 0.0
VAL D:108 D:119 7.0 0.045 E -120.0 119.9 NA NA NA
5v52 1 Q495A1 99.07 1e-74 X-RAY
 2017-05-24 VAL A:105 A:126 43.0 0.277 -111.7 360.0 43.0 0.277 0.0
VAL B:105 B:126 4.0 0.026 E -97.0 118.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q495a1-f1 1 Q495A1 100.0 0.0 VAL A:126 A:126 7.0 0.045 E -96.7 111.6