Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 187449691 . G A CCDS3289.1:NM_001130845.1:c.189gaC>gaT_NP_001124317.1:p.63D>D Homo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6xmx 1 P41182 99.72 0.0 EM
 2020-11-25 ASP A:103 A:63 63.0 0.42 S -65.4 126.0 53.0 0.353 0.067 E:P41182:0.067
 U52
 9.812
 H
 H6
ASP B:103 B:63 66.0 0.44 S -65.4 126.0 52.0 0.347 0.093 D:P41182:0.093
 U52
 9.806
 H
 H6
ASP C:103 C:63 62.0 0.413 S -65.4 126.0 54.0 0.36 0.053 A:P41182:0.053
 U52
 9.794
 H
 H6
ASP D:103 D:63 62.0 0.413 S -65.4 126.0 62.0 0.413 0.0 U52
 9.809
 H
 H6
ASP E:103 E:63 62.0 0.413 S -65.5 126.0 53.0 0.353 0.06 G:P41182:0.06
 U52
 9.798
 H
 H6
ASP F:103 F:63 61.0 0.407 S -65.4 126.0 51.0 0.34 0.067 B:P41182:0.067
 U52
 9.802
 H
 H6
ASP G:103 G:63 64.0 0.427 S -65.4 126.0 64.0 0.427 0.0 U52
 9.808
 H
 H6
ASP H:103 H:63 63.0 0.42 S -65.4 126.0 55.0 0.367 0.053 F:P41182:0.053
 U52
 9.797
 H
 H6
5h7g 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 ASP A:75 A:63 61.0 0.407 S -85.0 128.0 61.0 0.407 0.0 HOH
 6.288
 O
 O
ASP B:75 B:63 57.0 0.38 S -87.7 120.0 57.0 0.38 0.0 HOH
 8.761
 OD2
 O
5h7h 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 ASP A:75 A:63 63.0 0.42 S -79.2 128.2 63.0 0.42 0.0 HOH
 3.567
 CA
 O
5x4m 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ASP A:75 A:63 51.0 0.34 S -85.7 127.5 51.0 0.34 0.0 HOH
 3.734
 N
 O
5x4n 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ASP A:75 A:63 57.0 0.38 S -80.1 125.4 57.0 0.38 0.0 HOH
 3.786
 N
 O
5x4o 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ASP A:75 A:63 61.0 0.407 S -79.8 127.4 61.0 0.407 0.0 HOH
 5.805
 N
 O
5x4p 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ASP A:75 A:63 57.0 0.38 S -79.8 123.3 57.0 0.38 0.0
5x4q 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ASP A:75 A:63 61.0 0.407 S -79.3 126.8 61.0 0.407 0.0 HOH
 2.690
 OD1
 O
5x9o 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 ASP A:75 A:63 62.0 0.413 S -82.9 129.7 62.0 0.413 0.0 HOH
 3.622
 N
 O
5x9p 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 ASP A:75 A:63 54.0 0.36 S -76.2 123.1 54.0 0.36 0.0 HOH
 3.646
 N
 O
6toj 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 ASP A:78 A:63 64.0 0.427 S -80.2 126.3 64.0 0.427 0.0 HOH
 2.818
 OD1
 O
6tol 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 ASP A:78 A:63 65.0 0.433 S -81.0 128.1 65.0 0.433 0.0 HOH
 3.467
 CA
 O
6tom 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 ASP A:78 A:63 65.0 0.433 S -83.8 127.1 65.0 0.433 0.0 HOH
 2.915
 OD1
 O
7okd 1 P41182 100.0 1e-85 X-RAY
 2021-12-08 ASP A:78 A:63 67.0 0.447 S -77.6 126.0 67.0 0.447 0.0 HOH
 2.869
 OD1
 O
6tof 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ASP A:62 A:63 57.0 0.38 S -79.8 131.4 57.0 0.38 0.0 EDO
EDO
HOH
 9.793
2.739
3.452
 OD2
OD1
CB
 C1
O1
O
