Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 133476629 | . | A | C | CCDS3080.1:NM_001063.3:c.887gAc>gCc_NP_001054.1:p.296D>A | Homo sapiens transferrin (TF), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3v83 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2012-02-15 | ASP | A:296 | A:277 | 95.0 | 0.633 | T | -83.7 | 3.2 | 95.0 | 0.633 | 0.0 |
HOH |
5.822 |
N |
O |
||
ASP | B:296 | B:277 | 159.0 | 1.0 | T | 55.8 | 24.2 | NA | NA | NA | |||||||||||||
ASP | C:296 | C:277 | 162.0 | 1.0 | T | 66.2 | 17.5 | NA | NA | NA | |||||||||||||
ASP | D:296 | D:277 | 167.0 | 1.0 | T | 61.0 | 24.9 | NA | NA | NA | |||||||||||||
ASP | E:296 | E:277 | 163.0 | 1.0 | T | 61.2 | 17.4 | NA | NA | NA | |||||||||||||
ASP | F:296 | F:277 | 135.0 | 0.9 | T | -117.7 | 53.1 | NA | NA | NA | |||||||||||||
3v8x | 2 | P02787 | 100.0 | 0.0 |
X-RAY |
2012-02-29 | ASP | B:296 | B:277 | 24.0 | NA | T | 178.3 | 62.3 | 24.0 | NA | NA | ||||||
6d03 | 2 | P02787 | 100.0 | 0.0 |
EM |
2018-06-20 | ASP | C:296 | C:277 | 127.0 | 0.847 | S | 58.0 | 25.6 | 127.0 | 0.847 | 0.0 | ||||||
ASP | D:296 | D:277 | 89.0 | 0.593 | S | 35.2 | 42.7 | 89.0 | 0.593 | 0.0 | |||||||||||||
6d04 | 2 | P02787 | 100.0 | 0.0 |
EM |
2018-06-20 | ASP | C:296 | C:277 | 104.0 | 0.693 | S | 37.6 | 38.7 | 104.0 | 0.693 | 0.0 | ||||||
ASP | D:296 | D:277 | 104.0 | 0.693 | S | 37.6 | 38.6 | 104.0 | 0.693 | 0.0 | |||||||||||||
6d05 | 2 | P02787 | 100.0 | 0.0 |
EM |
2018-06-20 | ASP | C:296 | C:277 | 125.0 | 0.833 | S | 65.2 | 35.8 | 125.0 | 0.833 | 0.0 | ||||||
ASP | D:296 | D:277 | 123.0 | 0.82 | S | 65.2 | 35.9 | 123.0 | 0.82 | 0.0 | |||||||||||||
5dyh | 1 | P02787 | 99.86 | 0.0 |
X-RAY |
2016-04-27 | ASP | A:296 | A:277 | 141.0 | 0.94 | T | 59.3 | 22.2 | 141.0 | 0.94 | 0.0 | ||||||
ASP | B:296 | B:277 | 143.0 | 0.953 | T | 59.6 | 23.2 | NA | NA | NA | |||||||||||||
6uj6 | 1 | Q06AH7 | 99.71 | 0.0 |
X-RAY |
2020-09-30 | ASP | A:296 | A:296 | 136.0 | 0.907 | T | 61.0 | 36.5 | 136.0 | 0.907 | 0.0 | ||||||
3qyt | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2012-03-14 | ASP | A:277 | A:277 | 162.0 | 1.0 | S | 58.4 | 18.1 | 162.0 | 1.0 | 0.0 | ||||||
4x1b | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2015-04-08 | ASP | A:277 | A:277 | 125.0 | 0.833 | T | 59.2 | 30.9 | 125.0 | 0.833 | 0.0 |
HOH |
2.869 |
OD1 |
O |
||
4x1d | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2015-04-08 | ASP | A:277 | A:277 | 151.0 | 1.0 | T | 59.5 | 33.4 | 151.0 | 1.0 | 0.0 |
HOH |
2.792 |
N |
O |
||
ASP | B:277 | B:277 | 135.0 | 0.9 | T | 58.5 | 33.1 | NA | NA | NA | |||||||||||||
