Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 187451406 . G A CCDS3289.1:NM_001130845.1:c.76Cgg>Tgg_NP_001124317.1:p.26R>W Homo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6xmx 1 P41182 99.72 0.0 EM
 2020-11-25 ARG A:66 A:26 48.0 0.213 H -63.5 -40.6 17.0 0.076 0.137 D:P41182:0.138
 U52
U52
 5.996
8.638
 H
HH12
 H8
H29
ARG B:66 B:26 49.0 0.218 H -63.4 -40.7 17.0 0.076 0.142 E:P41182:0.142
 U52
U52
 5.822
8.630
 H
HH12
 H8
H29
ARG C:66 C:26 48.0 0.213 H -63.5 -40.6 48.0 0.213 0.0 U52
 6.279
 H
 H8
ARG D:66 D:26 48.0 0.213 H -63.5 -40.6 16.0 0.071 0.142 A:P41182:0.142
 U52
U52
 9.261
5.805
 HH12
H
 H29
H8
ARG E:66 E:26 49.0 0.218 H -63.5 -40.6 18.0 0.08 0.138 B:P41182:0.138
 U52
U52
 8.536
5.869
 HH12
H
 H29
H8
ARG F:66 F:26 49.0 0.218 H -63.5 -40.6 18.0 0.08 0.138 G:P41182:0.138
 U52
U52
 6.133
8.580
 H
HH12
 H8
H29
ARG G:66 G:26 48.0 0.213 H -63.5 -40.6 18.0 0.08 0.133 F:P41182:0.133
 U52
U52
 8.619
5.710
 HH12
H
 H29
H8
ARG H:66 H:26 47.0 0.209 H -63.4 -40.7 47.0 0.209 0.0 U52
 6.146
 H
 H8
5h7g 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 ARG A:38 A:26 44.0 0.196 H -65.3 -43.2 44.0 0.196 0.0 HOH
 2.809
 O
 O
ARG B:38 B:26 46.0 0.204 H -61.0 -49.2 46.0 0.204 0.0 HOH
 2.645
 NH1
 O
5h7h 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 ARG A:38 A:26 44.0 0.196 H -56.4 -50.9 44.0 0.196 0.0 HOH
 2.780
 O
 O
5x4m 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ARG A:38 A:26 41.0 0.182 H -60.0 -45.2 41.0 0.182 0.0 7ZF
HOH
 6.467
2.624
 N
O
 N13
O
5x4n 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ARG A:38 A:26 42.0 0.187 H -61.2 -48.0 42.0 0.187 0.0 7ZL
HOH
 7.516
3.043
 N
NH1
 C6
O
5x4o 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ARG A:38 A:26 42.0 0.187 H -60.8 -48.4 42.0 0.187 0.0 YAM
HOH
 6.271
2.774
 N
NH1
 F29
O
5x4p 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ARG A:38 A:26 45.0 0.2 H -60.2 -50.2 45.0 0.2 0.0 7ZO
HOH
 7.617
3.577
 N
NH2
 C4
O
5x4q 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 ARG A:38 A:26 44.0 0.196 H -62.6 -47.8 44.0 0.196 0.0 7Z6
HOH
 7.500
2.975
 N
NH1
 C8
O
5x9o 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 ARG A:38 A:26 41.0 0.182 H -61.2 -44.6 41.0 0.182 0.0 80R
HOH
 6.717
2.655
 N
O
 O20
O
5x9p 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 ARG A:38 A:26 41.0 0.182 H -62.4 -46.3 41.0 0.182 0.0 80L
HOH
 6.692
2.886
 N
NH1
 O25
O
6toj 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 ARG A:41 A:26 41.0 0.182 H -58.6 -48.8 41.0 0.182 0.0 EDO