6tog 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ASP A:62 A:63 62.0 0.413 S -90.2 122.9 62.0 0.413 0.0 HOH
 3.950
 CA
 O
6toh 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ASP A:62 A:63 59.0 0.393 S -76.1 132.6 59.0 0.393 0.0 EDO
HOH
 9.740
2.708
 OD2
OD2
 C1
O
6toi 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ASP A:62 A:63 59.0 0.393 S -79.6 133.0 59.0 0.393 0.0 HOH
 3.608
 N
 O
6tok 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ASP A:62 A:63 63.0 0.42 S -75.9 132.5 63.0 0.42 0.0 EDO
HOH
 8.120
2.707
 N
OD2
 C2
O
6ton 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ASP A:62 A:63 59.0 0.393 S -80.9 118.6 59.0 0.393 0.0 EDO
HOH
 9.361
2.793
 OD1
OD2
 C2
O
6too 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ASP A:62 A:63 61.0 0.407 S -74.9 132.7 61.0 0.407 0.0 HOH
 3.052
 OD1
 O
7oke 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 61.0 0.407 S -72.8 135.1 61.0 0.407 0.0 HOH
 2.702
 OD2
 O
7okf 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 58.0 0.387 S -73.2 135.0 58.0 0.387 0.0 EDO
EDO
HOH
 2.849
5.697
3.078
 OD1
N
OD1
 O1
O1
O
7okg 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 63.0 0.42 S -75.5 137.5 63.0 0.42 0.0 EDO
HOH
 2.853
3.713
 OD1
N
 O1
O
7okh 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 61.0 0.407 S -74.5 134.5 61.0 0.407 0.0 HOH
 2.701
 OD2
 O
7oki 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 60.0 0.4 S -76.5 133.4 60.0 0.4 0.0 HOH
 2.707
 OD2
 O
7okj 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 63.0 0.42 S -73.1 136.5 63.0 0.42 0.0 EDO
HOH
 8.129
2.745
 O
OD2
 C2
O
7okk 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 62.0 0.413 S -74.5 127.8 62.0 0.413 0.0 VH8
EDO
HOH
 9.835
9.554
3.545
 N
OD1
N
 N5
C2
O
7okl 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 63.0 0.42 S -71.2 134.5 63.0 0.42 0.0 HOH
 2.734
 OD1
 O
7okm 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ASP A:62 A:63 63.0 0.42 S -73.5 134.2 63.0 0.42 0.0 EDO
HOH
 2.911
2.961
 OD1
OD1
 O2
O
3e4u 1 P41182 100.0 2e-85 X-RAY
 2008-12-09 ASP A:64 A:63 72.0 0.48 -67.7 109.7 72.0 0.48 0.0 HOH
 2.623
 OD2
 O
ASP B:64 B:63 59.0 0.393 -94.2 124.8 59.0 0.393 0.0 HOH
 4.886
 O
 O
ASP C:64 C:63 77.0 0.513 -89.7 121.4 NA NA NA
ASP D:64 D:63 60.0 0.4 -103.1 105.5 NA NA NA
ASP E:64 NA:NA DO NA DO DO DO NA NA NA
ASP F:64 F:63 173.0 1.0 -96.7 360.0 NA NA NA
4u2m 1 Q13105,P41182 99.21 3e-83 X-RAY
 2014-12-10 ASP A:190 A:186 54.0 0.36 -85.2 127.5 54.0 0.36 0.0 HOH
 2.866
 OD2
 O
ASP B:190 B:186 58.0 0.387 -86.1 122.5 NA NA NA
ASP C:190 C:186 57.0 0.38 -86.5 124.5 NA NA NA
ASP D:190 D:186 56.0 0.373 -88.2 122.8 NA NA NA
6c3l 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 ASP A:65 A:63 35.0 NA S -80.9 125.3 35.0 NA NA EGP
HOH
 9.916
3.152
 N
CB
 CAD
O
ASP B:65 B:63 44.0 NA S -82.6 128.1 NA NA NA
6c3n 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 ASP A:65 A:63 54.0 0.36 S -83.4 120.8 54.0 0.36 0.0 HOH
