Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 183899979 | . | T | A | CCDS43177.1:NM_004068.3:c.1004gTg>gAg_NP_004059.2:p.335V>E | Homo sapiens adaptor related protein complex 2 mu 1 subunit (AP2M1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2bp5 | 1 | P84092 | 100.0 | 0.0 |
X-RAY |
2005-07-06 | VAL | A:335 | M:335 | 46.0 | 0.297 | E | -124.4 | 145.9 | 46.0 | 0.297 | 0.0 |
HOH |
3.118 |
O |
O |
||
| 2jkr | 4 | P84092 | 100.0 | 0.0 |
X-RAY |
2008-10-28 | VAL | F:335 | M:335 | 49.0 | 0.316 | -111.0 | 170.9 | 1.0 | 0.006 | 0.31 |
A:P17427:0.31 |
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| VAL | J:335 | U:335 | 49.0 | 0.316 | -115.3 | 171.9 | NA | NA | NA | ||||||||||||||
| 2jkt | 4 | P84092 | 100.0 | 0.0 |
X-RAY |
2008-10-28 | VAL | F:335 | M:335 | 47.0 | 0.303 | -126.7 | 177.1 | 1.0 | 0.006 | 0.297 |
A:P17427:0.297 |
HOH |
7.899 |
O |
O |
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| VAL | J:335 | U:335 | 49.0 | 0.316 | -127.6 | 177.7 | NA | NA | NA | ||||||||||||||
| 2vgl | 3 | P84092 | 100.0 | 0.0 |
X-RAY |
2007-12-25 | VAL | C:335 | M:335 | 44.0 | 0.284 | E | -103.4 | 142.5 | 44.0 | 0.284 | 0.0 | ||||||
| 6owo | 3 | P84091 | 100.0 | 0.0 |
EM |
2019-09-11 | VAL | C:335 | M:335 | 41.0 | 0.265 | E | -114.5 | 126.1 | 41.0 | 0.265 | 0.0 | ||||||
| 6yae | 3 | P84092 | 100.0 | 0.0 |
EM |
2020-07-29 | VAL | C:335 | M:335 | 51.0 | 0.329 | E | -132.5 | 142.6 | 51.0 | 0.329 | 0.0 | ||||||
| 6oxl | 3 | P84091 | 99.77 | 0.0 |
EM |
2019-09-11 | VAL | C:335 | M:335 | 35.0 | 0.226 | E | -85.8 | 124.1 | 35.0 | 0.226 | 0.0 | ||||||
| 2xa7 | 3 | P84092 | 97.53 | 0.0 |
X-RAY |
2010-07-21 | VAL | C:346 | M:346 | 54.0 | 0.348 | E | -108.5 | 137.1 | 54.0 | 0.348 | 0.0 | ||||||
| 4uqi | 3 | P84092 | 97.53 | 0.0 |
X-RAY |
2014-07-30 | VAL | C:346 | M:335 | 47.0 | 0.303 | E | -115.5 | 131.2 | 47.0 | 0.303 | 0.0 | ||||||
| 5fpi | 1 | P84092 | 97.53 | 0.0 |
X-RAY |
2016-01-20 | VAL | A:346 | A:335 | 41.0 | 0.265 | E | -132.7 | 139.4 | 41.0 | 0.265 | 0.0 |
HOH |
3.652 |
O |
O |
||
| 6qh5 | 3 | P84092 | 97.53 | 0.0 |
X-RAY |
2019-09-04 | VAL | C:346 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6qh5 | 4 | P84092 | 97.53 | 0.0 |
X-RAY |
2019-09-04 | VAL | D:346 | M:335 | 44.0 | 0.284 | E | -130.3 | 131.7 | 44.0 | 0.284 | 0.0 | ||||||
| 6qh6 | 3 | Q3ZC13 | 97.53 | 0.0 |
X-RAY |
2019-09-04 | VAL | C:346 | M:346 | 43.0 | 0.277 | E | -137.5 | 136.4 | 43.0 | 0.277 | 0.0 | ||||||
| 6qh6 | 4 | P84092 | 97.53 | 0.0 |
X-RAY |
2019-09-04 | VAL | D:346 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6qh7 | 3 | Q3ZC13 | 97.53 | 0.0 |
X-RAY |
2019-09-04 | VAL | C:346 | M:346 | 43.0 | 0.277 | E | -140.4 | 139.5 | 43.0 | 0.277 | 0.0 | ||||||
| VAL | D:346 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6yaf | 3 | P84092 | 97.53 | 0.0 |
EM |
2020-07-29 | VAL | C:346 | M:346 | 109.0 | 0.703 | -105.8 | 142.2 | 109.0 | 0.703 | 0.0 | |||||||
