Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 187451339 . G A CCDS3289.1:NM_001130845.1:c.143aCg>aTg_NP_001124317.1:p.48T>M Homo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6xmx 1 P41182 99.72 0.0 EM
 2020-11-25 THR A:88 A:48 103.0 0.736 H -63.6 -39.6 9.0 0.064 0.672 B:P41182:0.671
 U52
 4.763
 O
 CL1
THR B:88 B:48 101.0 0.721 H -63.7 -39.6 7.0 0.05 0.671 A:P41182:0.671
 U52
 4.765
 O
 CL1
THR C:88 C:48 101.0 0.721 H -63.6 -39.7 9.0 0.064 0.657 D:P41182:0.657
 U52
 4.760
 O
 CL1
THR D:88 D:48 102.0 0.729 H -63.6 -39.7 7.0 0.05 0.679 C:P41182:0.679
 U52
 4.767
 O
 CL1
THR E:88 E:48 101.0 0.721 H -63.7 -39.6 7.0 0.05 0.671 F:P41182:0.671
 U52
 4.763
 O
 CL1
THR F:88 F:48 101.0 0.721 H -63.6 -39.7 8.0 0.057 0.664 E:P41182:0.664
 U52
 4.766
 O
 CL1
THR G:88 G:48 101.0 0.721 H -63.6 -39.6 7.0 0.05 0.671 H:P41182:0.671
 U52
 4.768
 O
 CL1
THR H:88 H:48 102.0 0.729 H -63.7 -39.6 8.0 0.057 0.672 G:P41182:0.671
 U52
 4.761
 O
 CL1
5h7g 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 THR A:60 A:48 102.0 0.729 H -65.5 -35.1 6.0 0.043 0.686 B:P41182:0.686
 HOH
 4.731
 OG1
 O
THR B:60 B:48 99.0 0.707 H -62.0 -38.8 7.0 0.05 0.657 A:P41182:0.657
 HOH
 2.920
 OG1
 O
5h7h 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 THR A:60 A:48 101.0 0.721 H -61.8 -38.1 8.0 0.057 0.664 A:P41182:0.664
 EDO
HOH
 9.306
2.585
 O
OG1
 C1
O
5x4m 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:60 A:48 97.0 0.693 H -61.6 -40.3 97.0 0.693 0.0 HOH
 2.685
 OG1
 O
5x4n 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:60 A:48 99.0 0.707 H -63.3 -40.5 99.0 0.707 0.0 HOH
 2.705
 OG1
 O
5x4o 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:60 A:48 99.0 0.707 H -60.5 -40.1 99.0 0.707 0.0 HOH
 2.627
 OG1
 O
5x4p 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:60 A:48 94.0 0.671 H -59.8 -42.6 94.0 0.671 0.0 HOH
 2.600
 OG1
 O
5x4q 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:60 A:48 100.0 0.714 H -64.7 -38.9 100.0 0.714 0.0 HOH
 2.624
 OG1
 O
5x9o 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 THR A:60 A:48 101.0 0.721 H -59.6 -38.4 101.0 0.721 0.0 HOH
 2.648
 OG1
 O
5x9p 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 THR A:60 A:48 100.0 0.714 H -65.8 -37.3 100.0 0.714 0.0 HOH
 2.689
 OG1
 O
6toj 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 THR A:63 A:48 101.0 0.721 H -60.2 -40.1 7.0 0.05 0.671 A:P41182:0.671
 NQQ
HOH
 4.681
2.730
 O
OG1
 N4
O
6tol 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 THR A:63 A:48 101.0 0.721 H -59.0 -41.1 7.0 0.05 0.671 A:P41182:0.671
 NQW
HOH
 5.083
2.690
 O
OG1
 CL
O