 5.902
 O
 O
ASP B:65 B:63 68.0 0.453 S -65.9 121.4 68.0 0.453 0.0 HOH
 8.157
 OD2
 O
6cq1 1 P41182 96.9 2e-82 X-RAY
 2019-03-20 ASP A:65 A:63 66.0 0.44 S -79.1 122.5 66.0 0.44 0.0 F8J
HOH
 9.850
4.437
 N
CB
 CAF
O
ASP B:65 B:63 69.0 0.46 S -81.7 119.8 69.0 0.46 0.0 F8J
HOH
 9.903
2.639
 N
OD1
 CAF
O
6xwf 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 ASP A:69 A:63 72.0 0.48 S -81.0 125.3 72.0 0.48 0.0 HOH
 2.309
 OD1
 O
6xxs 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 ASP A:69 A:63 59.0 0.393 S -49.8 130.2 59.0 0.393 0.0
ASP B:69 B:63 55.0 0.367 S -73.7 143.5 55.0 0.367 0.0
ASP G:69 F:63 78.0 0.52 S -77.4 140.2 26.0 0.173 0.347 A:P41182:0.347
5mw2 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 ASP A:60 A:63 67.0 0.447 S -65.3 125.5 67.0 0.447 0.0 HOH
 5.207
 O
 O
5mw6 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 ASP A:60 A:63 70.0 0.467 S -68.2 112.2 70.0 0.467 0.0 HOH
 7.607
 O
 O
ASP B:60 B:63 43.0 0.287 -70.4 128.7 43.0 0.287 0.0 HOH
 2.687
 OD2
 O
5mwd 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 ASP A:60 A:63 72.0 0.48 S -73.1 122.7 72.0 0.48 0.0 HOH
 2.715
 OD1
 O
1r28 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 ASP A:61 A:63 67.0 0.447 S -72.9 112.1 67.0 0.447 0.0 HOH
 7.044
 OD2
 O
ASP B:61 B:63 40.0 0.267 -69.9 119.5 40.0 0.267 0.0 HOH
 3.752
 C
 O
1r29 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 ASP A:61 A:63 70.0 0.467 S -82.5 117.1 70.0 0.467 0.0 HOH
 2.613
 OD1
 O
1r2b 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 ASP A:61 A:63 51.0 0.34 S -74.9 109.3 51.0 0.34 0.0 HOH
 5.921
 OD1
 O
ASP B:61 B:63 57.0 0.38 S -74.9 109.3 57.0 0.38 0.0 HOH
 3.721
 CA
 O
3bim 1 P41182 97.6 2e-80 X-RAY
 2008-01-08 ASP A:61 A:63 48.0 0.32 S -64.1 112.5 NA NA NA
ASP C:61 B:63 61.0 0.407 S -83.6 119.9 NA NA NA
ASP E:61 C:63 41.0 0.273 S -74.6 114.2 41.0 0.273 0.0 HOH
 2.550
 OD2
 O
ASP G:61 D:63 58.0 0.387 S -69.8 121.3 58.0 0.387 0.0 HOH
 3.759
 OD2
 O
ASP I:61 E:63 47.0 0.313 -82.1 124.6 NA NA NA
ASP K:61 F:63 44.0 0.293 S -70.4 116.2 NA NA NA
ASP M:61 G:63 59.0 0.393 S -73.3 119.9 NA NA NA
ASP O:61 H:63 53.0 0.353 -97.8 112.6 NA NA NA
3lbz 1 P41182 97.6 2e-80 X-RAY
 2010-04-28 ASP A:61 A:63 53.0 0.353 S -82.4 121.3 53.0 0.353 0.0
ASP B:61 B:63 52.0 0.347 -90.1 118.8 52.0 0.347 0.0 Z89
 5.955
 OD2
 O
7bde 1 P41182 97.6 3e-80 X-RAY
 2021-07-28 ASP A:61 A:63 67.0 0.447 S -63.8 116.0 67.0 0.447 0.0 GOL
HOH
 3.321
4.352
 OD2
C
 O3
O
6ew8 1 P41182 97.58 1e-79 X-RAY
 2018-10-24 ASP A:58 A:63 73.0 0.487 S -71.4 114.1 73.0 0.487 0.0 HOH
 2.753
 OD1
 O
6tbt 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 ASP A:60 A:63 55.0 0.367 S -79.5 124.6 55.0 0.367 0.0 CL
HOH
 8.021
2.885
 O
OD1
 CL
O
ASP B:60 B:63 60.0 0.4 S -73.1 123.4 60.0 0.4 0.0 HOH
 5.434
 O
 O