5h52 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2017-11-08 | ASP | A:277 | A:277 | 129.0 | 0.86 | T | 61.2 | 27.7 | 129.0 | 0.86 | 0.0 | ||||||
5wtd | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | ASP | A:277 | A:277 | 130.0 | 0.867 | T | 63.1 | 28.8 | 130.0 | 0.867 | 0.0 |
HOH |
4.404 |
N |
O |
||
6jas | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2020-01-29 | ASP | A:277 | A:277 | 149.0 | 0.993 | T | 60.0 | 35.1 | 149.0 | 0.993 | 0.0 |
HOH |
5.605 |
N |
O |
||
4h0w | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2012-12-26 | ASP | A:277 | A:277 | 156.0 | 1.0 | T | 61.0 | 17.2 | 156.0 | 1.0 | 0.0 |
HOH |
6.123 |
N |
O |
||
5x5p | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2018-02-21 | ASP | A:277 | A:277 | 156.0 | 1.0 | T | 54.6 | 37.0 | 156.0 | 1.0 | 0.0 | ||||||
5y6k | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2018-01-24 | ASP | A:277 | A:277 | 153.0 | 1.0 | T | 54.3 | 48.8 | 153.0 | 1.0 | 0.0 | ||||||
6ctc | 1 | P02787 | 99.85 | 0.0 |
X-RAY |
2018-10-24 | ASP | A:277 | A:277 | 167.0 | 1.0 | T | 59.4 | 56.1 | 167.0 | 1.0 | 0.0 |
HOH |
5.851 |
N |
O |
||
3ve1 | 2 | P02787 | 99.71 | 0.0 |
X-RAY |
2012-02-22 | ASP | B:277 | B:277 | 164.0 | 1.0 | T | 66.3 | -3.9 | 164.0 | 1.0 | 0.0 |
HOH |
8.302 |
O |
O |
||
ASP | D:277 | D:277 | 161.0 | 1.0 | T | 66.3 | -3.5 | NA | NA | NA | |||||||||||||
6soy | 3 | P02787 | 100.0 | 0.0 |
X-RAY |
2019-11-06 | ASP | C:275 | C:277 | 161.0 | 1.0 | T | 54.7 | 48.5 | 161.0 | 1.0 | 0.0 | ||||||
6soz | 3 | P02787 | 100.0 | 0.0 |
X-RAY |
2019-11-06 | ASP | C:275 | C:277 | 154.0 | 1.0 | T | 58.1 | 50.9 | 154.0 | 1.0 | 0.0 | ||||||
2hav | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2006-06-27 | ASP | A:274 | A:277 | 145.0 | 0.967 | S | -148.7 | -34.8 | 145.0 | 0.967 | 0.0 | ||||||
ASP | B:274 | B:277 | 150.0 | 1.0 | T | 42.9 | 64.0 | NA | NA | NA | |||||||||||||
3s9l | 2 | P02787 | 99.41 | 0.0 |
X-RAY |
2011-08-10 | ASP | C:291 | C:277 | 160.0 | 1.0 | T | 56.9 | 43.6 | 160.0 | 1.0 | 0.0 | ||||||
ASP | D:291 | D:277 | 168.0 | 1.0 | T | 54.6 | 48.7 | NA | NA | NA | |||||||||||||
3s9m | 2 | P02787 | 99.41 | 0.0 |
X-RAY |
2011-08-10 | ASP | C:291 | C:277 | 166.0 | 1.0 | S | 36.2 | 49.2 | 166.0 | 1.0 | 0.0 | ||||||
ASP | D:291 | D:277 | 178.0 | 1.0 | T | 51.7 | 55.5 | NA | NA | NA | |||||||||||||
3s9n | 2 | P02787 | 99.41 | 0.0 |
X-RAY |
2011-08-10 | ASP | C:291 | C:277 | 171.0 | 1.0 | T | 52.1 | 50.5 | 171.0 | 1.0 | 0.0 | ||||||
ASP | D:291 | D:277 | 111.0 | NA | S | 54.0 | 76.8 | NA | NA | NA | |||||||||||||
2hau | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2006-06-27 | ASP | A:274 | A:277 | 140.0 | 0.933 | T | 62.2 | -2.8 | 140.0 | 0.933 | 0.0 | ||||||