6tom 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 THR A:63 A:48 101.0 0.721 H -61.7 -36.0 7.0 0.05 0.671 A:P41182:0.671
 NQZ
HOH
 5.013
2.694
 O
OG1
 CL
O
7okd 1 P41182 100.0 1e-85 X-RAY
 2021-12-08 THR A:63 A:48 102.0 0.729 H -58.2 -41.0 7.0 0.05 0.679 A:P41182:0.679
 VGW
HOH
 4.844
2.731
 O
OG1
 N6
O
6tof 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:47 A:48 101.0 0.721 H -61.6 -37.8 8.0 0.057 0.664 A:P41182:0.664
 NQE
HOH
 4.409
2.733
 O
OG1
 N4
O
6tog 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:47 A:48 99.0 0.707 H -63.9 -40.2 6.0 0.043 0.664 A:P41182:0.664
 NQH
HOH
 4.801
2.713
 O
OG1
 N1
O
6toh 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:47 A:48 99.0 0.707 H -59.6 -41.1 7.0 0.05 0.657 A:P41182:0.657
 NQK
HOH
 4.705
2.713
 O
OG1
 N
O
6toi 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:47 A:48 100.0 0.714 H -62.7 -40.6 7.0 0.05 0.664 A:P41182:0.664
 NQN
HOH
 4.670
2.660
 O
OG1
 N4
O
6tok 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:47 A:48 103.0 0.736 H -60.0 -40.3 9.0 0.064 0.672 A:P41182:0.671
 NQT
HOH
 5.110
2.808
 O
OG1
 CL
O
6ton 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:47 A:48 100.0 0.714 H -56.0 -48.7 7.0 0.05 0.664 A:P41182:0.664
 NR5
HOH
 5.146
3.052
 O
N
 CL
O
6too 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:47 A:48 101.0 0.721 H -61.1 -37.6 7.0 0.05 0.671 A:P41182:0.671
 NR8
EDO
HOH
 4.749
8.953
2.692
 O
CG2
OG1
 N1
O1
O
7oke 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 99.0 0.707 H -62.3 -37.5 7.0 0.05 0.657 A:P41182:0.657
 VHQ
HOH
 4.752
2.711
 O
OG1
 N3
O
7okf 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 100.0 0.714 H -62.6 -36.9 7.0 0.05 0.664 A:P41182:0.664
 VH5
HOH
 4.943
2.748
 O
OG1
 N5
O
7okg 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 101.0 0.721 H -64.6 -37.4 8.0 0.057 0.664 A:P41182:0.664
 VHB
HOH
 4.865
2.764
 O
OG1
 N4
O
7okh 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 101.0 0.721 H -62.4 -37.4 7.0 0.05 0.671 A:P41182:0.671
 VHK
HOH
 4.917
2.713
 O
OG1
 N4
O
7oki 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 101.0 0.721 H -62.2 -38.5 8.0 0.057 0.664 A:P41182:0.664
 VHZ
HOH
 4.912
2.729
 O
OG1
 N1
O
7okj 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 99.0 0.707 H -63.2 -37.2 7.0 0.05 0.657 A:P41182:0.657
 VHN
VHZ
HOH
 4.908
4.891
2.718
 O
O
OG1
 N1
N1
O
7okk 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 101.0 0.721 H -61.6 -38.7 7.0 0.05 0.671 A:P41182:0.671
 VH8
HOH
 4.876
2.618
 O
OG1
 N1
O
7okl 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 103.0 0.736 H -60.7 -39.7 9.0 0.064 0.672 A:P41182:0.671
 VJ5
HOH
 4.899
2.811
 O
OG1
 N4
O
