Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 133472533 | . | A | C | CCDS3080.1:NM_001063.3:c.311tAt>tCt_NP_001054.1:p.104Y>S | Homo sapiens transferrin (TF), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3v83 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2012-02-15 | TYR | A:104 | A:85 | 4.0 | 0.017 | E | -121.2 | -179.6 | 4.0 | 0.017 | 0.0 |
BCT FE SO4 HOH |
8.135 6.316 7.101 3.213 |
OH OH C CB |
O1 FE O4 O |
||
TYR | B:104 | B:85 | 4.0 | 0.017 | E | -123.1 | 178.5 | NA | NA | NA | |||||||||||||
TYR | C:104 | C:85 | 4.0 | 0.017 | E | -117.0 | -177.0 | NA | NA | NA | |||||||||||||
TYR | D:104 | D:85 | 4.0 | 0.017 | E | -124.4 | -177.8 | NA | NA | NA | |||||||||||||
TYR | E:104 | E:85 | 4.0 | 0.017 | E | -126.7 | -174.1 | NA | NA | NA | |||||||||||||
TYR | F:104 | F:85 | 4.0 | 0.017 | B | -119.6 | -177.0 | NA | NA | NA | |||||||||||||
3v8x | 2 | P02787 | 100.0 | 0.0 |
X-RAY |
2012-02-29 | TYR | B:104 | B:85 | 26.0 | 0.113 | -118.3 | 162.4 | 26.0 | 0.113 | 0.0 |
HOH |
3.398 |
CD1 |
O |
|||
6d03 | 2 | P02787 | 100.0 | 0.0 |
EM |
2018-06-20 | TYR | C:104 | C:85 | 20.0 | 0.087 | -119.8 | -18.2 | 20.0 | 0.087 | 0.0 |
FE CO3 |
5.779 7.596 |
OH OH |
FE O1 |
|||
TYR | D:104 | D:85 | 18.0 | 0.078 | -118.7 | -21.1 | 18.0 | 0.078 | 0.0 |
FE CO3 |
6.075 7.749 |
OH OH |
FE O3 |
||||||||||
6d04 | 2 | P02787 | 100.0 | 0.0 |
EM |
2018-06-20 | TYR | C:104 | C:85 | 18.0 | 0.078 | -119.0 | -15.2 | 18.0 | 0.078 | 0.0 |
FE CO3 |
5.863 7.745 |
OH OH |
FE O3 |
|||
TYR | D:104 | D:85 | 19.0 | 0.083 | -118.9 | -15.2 | 19.0 | 0.083 | 0.0 |
FE CO3 |
5.863 7.724 |
OH OH |
FE O3 |
||||||||||
6d05 | 2 | P02787 | 100.0 | 0.0 |
EM |
2018-06-20 | TYR | C:104 | C:85 | 16.0 | 0.07 | -112.4 | -14.5 | 16.0 | 0.07 | 0.0 |
FE CO3 |
5.848 7.117 |
OH OH |
FE O3 |
|||
TYR | D:104 | D:85 | 16.0 | 0.07 | -112.4 | -14.4 | 16.0 | 0.07 | 0.0 |
FE CO3 |
5.859 7.133 |
OH OH |
FE O3 |
||||||||||
5dyh | 1 | P02787 | 99.86 | 0.0 |
X-RAY |
2016-04-27 | TYR | A:104 | A:85 | 33.0 | 0.143 | S | -121.9 | 9.6 | 33.0 | 0.143 | 0.0 |
CIT |
8.356 |
OH |
O3 |
||
TYR | B:104 | B:85 | 36.0 | 0.157 | -121.0 | 9.8 | NA | NA | NA | ||||||||||||||
6uj6 | 1 | Q06AH7 | 99.71 | 0.0 |
X-RAY |
2020-09-30 | TYR | A:104 | A:104 | 25.0 | 0.109 | -129.1 | 152.0 | 25.0 | 0.109 | 0.0 |
HOH |
4.116 |
CE1 |
O |
|||
3qyt | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2012-03-14 | TYR | A:85 | A:85 | 45.0 | 0.196 | -133.6 | -5.1 | 45.0 | 0.196 | 0.0 |
FE SO4 |
9.272 8.406 |
OH OH |
FE O2 |
|||
4x1b | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2015-04-08 | TYR | A:85 | A:85 | 28.0 | 0.122 | B | -134.4 | 175.8 | 28.0 | 0.122 | 0.0 |
HOH |
3.454 |
CD2 |
O |
||
4x1d | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2015-04-08 | TYR | A:85 | A:85 | 27.0 | 0.117 | E | -133.4 | 178.0 | 27.0 | 0.117 | 0.0 |
HOH |
3.894 |
CE1 |
O |
||
TYR | B:85 | B:85 | 35.0 | 0.152 | -130.8 | -21.1 | NA | NA | NA | ||||||||||||||