NQQ
HOH
 9.417
6.393
2.946
 NH1
N
NH1
 C2
CL
O
6tol 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 ARG A:41 A:26 42.0 0.187 H -58.9 -46.2 42.0 0.187 0.0 EDO
DMS
NQW
HOH
 5.724
8.893
7.550
2.691
 NH2
NH1
N
O
 O1
C1
C22
O
6tom 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 ARG A:41 A:26 43.0 0.191 H -59.8 -49.5 43.0 0.191 0.0 NQZ
HOH
 7.586
2.641
 N
O
 C23
O
7okd 1 P41182 100.0 1e-85 X-RAY
 2021-12-08 ARG A:41 A:26 44.0 0.196 H -58.4 -48.2 44.0 0.196 0.0 DMS
DMS
VGW
HOH
 8.743
8.625
6.855
3.004
 NH1
NH2
N
NH1
 C2
O
CL
O
6tof 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ARG A:25 A:26 44.0 0.196 H -60.1 -45.6 44.0 0.196 0.0 EDO
NQE
HOH
 2.734
7.543
2.942
 O
N
NH1
 O2
C12
O
6tog 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ARG A:25 A:26 43.0 0.191 H -63.3 -45.6 43.0 0.191 0.0 DMS
NQH
HOH
 6.714
7.116
2.791
 C
N
NH1
 C2
CL
O
6toh 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ARG A:25 A:26 44.0 0.196 H -60.5 -45.7 44.0 0.196 0.0 EDO
NQK
HOH
 9.615
6.509
2.684
 N
N
O
 O2
CL
O
6toi 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ARG A:25 A:26 44.0 0.196 H -59.6 -45.7 44.0 0.196 0.0 DMS
NQN
HOH
 9.831
6.319
2.705
 NH1
N
O
 C2
CL
O
6tok 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ARG A:25 A:26 46.0 0.204 H -61.1 -47.0 46.0 0.204 0.0 EDO
EDO
EDO
EDO
EDO
DMS
DMS
NQT
HOH
 7.580
7.314
2.724
9.799
7.459
9.474
6.549
7.678
3.090
 O
NH1
O
N
C
NH1
NH2
N
NH1
 O1
O1
O2
O2
C2
O
C1
C21
O
6ton 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ARG A:25 A:26 43.0 0.191 H -59.0 -51.4 43.0 0.191 0.0 NR5
HOH
 7.912
2.831
 N
NH1
 C12
O
6too 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 ARG A:25 A:26 44.0 0.196 H -60.2 -46.6 44.0 0.196 0.0 EDO
NR8
HOH
 8.008
6.546
2.712
 O
N
O
 O2
CL
O
7oke 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 46.0 0.204 H -60.7 -48.3 46.0 0.204 0.0 EDO
EDO
VHQ
HOH
 9.774
2.966
6.615
2.673
 NH1
NH1
N
O
 C2
O1
CL
O
7okf 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 43.0 0.191 H -58.8 -48.5 43.0 0.191 0.0 DMS
DMS
VH5
HOH
 9.719
6.646
7.025
2.702
 NH1
NH2
N
O
 O
C1
CL
O
7okg 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 43.0 0.191 H -61.8 -45.1 43.0 0.191 0.0 VHB
HOH
 6.889
2.608
 N
O
 CL
O
7okh 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 45.0 0.2 H -59.3 -48.0 45.0 0.2 0.0 VHK
HOH
 6.821
2.683
 N
O
 CL
O
7oki 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 44.0 0.196 H -59.1 -47.8 44.0 0.196 0.0 DMS
VHZ
HOH
 9.913
6.791
2.691
 NH1
N
O
 O
CL
O