6tcj 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 ASP A:60 A:63 61.0 0.407 S -78.2 123.2 61.0 0.407 0.0 HOH
 4.946
 O
 O
ASP B:60 B:63 56.0 0.373 S -72.5 119.5 56.0 0.373 0.0 NA
HOH
 9.089
4.903
 OD2
O
 NA
O
6xxs 3 P41182 97.58 1e-79 X-RAY
 2020-12-02 ASP E:60 E:63 61.0 0.407 S -54.3 133.5 61.0 0.407 0.0
6xyx 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 ASP A:60 A:63 62.0 0.413 S -74.4 125.4 62.0 0.413 0.0 HOH
 3.117
 OD1
 O
ASP B:60 B:63 55.0 0.367 -70.7 124.3 55.0 0.367 0.0 HOH
 2.827
 OD1
 O
6xzz 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 ASP A:60 A:63 66.0 0.44 S -80.1 123.9 66.0 0.44 0.0 CL
HOH
 7.860
5.087
 O
N
 CL
O
6y17 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 ASP A:71 A:63 59.0 0.393 S -71.6 123.1 59.0 0.393 0.0 HOH
 3.453
 N
 O
ASP B:71 B:63 55.0 0.367 -83.7 115.5 55.0 0.367 0.0 HOH
 3.866
 C
 O
6zbu 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 ASP A:71 A:63 61.0 0.407 S -66.8 130.7 61.0 0.407 0.0 SO4
 8.628
 N
 O2
ASP B:71 B:63 60.0 0.4 S -70.1 118.6 60.0 0.4 0.0 SO4
HOH
 9.107
2.477
 N
OD1
 O4
O
ASP E:71 E:63 67.0 0.447 -66.6 121.0 67.0 0.447 0.0 SO4
SO4
SO4
HOH
 6.881
8.880
8.690
7.306
 O
N
O
O
 O1
O3
O2
O
ASP F:71 F:63 59.0 0.393 S -77.7 125.8 59.0 0.393 0.0 SO4
 7.459
 O
 O2
ASP H:71 I:63 54.0 0.36 -68.4 130.3 54.0 0.36 0.0 SO4
SO4
SO4
SO4
HOH
 9.046
8.691
8.737
6.553
3.809
 O
N
N
O
OD1
 O4
O2
O2
O4
O
ASP I:71 J:63 55.0 0.367 S -75.1 123.1 55.0 0.367 0.0 SO4
 7.919
 O
 O2
5n1z 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 ASP A:58 A:63 67.0 0.447 S -79.7 119.6 67.0 0.447 0.0 HOH
 3.902
 CB
 O
5n20 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 ASP A:58 A:63 74.0 0.493 S -75.0 122.5 74.0 0.493 0.0 8GN
HOH
 9.519
2.792
 N
OD1
 O
O
5n21 1 P41182 97.54 5e-78 X-RAY
 2017-05-17 ASP A:57 A:63 74.0 0.493 S -74.6 121.0 74.0 0.493 0.0 8HN
HOH
 9.960
2.717
 N
OD1
 N4
O
ASP B:57 B:63 75.0 0.5 S -76.3 122.3 NA NA NA
6ew7 1 P41182 97.54 5e-78 X-RAY
 2018-10-24 ASP A:57 A:63 73.0 0.487 S -78.7 121.7 73.0 0.487 0.0 HOH
 2.719
 OD2
 O
ASP B:57 B:63 70.0 0.467 S -81.0 118.1 70.0 0.467 0.0 HOH
 3.752
 N
 O
4cp3 1 P41182 97.54 5e-78 X-RAY
 2014-03-19 ASP A:59 A:63 66.0 0.44 S -58.3 103.7 66.0 0.44 0.0 HOH
 7.733
 O
 O
ASP B:59 B:63 54.0 0.36 S -87.8 123.6 54.0 0.36 0.0 HOH
 8.566
 N
 O
6ew6 1 P41182 96.75 2e-77 X-RAY
 2018-10-24 ASP A:58 A:63 73.0 0.487 S -73.7 122.8 73.0 0.487 0.0 C0H
HOH
 9.861
5.407
 H
O
 H3
O
5n1x 1 P41182 97.5 2e-76 X-RAY
 2017-05-17 ASP A:56 A:63 72.0 0.48 S -72.0 118.8 72.0 0.48 0.0 HOH
 6.741
 OD2
 O
5n1x 2 P41182 96.69 5e-76 X-RAY
 2017-05-17 ASP B:57 B:63 74.0 0.493 S -67.1 117.0 NA NA NA
ASP C:57 C:63 73.0 0.487 S -72.6 118.9 NA NA NA
5n1x 3 P41182 97.44 2e-74 X-RAY
 2017-05-17 ASP D:56 D:63 73.0 0.487 S -77.9 118.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p41182-f1 1 P41182 100.0 0.0 ASP A:63 A:63 102.0 0.68 H -76.8 -32.2