5h52 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2017-11-08 | TYR | A:85 | A:85 | 29.0 | 0.126 | B | -129.1 | 164.3 | 29.0 | 0.126 | 0.0 |
CIT HOH |
7.728 4.508 |
OH CE2 |
O1 O |
||
5wtd | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | TYR | A:85 | A:85 | 28.0 | 0.122 | B | -136.0 | 170.5 | 28.0 | 0.122 | 0.0 |
HOH |
3.662 |
CD1 |
O |
||
6jas | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2020-01-29 | TYR | A:85 | A:85 | 31.0 | 0.135 | E | -134.6 | 178.3 | 31.0 | 0.135 | 0.0 |
CIT HOH |
7.885 4.365 |
OH CE2 |
O3 O |
||
4h0w | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2012-12-26 | TYR | A:85 | A:85 | 36.0 | 0.157 | -132.3 | -10.5 | 36.0 | 0.157 | 0.0 |
NTA HOH |
7.927 4.344 |
OH CE1 |
C6 O |
|||
5x5p | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2018-02-21 | TYR | A:85 | A:85 | 26.0 | 0.113 | B | -130.4 | 165.6 | 26.0 | 0.113 | 0.0 |
HOH |
4.109 |
CE1 |
O |
||
5y6k | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2018-01-24 | TYR | A:85 | A:85 | 28.0 | 0.122 | B | -134.2 | -179.5 | 28.0 | 0.122 | 0.0 |
8R6 HOH |
6.214 9.400 |
OH OH |
C21 O |
||
6ctc | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2018-10-24 | TYR | A:85 | A:85 | 38.0 | 0.165 | -138.7 | 6.0 | 38.0 | 0.165 | 0.0 |
POP HOH |
7.879 4.151 |
OH CE1 |
O1 O |
|||
3ve1 | 2 | P02787 | 99.71 | 0.0 |
X-RAY |
2012-02-22 | TYR | B:85 | B:85 | 24.0 | 0.104 | E | -129.0 | 150.3 | 24.0 | 0.104 | 0.0 |
GOL HOH |
6.022 6.045 |
OH CE2 |
O3 O |
||
TYR | D:85 | D:85 | 26.0 | 0.113 | E | -126.3 | 148.8 | NA | NA | NA | |||||||||||||
6soy | 3 | P02787 | 100.0 | 0.0 |
X-RAY |
2019-11-06 | TYR | C:83 | C:85 | 27.0 | 0.117 | -128.1 | 150.8 | 27.0 | 0.117 | 0.0 |
HOH |
8.115 |
O |
O |
|||
6soz | 3 | P02787 | 100.0 | 0.0 |
X-RAY |
2019-11-06 | TYR | C:83 | C:85 | 31.0 | 0.135 | -126.0 | 145.1 | 31.0 | 0.135 | 0.0 | |||||||
2hav | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2006-06-27 | TYR | A:82 | A:85 | 43.0 | 0.187 | -128.7 | 42.6 | 43.0 | 0.187 | 0.0 |
CIT |
7.312 |
OH |
O1 |
|||
TYR | B:82 | B:85 | 34.0 | 0.148 | -118.7 | -35.8 | NA | NA | NA | ||||||||||||||
3s9l | 2 | P02787 | 99.41 | 0.0 |
X-RAY |
2011-08-10 | TYR | C:99 | C:85 | 7.0 | 0.03 | E | -113.3 | 153.8 | 7.0 | 0.03 | 0.0 |
FE CO3 |
5.683 6.893 |
OH OH |
FE O2 |
||
TYR | D:99 | D:85 | 30.0 | 0.13 | E | -102.6 | 132.5 | NA | NA | NA | |||||||||||||
3s9m | 2 | P02787 | 99.41 | 0.0 |
X-RAY |
2011-08-10 | TYR | C:99 | C:85 | 10.0 | 0.043 | E | -109.2 | 146.5 | 10.0 | 0.043 | 0.0 |
CO3 FE |
7.132 5.473 |
OH OH |
O2 FE |
||
TYR | D:99 | D:85 | 33.0 | 0.143 | E | -103.8 | 135.6 | NA | NA | NA | |||||||||||||
3s9n | 2 | P02787 | 99.41 | 0.0 |
X-RAY |
2011-08-10 | TYR | C:99 | C:85 | 5.0 | 0.022 | E | -113.5 | 169.2 | 5.0 | 0.022 | 0.0 |
FE CO3 |
6.156 8.125 |
OH OH |
FE O1 |
||
TYR | D:99 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