7okm 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:47 A:48 103.0 0.736 H -60.1 -39.7 9.0 0.064 0.672 A:P41182:0.671
 VJ2
HOH
 4.833
2.782
 O
OG1
 N6
O
3e4u 1 P41182 100.0 2e-85 X-RAY
 2008-12-09 THR A:49 A:48 98.0 0.7 H -68.1 -36.8 4.0 0.029 0.671 B:P41182:0.671
 HOH
 2.570
 OG1
 O
THR B:49 B:48 101.0 0.721 H -40.0 -44.0 6.0 0.043 0.678 A:P41182:0.679
 HOH
 2.651
 OG1
 O
THR C:49 C:48 100.0 0.714 H -62.5 -41.8 NA NA NA
THR D:49 D:48 97.0 0.693 H -49.7 -41.7 NA NA NA
THR E:49 E:48 97.0 0.693 H -78.4 -36.9 NA NA NA
THR F:49 F:48 91.0 0.65 H -59.9 -47.9 NA NA NA
4u2m 1 Q13105,P41182 99.21 3e-83 X-RAY
 2014-12-10 THR A:175 A:171 6.0 0.043 H -63.8 -37.6 6.0 0.043 0.0 HOH
 2.978
 N
 O
THR B:175 B:171 11.0 0.079 H -62.2 -39.0 NA NA NA
THR C:175 C:171 8.0 0.057 H -63.5 -39.5 NA NA NA
THR D:175 D:171 7.0 0.05 H -62.3 -38.8 NA NA NA
6c3l 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 THR A:50 A:48 100.0 0.714 H -62.2 -40.3 100.0 0.714 0.0 EGP
HOH
 6.294
3.115
 O
N
 SAC
O
THR B:50 B:48 100.0 0.714 H -62.7 -39.8 NA NA NA
6c3n 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 THR A:50 A:48 97.0 0.693 H -57.5 -46.9 8.0 0.057 0.636 B:P41182:0.636
 EHY
HOH
 6.235
3.068
 O
OG1
 SAA
O
THR B:50 B:48 102.0 0.729 H -59.3 -42.4 8.0 0.057 0.672 A:P41182:0.671
 EHY
HOH
 6.421
2.978
 O
OG1
 SAA
O
6cq1 1 P41182 96.9 2e-82 X-RAY
 2019-03-20 THR A:50 A:48 100.0 0.714 H -59.1 -42.1 6.0 0.043 0.671 B:P41182:0.671
 F8J
HOH
 6.350
2.631
 O
OG1
 SAE
O
THR B:50 B:48 102.0 0.729 H -59.3 -44.2 6.0 0.043 0.686 A:P41182:0.686
 F8J
HOH
 6.303
2.612
 O
OG1
 SAE
O
6xwf 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 THR A:54 A:48 101.0 0.721 H -64.5 -36.1 6.0 0.043 0.678 A:P41182:0.679
 HOH
 2.601
 OG1
 O
6xxs 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 THR A:54 A:48 92.0 0.657 H -67.8 -42.4 6.0 0.043 0.614 B:P41182:0.614
THR B:54 B:48 104.0 0.743 H -63.0 -45.2 5.0 0.036 0.707 A:P41182:0.707
THR G:54 F:48 102.0 0.729 H -68.7 -39.4 4.0 0.029 0.7 E:P41182:0.7
5mw2 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 THR A:45 A:48 101.0 0.721 H -63.4 -39.4 8.0 0.057 0.664 A:P41182:0.664
 U52
HOH
 5.320
3.493
 O
N
 CL1
O
5mw6 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 THR A:45 A:48 100.0 0.714 H -59.9 -37.7 5.0 0.036 0.678 B:P41182:0.679
 RC0
HOH
 4.906
2.709
 O
OG1
 CL4
O
THR B:45 B:48 100.0 0.714 H -58.5 -45.6 6.0 0.043 0.671 A:P41182:0.671
 RC0
HOH
 4.828
2.730
 O
OG1
 CL4
O
5mwd 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 THR A:45 A:48 103.0 0.736 H -57.4 -43.9 7.0 0.05 0.686 A:P41182:0.686
 TJ3
HOH
 4.912
2.825
 O
OG1
 CL1
O
1r28 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 THR A:46 A:48 96.0 0.686 H -64.0 -36.7 6.0 0.043 0.643 B:P41182:0.643