| 6yah | 3 | P84092 | 97.53 | 0.0 |
EM |
2020-07-29 | VAL | C:346 | M:346 | 109.0 | 0.703 | -105.9 | 142.2 | 109.0 | 0.703 | 0.0 | |||||||
| 1bw8 | 1 | P84092 | 99.37 | 0.0 |
X-RAY |
1998-11-25 | VAL | A:221 | A:335 | 46.0 | 0.297 | E | -129.1 | 153.2 | 46.0 | 0.297 | 0.0 |
HOH |
4.025 |
O |
O |
||
| 1i31 | 1 | P84092 | 100.0 | 0.0 |
X-RAY |
2001-02-21 | VAL | A:214 | A:335 | 46.0 | 0.297 | E | -125.8 | 147.8 | 46.0 | 0.297 | 0.0 |
HOH |
3.833 |
O |
O |
||
| 2pr9 | 1 | P84092 | 94.59 | 0.0 |
X-RAY |
2008-03-18 | VAL | A:199 | A:335 | 48.0 | 0.31 | E | -138.5 | 152.9 | 48.0 | 0.31 | 0.0 |
HOH |
3.766 |
O |
O |
||
| 3h85 | 1 | P84092 | 94.59 | 0.0 |
X-RAY |
2009-11-24 | VAL | A:199 | A:335 | 47.0 | 0.303 | E | -144.4 | 134.0 | 47.0 | 0.303 | 0.0 |
HOH |
7.295 |
CA |
O |
||
| 5wrl | 1 | P84092 | 100.0 | 0.0 |
X-RAY |
2017-12-06 | VAL | A:178 | A:335 | 47.0 | 0.303 | E | -139.8 | 153.0 | 47.0 | 0.303 | 0.0 | ||||||
| 5wrm | 1 | P84092 | 100.0 | 0.0 |
X-RAY |
2017-12-06 | VAL | A:178 | A:335 | 45.0 | 0.29 | E | -128.8 | 149.6 | 45.0 | 0.29 | 0.0 |
HOH |
3.889 |
O |
O |
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| 1bxx | 1 | P84092 | 100.0 | 0.0 |
X-RAY |
1998-11-25 | VAL | A:185 | A:335 | 48.0 | 0.31 | E | -129.9 | 148.3 | 48.0 | 0.31 | 0.0 |
HOH |
3.751 |
O |
O |
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| 1hes | 1 | P20172 | 100.0 | 0.0 |
X-RAY |
2001-05-31 | VAL | A:185 | A:335 | 44.0 | 0.284 | E | -140.0 | 151.1 | 44.0 | 0.284 | 0.0 |
HOH |
6.319 |
CG2 |
O |
||
| 6bnt | 1 | Q96CW1 | 99.28 | 0.0 |
X-RAY |
2018-11-21 | VAL | A:215 | A:335 | 44.0 | 0.284 | E | -134.7 | 155.9 | 44.0 | 0.284 | 0.0 |
HOH |
7.157 |
N |
O |
||
| 5c7z | 1 | P84092 | 96.18 | 0.0 |
X-RAY |
2016-07-06 | VAL | A:188 | A:335 | 41.0 | 0.265 | E | -132.7 | 139.4 | 41.0 | 0.265 | 0.0 |
HOH |
3.652 |
O |
O |
||
| 1h6e | 1 | P20172 | 93.56 | 0.0 |
X-RAY |
2001-11-28 | VAL | A:188 | A:335 | 43.0 | 0.277 | E | -154.2 | 149.0 | 43.0 | 0.277 | 0.0 | ||||||
| 3ml6 | 1 | Q60838,P84092 | 100.0 | 0.0 |
X-RAY |
2010-08-11 | VAL | A:285 | A:1335 | 49.0 | 0.316 | E | -114.2 | 153.7 | 49.0 | 0.316 | 0.0 | ||||||
| VAL | B:285 | B:1335 | 46.0 | 0.297 | E | -116.0 | 156.1 | NA | NA | NA | |||||||||||||
| VAL | C:285 | C:1335 | 41.0 | 0.265 | E | -115.1 | 155.4 | NA | NA | NA | |||||||||||||
| VAL | D:285 | D:1335 | 50.0 | 0.323 | E | -117.0 | 152.9 | NA | NA | NA | |||||||||||||
| VAL | E:285 | E:1335 | 48.0 | 0.31 | E | -115.5 | 153.2 | NA | NA | NA | |||||||||||||
| VAL | F:285 | F:1335 | 51.0 | 0.329 | E | -114.4 | 154.9 | NA | NA | NA | |||||||||||||
| 5wrk | 1 | P84092 | 86.69 | 1e-172 |
X-RAY |
2017-12-06 | VAL | A:178 | A:335 | 47.0 | 0.303 | E | -129.1 | 147.2 | 47.0 | 0.303 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q96cw1-f1 | 1 | Q96CW1 | 100.0 | 0.0 | VAL | A:335 | A:335 | 47.0 | 0.303 | E | -130.0 | 131.6 | |