2hau | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2006-06-27 | TYR | A:82 | A:85 | 36.0 | 0.157 | S | -129.2 | 43.0 | 36.0 | 0.157 | 0.0 | ||||||
TYR | B:82 | B:85 | 46.0 | 0.2 | S | -130.5 | 2.5 | NA | NA | NA | |||||||||||||
1bp5 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1999-01-13 | TYR | A:85 | A:85 | 31.0 | 0.135 | E | -140.7 | 178.6 | 31.0 | 0.135 | 0.0 |
HOH |
3.699 |
CD1 |
O |
||
TYR | B:85 | B:85 | 31.0 | 0.135 | E | -136.0 | 179.0 | NA | NA | NA | |||||||||||||
TYR | C:85 | C:85 | 28.0 | 0.122 | B | -141.5 | 178.5 | NA | NA | NA | |||||||||||||
TYR | D:85 | D:85 | 27.0 | 0.117 | B | -134.7 | -178.6 | NA | NA | NA | |||||||||||||
1btj | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1999-01-13 | TYR | A:85 | A:85 | 29.0 | 0.126 | B | -134.2 | 172.7 | 29.0 | 0.126 | 0.0 | ||||||
TYR | B:85 | B:85 | 27.0 | 0.117 | E | -135.6 | 172.6 | NA | NA | NA | |||||||||||||
2o84 | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2007-01-23 | TYR | A:85 | X:85 | 6.0 | 0.026 | E | -124.7 | 174.9 | 6.0 | 0.026 | 0.0 |
FE CO3 HOH |
6.525 8.461 3.905 |
OH OH CB |
FE O1 O |
||
2o7u | 1 | P02787 | 99.41 | 0.0 |
X-RAY |
2007-01-23 | TYR | A:85 | B:85 | 7.0 | 0.03 | E | -113.8 | -161.0 | 7.0 | 0.03 | 0.0 |
FE CO3 HOH |
6.215 8.047 3.213 |
OH OH CE1 |
FE O3 O |
||
TYR | B:85 | A:85 | 8.0 | 0.035 | E | -117.0 | -164.6 | NA | NA | NA | |||||||||||||
TYR | C:85 | C:85 | 7.0 | 0.03 | E | -114.1 | -161.9 | NA | NA | NA | |||||||||||||
TYR | D:85 | D:85 | 5.0 | 0.022 | E | -121.1 | -173.1 | NA | NA | NA | |||||||||||||
TYR | E:85 | E:85 | 5.0 | 0.022 | E | -120.0 | -173.7 | NA | NA | NA | |||||||||||||
TYR | F:85 | F:85 | 4.0 | 0.017 | E | -119.2 | -174.0 | NA | NA | NA | |||||||||||||
TYR | G:85 | G:85 | 4.0 | 0.017 | E | -121.5 | -172.5 | NA | NA | NA | |||||||||||||
TYR | H:85 | H:85 | 5.0 | 0.022 | E | -122.9 | -172.1 | NA | NA | NA | |||||||||||||
TYR | I:85 | I:85 | 4.0 | 0.017 | E | -121.3 | -172.0 | NA | NA | NA | |||||||||||||
3fgs | 1 | P02787 | 99.41 | 0.0 |
X-RAY |
2009-05-19 | TYR | A:85 | A:85 | 2.0 | 0.009 | B | -128.1 | -169.8 | 2.0 | 0.009 | 0.0 |
CO3 FE HOH |
8.566 6.518 3.466 |
OH OH CB |
O1 FE O |
||
1oqg | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | TYR | A:85 | A:85 | 3.0 | 0.013 | E | -122.3 | -169.5 | 3.0 | 0.013 | 0.0 |
CO3 FE HOH |
8.303 6.557 3.218 |
OH OH CB |
O2 FE O |
||
1oqh | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | TYR | A:85 | A:85 | 3.0 | 0.013 | E | -119.2 | -171.3 | 3.0 | 0.013 | 0.0 |
CO3 FE HOH |
7.938 6.290 3.513 |
OH OH CB |
O2 FE O |
||
1jqf | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2001-10-17 | TYR | A:85 | A:85 | 3.0 | 0.013 | E | -121.5 | -168.5 | 3.0 | 0.013 | 0.0 |
CO3 FE HOH |
8.366 6.508 3.282 |
OH OH CB |
O3 FE O |
||
1dtg | 1 | P02787 | 99.4 | 0.0 |
X-RAY |
2000-01-21 | TYR | A:85 | A:85 | 6.0 | 0.026 | E | -124.8 | -175.5 | 6.0 | 0.026 | 0.0 |
FE CO3 HOH |