ASP | B:274 | B:277 | 118.0 | 0.787 | S | 53.2 | 85.7 | NA | NA | NA | |||||||||||||
1bp5 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1999-01-13 | ASP | A:277 | A:277 | 162.0 | 1.0 | T | 78.1 | -27.2 | 162.0 | 1.0 | 0.0 |
HOH |
3.867 |
O |
O |
||
ASP | B:277 | B:277 | 167.0 | 1.0 | T | 75.9 | -10.1 | NA | NA | NA | |||||||||||||
ASP | C:277 | C:277 | 148.0 | 0.987 | T | 58.2 | 47.1 | NA | NA | NA | |||||||||||||
ASP | D:277 | D:277 | 158.0 | 1.0 | T | 54.6 | 62.6 | NA | NA | NA | |||||||||||||
1btj | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1999-01-13 | ASP | A:277 | A:277 | 134.0 | 0.893 | T | 65.5 | 52.2 | 134.0 | 0.893 | 0.0 | ||||||
ASP | B:277 | B:277 | 137.0 | 0.913 | T | 61.8 | 49.1 | NA | NA | NA | |||||||||||||
2o84 | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2007-01-23 | ASP | A:277 | X:277 | 162.0 | 1.0 | T | 68.8 | 9.8 | 162.0 | 1.0 | 0.0 |
HOH |
4.566 |
C |
O |
||
2o7u | 1 | P02787 | 99.41 | 0.0 |
X-RAY |
2007-01-23 | ASP | A:277 | B:277 | 149.0 | 0.993 | T | 21.8 | 61.8 | 149.0 | 0.993 | 0.0 | ||||||
ASP | B:277 | A:277 | 148.0 | 0.987 | T | 24.2 | 62.9 | NA | NA | NA | |||||||||||||
ASP | C:277 | C:277 | 147.0 | 0.98 | T | 22.8 | 63.7 | NA | NA | NA | |||||||||||||
ASP | D:277 | D:277 | 157.0 | 1.0 | T | 59.5 | 22.7 | NA | NA | NA | |||||||||||||
ASP | E:277 | E:277 | 155.0 | 1.0 | T | 58.4 | 22.4 | NA | NA | NA | |||||||||||||
ASP | F:277 | F:277 | 157.0 | 1.0 | T | 56.4 | 23.1 | NA | NA | NA | |||||||||||||
ASP | G:277 | G:277 | 157.0 | 1.0 | T | 58.4 | 21.7 | NA | NA | NA | |||||||||||||
ASP | H:277 | H:277 | 154.0 | 1.0 | T | 58.2 | 21.6 | NA | NA | NA | |||||||||||||
ASP | I:277 | I:277 | 155.0 | 1.0 | T | 58.1 | 22.3 | NA | NA | NA | |||||||||||||
3fgs | 1 | P02787 | 99.41 | 0.0 |
X-RAY |
2009-05-19 | ASP | A:277 | A:277 | 158.0 | 1.0 | T | 57.5 | 17.2 | 158.0 | 1.0 | 0.0 |
HOH |
2.568 |
OD1 |
O |
||
1oqg | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | ASP | A:277 | A:277 | 168.0 | 1.0 | T | 62.4 | 11.1 | 168.0 | 1.0 | 0.0 |
HOH |
3.195 |
N |
O |
||
1oqh | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | ASP | A:277 | A:277 | 159.0 | 1.0 | T | 64.2 | 13.9 | 159.0 | 1.0 | 0.0 |
HOH |
3.371 |
CA |
O |
||
1jqf | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2001-10-17 | ASP | A:277 | A:277 | 162.0 | 1.0 | T | 62.0 | 13.9 | 162.0 | 1.0 | 0.0 |
HOH |
3.152 |
CA |
O |
||
1dtg | 1 | P02787 | 99.4 | 0.0 |
X-RAY |
2000-01-21 | ASP | A:277 | A:277 | 151.0 | 1.0 | T | 60.2 | 26.3 | 151.0 | 1.0 | 0.0 |
HOH |
8.479 |
OD2 |
O |
||