 HOH
 2.671
 OG1
 O
THR B:46 B:48 101.0 0.721 H -61.9 -38.7 6.0 0.043 0.678 A:P41182:0.679
 HOH
 2.699
 OG1
 O
1r29 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 THR A:46 A:48 99.0 0.707 H -62.4 -40.1 6.0 0.043 0.664 A:P41182:0.664
 HOH
 2.787
 OG1
 O
1r2b 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 THR A:46 A:48 100.0 0.714 H -53.5 -41.7 5.0 0.036 0.678 B:P41182:0.679
 HOH
 2.597
 OG1
 O
THR B:46 B:48 98.0 0.7 H -59.7 -38.0 7.0 0.05 0.65 A:P41182:0.65
 HOH
 2.754
 OG1
 O
3bim 1 P41182 97.6 2e-80 X-RAY
 2008-01-08 THR A:46 A:48 97.0 0.693 H -62.8 -35.6 NA NA NA
THR C:46 B:48 97.0 0.693 H -71.8 -28.3 NA NA NA
THR E:46 C:48 101.0 0.721 H -61.0 -42.3 8.0 0.057 0.664 G:P41182:0.664
 HOH
 5.159
 OG1
 O
THR G:46 D:48 101.0 0.721 H -59.2 -36.7 6.0 0.043 0.678 E:P41182:0.679
 HOH
 2.999
 N
 O
THR I:46 E:48 96.0 0.686 H -58.8 -35.2 NA NA NA
THR K:46 F:48 102.0 0.729 H -69.0 -33.6 NA NA NA
THR M:46 G:48 101.0 0.721 H -71.6 -29.1 NA NA NA
THR O:46 H:48 98.0 0.7 H -69.4 -32.7 NA NA NA
3lbz 1 P41182 97.6 2e-80 X-RAY
 2010-04-28 THR A:46 A:48 99.0 0.707 H -63.8 -33.3 6.0 0.043 0.664 B:P41182:0.664
 Z89
HOH
 6.200
5.953
 O
OG1
 CAG
O
THR B:46 B:48 102.0 0.729 H -65.6 -34.5 8.0 0.057 0.672 A:P41182:0.671
 Z89
HOH
 6.429
4.125
 O
CG2
 CAG
O
7bde 1 P41182 97.6 3e-80 X-RAY
 2021-07-28 THR A:46 A:48 101.0 0.721 H -58.3 -39.2 4.0 0.029 0.692 A:P41182:0.693
 TEQ
HOH
 4.747
3.196
 O
OG1
 F
O
6ew8 1 P41182 97.58 1e-79 X-RAY
 2018-10-24 THR A:43 A:48 105.0 0.75 H -58.1 -42.8 7.0 0.05 0.7 A:P41182:0.7
 C0Q
HOH
 5.177
2.727
 O
OG1
 CL
O
6tbt 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 THR A:45 A:48 106.0 0.757 H -60.1 -42.9 9.0 0.064 0.693 B:P41182:0.693
 CL
GOL
HOH
 8.363
2.972
2.836
 CG2
OG1
OG1
 CL
O2
O
THR B:45 B:48 105.0 0.75 H -59.6 -43.5 10.0 0.071 0.679 A:P41182:0.679
 GOL
HOH
 2.871
2.781
 OG1
OG1
 O2
O
6tcj 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 THR A:45 A:48 98.0 0.7 H -59.5 -40.4 6.0 0.043 0.657 B:P41182:0.657
 HOH
 2.555
 OG1
 O
THR B:45 B:48 99.0 0.707 H -62.8 -35.8 7.0 0.05 0.657 A:P41182:0.657
 HOH
 2.590
 OG1
 O
6xxs 3 P41182 97.58 1e-79 X-RAY
 2020-12-02 THR E:45 E:48 100.0 0.714 H -67.6 -41.1 4.0 0.029 0.685 G:P41182:0.686
6xyx 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 THR A:45 A:48 100.0 0.714 H -59.8 -41.5 7.0 0.05 0.664 B:P41182:0.664
 NA
HOH
 2.790
2.672
 OG1
OG1
 NA
O
THR B:45 B:48 102.0 0.729 H -59.2 -43.3 8.0 0.057 0.672 A:P41182:0.671
 NA
HOH
 2.793
2.794
 OG1
OG1
 NA
O
6xzz 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 THR A:45 A:48 100.0 0.714 H -65.8 -36.3 7.0 0.05 0.664 A:P41182:0.664