6.207 7.893 3.270 |
OH OH CB |
FE O2 O |
||
1n84 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2003-03-18 | TYR | A:85 | A:85 | 3.0 | 0.013 | E | -119.5 | -176.8 | 3.0 | 0.013 | 0.0 |
CO3 FE HOH |
7.935 6.282 3.206 |
OH OH CB |
O2 FE O |
||
1fqe | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2001-05-16 | TYR | A:85 | A:85 | 4.0 | 0.017 | B | -125.2 | -174.2 | 4.0 | 0.017 | 0.0 |
FE CO3 HOH |
6.780 8.659 3.306 |
OH OH CB |
FE O3 O |
||
1fqf | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2001-05-16 | TYR | A:85 | A:85 | 5.0 | 0.022 | E | -114.8 | -169.9 | 5.0 | 0.022 | 0.0 |
FE CO3 HOH |
6.046 7.777 3.011 |
OH OH OH |
FE O3 O |
||
1n7x | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | TYR | A:85 | A:85 | 4.0 | 0.017 | E | -121.8 | -174.8 | 4.0 | 0.017 | 0.0 |
CO3 FE HOH |
7.833 6.248 3.278 |
OH OH CB |
O1 FE O |
||
1b3e | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
1999-03-26 | TYR | A:82 | A:85 | 7.0 | 0.03 | E | -114.0 | 175.6 | 7.0 | 0.03 | 0.0 |
FE CO3 HOH |
6.232 7.964 3.331 |
OH OH CB |
FE O2 O |
||
1a8e | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1998-06-17 | TYR | A:83 | A:85 | 4.0 | 0.017 | B | -121.0 | -175.7 | 4.0 | 0.017 | 0.0 |
CO3 FE HOH |
7.508 6.388 3.115 |
OH OH CB |
O2 FE O |
||
1a8f | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1998-06-17 | TYR | A:83 | A:85 | 4.0 | 0.017 | E | -119.9 | 175.2 | 4.0 | 0.017 | 0.0 |
CO3 FE HOH |
7.345 6.379 3.211 |
OH OH CB |
O2 FE O |
||
1suv | 2 | P02787 | 100.0 | 0.0 |
EM |
2004-04-13 | TYR | C:83 | C:85 | 4.0 | 0.017 | B | -121.0 | -175.7 | 4.0 | 0.017 | 0.0 |
CO3 FE |
7.508 6.389 |
OH OH |
O2 FE |
||
TYR | D:83 | D:85 | 4.0 | 0.017 | B | -121.0 | -175.7 | 4.0 | 0.017 | 0.0 |
CO3 FE |
7.508 6.388 |
OH OH |
O2 FE |
|||||||||
1d3k | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2000-03-01 | TYR | A:83 | A:85 | 4.0 | 0.017 | B | -120.8 | -170.2 | 4.0 | 0.017 | 0.0 |
CO3 FE HOH |
8.197 6.432 3.480 |
OH OH CB |
O1 FE O |
||
1d4n | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2000-03-01 | TYR | A:83 | A:85 | 3.0 | 0.013 | B | -120.3 | -170.0 | 3.0 | 0.013 | 0.0 |
CO3 FE HOH |
8.310 6.364 3.325 |
OH OH CB |
O1 FE O |
||
1n7w | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | TYR | A:85 | A:85 | 5.0 | 0.022 | E | -120.4 | 179.5 | 5.0 | 0.022 | 0.0 |
CO3 FE HOH |
8.447 6.376 3.487 |
OH OH CB |
O1 FE O |
||
1ryo | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2004-05-11 | TYR | A:85 | A:85 | 3.0 | 0.013 | E | -119.1 | -174.8 | 3.0 | 0.013 | 0.0 |
OXL FE HOH |
7.739 6.366 3.265 |
OH OH CB |
O1 FE O |
||
1tfd | 1 | P19134 | 82.57 | 0.0 |
X-RAY |
1993-04-15 | TYR | A:85 | A:85 | 12.0 | 0.052 | -62.4 | 31.0 | 12.0 | 0.052 | 0.0 |
CO3 FE |
7.787 6.187 |
OH OH |
O3 FE |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p02787-f1 | 1 | P02787 | 99.86 | 0.0 | TYR | A:104 | A:104 | 10.0 | 0.043 | E | -113.3 | -178.3 |