7okj 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 44.0 0.196 H -59.6 -46.4 44.0 0.196 0.0 EDO
VHN
VHZ
HOH
 7.360
6.850
6.814
2.614
 O
N
N
O
 O1
CL
CL
O
7okk 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 46.0 0.204 H -60.9 -45.7 46.0 0.204 0.0 EDO
VH8
HOH
 9.805
6.666
2.668
 NH1
N
O
 C2
CL
O
7okl 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 46.0 0.204 H -59.8 -46.7 46.0 0.204 0.0 EDO
VJ5
HOH
 9.257
6.905
2.713
 NH1
N
O
 O2
CL
O
7okm 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 ARG A:25 A:26 46.0 0.204 H -60.0 -45.9 46.0 0.204 0.0 DMS
VJ2
HOH
 9.559
6.796
2.702
 NH1
N
O
 O
CL
O
3e4u 1 P41182 100.0 2e-85 X-RAY
 2008-12-09 ARG A:27 A:26 47.0 0.209 H -67.5 -51.1 47.0 0.209 0.0 HOH
 2.618
 O
 O
ARG B:27 B:26 43.0 0.191 H -59.0 -47.5 43.0 0.191 0.0 HOH
 3.008
 NH1
 O
ARG C:27 C:26 43.0 0.191 H -63.8 -52.8 NA NA NA
ARG D:27 D:26 39.0 0.173 H -56.2 -49.9 NA NA NA
ARG E:27 E:26 54.0 0.24 H -58.2 -39.6 NA NA NA
ARG F:27 F:26 50.0 0.222 H -58.5 -50.5 NA NA NA
4u2m 1 Q13105,P41182 99.21 3e-83 X-RAY
 2014-12-10 ARG A:153 A:149 43.0 0.191 H -61.2 -45.6 43.0 0.191 0.0 HOH
 5.986
 O
 O
ARG B:153 B:149 44.0 0.196 H -62.7 -46.1 NA NA NA
ARG C:153 C:149 43.0 0.191 H -61.4 -44.3 NA NA NA
ARG D:153 D:149 47.0 0.209 H -63.5 -45.2 NA NA NA
6c3l 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 ARG A:28 A:26 39.0 0.173 H -62.2 -42.6 39.0 0.173 0.0 HOH
 2.667
 NH1
 O
ARG B:28 B:26 40.0 0.178 H -61.2 -42.7 NA NA NA
6c3n 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 ARG A:28 A:26 41.0 0.182 H -69.3 -40.2 41.0 0.182 0.0 EHY
HOH
 8.073
3.765
 N
NH1
 SAA
O
ARG B:28 B:26 44.0 0.196 H -65.3 -36.9 44.0 0.196 0.0 EHY
HOH
 7.826
2.875
 N
NH1
 SAA
O
6cq1 1 P41182 96.9 2e-82 X-RAY
 2019-03-20 ARG A:28 A:26 43.0 0.191 H -61.3 -40.4 43.0 0.191 0.0 F8J
HOH
 7.938
2.668
 N
NH1
 SAE
O
ARG B:28 B:26 40.0 0.178 H -62.3 -42.4 40.0 0.178 0.0 F8J
HOH
 7.923
2.861
 N
NH1
 SAE
O
6xwf 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 ARG A:32 A:26 44.0 0.196 H -62.7 -44.6 44.0 0.196 0.0 HOH
 2.708
 O
 O
6xxs 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 ARG A:32 A:26 71.0 0.316 H -62.6 -47.6 8.0 0.036 0.28 G:P41182:0.28
ARG B:32 B:26 36.0 0.16 H -63.3 -49.7 36.0 0.16 0.0
ARG G:32 F:26 43.0 0.191 H -67.1 -47.7 43.0 0.191 0.0
5mw2 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 ARG A:23 A:26 45.0 0.2 H -64.3 -41.9 45.0 0.2 0.0 U52
HOH
 7.864
4.289
 N
NH2
 C26
O
5mw6 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 ARG A:23 A:26 40.0 0.178 H -61.8 -46.2 40.0 0.178 0.0 RC0