1n84 | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2003-03-18 | ASP | A:277 | A:277 | 154.0 | 1.0 | T | 61.6 | 13.0 | 154.0 | 1.0 | 0.0 |
HOH |
4.363 |
C |
O |
||
1fqe | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2001-05-16 | ASP | A:277 | A:277 | 164.0 | 1.0 | T | 63.5 | 14.6 | 164.0 | 1.0 | 0.0 |
HOH |
3.014 |
O |
O |
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1fqf | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2001-05-16 | ASP | A:277 | A:277 | 162.0 | 1.0 | T | 53.4 | 29.3 | 162.0 | 1.0 | 0.0 |
HOH |
2.706 |
N |
O |
||
1n7x | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | ASP | A:277 | A:277 | 165.0 | 1.0 | T | 67.3 | 7.0 | 165.0 | 1.0 | 0.0 |
HOH |
2.985 |
OD2 |
O |
||
1b3e | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
1999-03-26 | ASP | A:274 | A:277 | 159.0 | 1.0 | T | 85.1 | -29.1 | 159.0 | 1.0 | 0.0 |
HOH |
4.523 |
C |
O |
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1a8e | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1998-06-17 | ASP | A:275 | A:277 | 163.0 | 1.0 | T | 63.2 | 17.3 | 163.0 | 1.0 | 0.0 |
HOH |
4.443 |
N |
O |
||
1a8f | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
1998-06-17 | ASP | A:275 | A:277 | 159.0 | 1.0 | T | 56.8 | 23.3 | 159.0 | 1.0 | 0.0 |
HOH |
2.767 |
N |
O |
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1suv | 2 | P02787 | 100.0 | 0.0 |
EM |
2004-04-13 | ASP | C:275 | C:277 | 163.0 | 1.0 | T | 63.2 | 17.3 | 163.0 | 1.0 | 0.0 | ||||||
ASP | D:275 | D:277 | 165.0 | 1.0 | T | 63.2 | 17.3 | 165.0 | 1.0 | 0.0 | |||||||||||||
1d3k | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2000-03-01 | ASP | A:275 | A:277 | 161.0 | 1.0 | T | 58.3 | 25.2 | 161.0 | 1.0 | 0.0 |
HOH |
4.289 |
N |
O |
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1d4n | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2000-03-01 | ASP | A:275 | A:277 | 168.0 | 1.0 | T | 61.0 | 21.3 | 168.0 | 1.0 | 0.0 |
HOH |
4.484 |
N |
O |
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1n7w | 1 | P02787 | 99.7 | 0.0 |
X-RAY |
2003-03-18 | ASP | A:277 | A:277 | 154.0 | 1.0 | T | 56.2 | 28.7 | 154.0 | 1.0 | 0.0 |
HOH |
3.097 |
CA |
O |
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1ryo | 1 | P02787 | 100.0 | 0.0 |
X-RAY |
2004-05-11 | ASP | A:277 | A:277 | 156.0 | 1.0 | T | 59.0 | 30.2 | 156.0 | 1.0 | 0.0 |
HOH |
2.957 |
N |
O |
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1tfd | 1 | P19134 | 82.57 | 0.0 |
X-RAY |
1993-04-15 | ASP | A:277 | A:277 | 169.0 | 1.0 | S | -89.8 | 84.0 | 169.0 | 1.0 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p02787-f1 | 1 | P02787 | 99.86 | 0.0 | ASP | A:296 | A:296 | 144.0 | 0.96 | T | 61.2 | 20.8 |