 CL
NA
HOH
 8.714
9.516
2.701
 CG2
O
OG1
 CL
NA
O
6y17 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 THR A:56 A:48 98.0 0.7 H -62.5 -38.0 6.0 0.043 0.657 B:O75376+P41182:0.657
 HOH
 2.704
 OG1
 O
THR B:56 B:48 96.0 0.686 H -65.7 -39.2 6.0 0.043 0.643 A:O75376+P41182:0.643
 HOH
 2.664
 OG1
 O
6zbu 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 THR A:56 A:48 103.0 0.736 H -61.8 -44.1 9.0 0.064 0.672 B:O75376+P41182:0.671
 HOH
 4.139
 CG2
 O
THR B:56 B:48 106.0 0.757 H -61.8 -42.6 9.0 0.064 0.693 A:O75376+P41182:0.693
 HOH
 5.931
 OG1
 O
THR E:56 E:48 101.0 0.721 H -63.4 -39.7 8.0 0.057 0.664 F:O75376+P41182:0.664
 SO4
HOH
 8.268
3.272
 CG2
N
 O4
O
THR F:56 F:48 101.0 0.721 H -61.2 -41.9 7.0 0.05 0.671 E:O75376+P41182:0.671
 SO4
HOH
 8.747
5.152
 CG2
OG1
 O2
O
THR H:56 I:48 103.0 0.736 H -61.9 -40.7 9.0 0.064 0.672 I:O75376+P41182:0.671
 SO4
HOH
 8.286
3.147
 CG2
N
 O1
O
THR I:56 J:48 99.0 0.707 H -62.5 -41.3 8.0 0.057 0.65 H:O75376+P41182:0.65
 SO4
HOH
 8.447
5.513
 CG2
OG1
 O3
O
5n1z 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 THR A:43 A:48 103.0 0.736 H -62.1 -38.7 7.0 0.05 0.686 A:P41182:0.686
 8GQ
HOH
 5.321
2.705
 O
OG1
 N4
O
5n20 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 THR A:43 A:48 103.0 0.736 H -62.9 -39.0 7.0 0.05 0.686 A:P41182:0.686
 8GN
HOH
 6.231
3.088
 O
N
 N6
O
5n21 1 P41182 97.54 5e-78 X-RAY
 2017-05-17 THR A:42 A:48 104.0 0.743 H -59.5 -43.0 104.0 0.743 0.0 8HN
HOH
 5.614
2.782
 O
OG1
 N3
O
THR B:42 B:48 102.0 0.729 H -58.8 -41.5 NA NA NA
6ew7 1 P41182 97.54 5e-78 X-RAY
 2018-10-24 THR A:42 A:48 101.0 0.721 H -56.8 -46.4 6.0 0.043 0.678 B:P41182:0.679
 C1W
HOH
 4.969
2.728
 O
OG1
 CL1
O
THR B:42 B:48 101.0 0.721 H -57.5 -42.6 7.0 0.05 0.671 A:P41182:0.671
 C1W
HOH
 5.001
2.712
 O
OG1
 CL1
O
4cp3 1 P41182 97.54 5e-78 X-RAY
 2014-03-19 THR A:44 A:48 95.0 0.679 H -60.3 -38.0 4.0 0.029 0.65 B:P41182:0.65
 HOH
 2.959
 OG1
 O
THR B:44 B:48 98.0 0.7 H -57.4 -40.5 6.0 0.043 0.657 A:P41182:0.657
 RBT
HOH
 6.906
5.017
 O
CG2
 C14
O
6ew6 1 P41182 96.75 2e-77 X-RAY
 2018-10-24 THR A:43 A:48 102.0 0.729 H -58.7 -44.9 102.0 0.729 0.0 C0H
HOH
 6.417
2.092
 O
H
 N1
O
5n1x 1 P41182 97.5 2e-76 X-RAY
 2017-05-17 THR A:41 A:48 103.0 0.736 H -58.2 -44.0 103.0 0.736 0.0 HOH
 3.185
 N
 O
5n1x 2 P41182 96.69 5e-76 X-RAY
 2017-05-17 THR B:42 B:48 101.0 0.721 H -57.8 -42.9 NA NA NA
THR C:42 C:48 104.0 0.743 H -56.4 -44.9 NA NA NA
5n1x 3 P41182 97.44 2e-74 X-RAY
 2017-05-17 THR D:41 D:48 103.0 0.736 H -57.8 -43.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p41182-f1 1 P41182 100.0 0.0 THR A:48 A:48 110.0 0.786 H -65.5 -35.5