HOH
 7.268
2.684
 N
O
 C12
O
ARG B:23 B:26 45.0 0.2 H -60.0 -49.3 45.0 0.2 0.0 RC0
HOH
 7.465
2.675
 N
O
 C12
O
5mwd 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 ARG A:23 A:26 39.0 0.173 H -61.5 -44.3 39.0 0.173 0.0 TJ3
HOH
 7.609
2.702
 N
O
 C3
O
1r28 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 ARG A:24 A:26 45.0 0.2 H -66.3 -47.9 45.0 0.2 0.0 HOH
 2.814
 NH1
 O
ARG B:24 B:26 42.0 0.187 H -61.9 -54.4 42.0 0.187 0.0 HOH
 3.826
 NH1
 O
1r29 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 ARG A:24 A:26 38.0 0.169 H -60.3 -42.8 38.0 0.169 0.0 HOH
 2.756
 O
 O
1r2b 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 ARG A:24 A:26 38.0 0.169 H -65.6 -47.8 38.0 0.169 0.0 HOH
 2.738
 NH1
 O
ARG B:24 B:26 38.0 0.169 H -52.6 -57.5 38.0 0.169 0.0 HOH
 3.102
 NH2
 O
3bim 1 P41182 97.6 2e-80 X-RAY
 2008-01-08 ARG A:24 A:26 38.0 0.169 H -65.0 -48.6 NA NA NA
ARG C:24 B:26 45.0 0.2 H -64.8 -45.1 NA NA NA
ARG E:24 C:26 35.0 0.156 H -61.2 -52.8 35.0 0.156 0.0 HOH
 9.118
 O
 O
ARG G:24 D:26 39.0 0.173 H -64.0 -44.7 39.0 0.173 0.0 HOH
 3.001
 NH1
 O
ARG I:24 E:26 43.0 0.191 H -63.8 -37.0 NA NA NA
ARG K:24 F:26 46.0 0.204 H -64.4 -49.6 NA NA NA
ARG M:24 G:26 42.0 0.187 H -65.5 -52.3 NA NA NA
ARG O:24 H:26 45.0 0.2 H -55.3 -40.0 NA NA NA
3lbz 1 P41182 97.6 2e-80 X-RAY
 2010-04-28 ARG A:24 A:26 43.0 0.191 H -59.6 -46.8 43.0 0.191 0.0 Z89
HOH
 6.565
3.439
 N
NH1
 BRAE
O
ARG B:24 B:26 44.0 0.196 H -62.5 -42.7 44.0 0.196 0.0 Z89
HOH
 6.686
3.049
 N
NH1
 BRAE
O
7bde 1 P41182 97.6 3e-80 X-RAY
 2021-07-28 ARG A:24 A:26 41.0 0.182 H -66.1 -47.7 41.0 0.182 0.0 TEQ
HOH
 7.093
2.823
 N
NH1
 C11
O
6ew8 1 P41182 97.58 1e-79 X-RAY
 2018-10-24 ARG A:21 A:26 42.0 0.187 H -58.4 -41.5 42.0 0.187 0.0 C0Q
HOH
 6.914
2.684
 N
O
 H19
O
6tbt 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 ARG A:23 A:26 36.0 0.16 H -62.2 -45.9 36.0 0.16 0.0 GOL
HOH
 9.167
2.832
 N
NH1
 O3
O
ARG B:23 B:26 28.0 0.124 H -59.6 -48.3 28.0 0.124 0.0 CL
GOL
HOH
 9.718
9.656
2.978
 N
N
NH1
 CL
C1
O
6tcj 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 ARG A:23 A:26 43.0 0.191 H -61.3 -49.0 43.0 0.191 0.0 HOH
 2.787
 NH1
 O
ARG B:23 B:26 44.0 0.196 H -63.1 -44.3 44.0 0.196 0.0 HOH
 2.798
 NH1
 O
6xxs 3 P41182 97.58 1e-79 X-RAY
 2020-12-02 ARG E:23 E:26 44.0 0.196 H -60.8 -40.7 44.0 0.196 0.0
6xyx 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 ARG A:23 A:26 39.0 0.173 H -58.9 -47.1 39.0 0.173 0.0 HOH
 2.663
 O
 O
ARG B:23 B:26 40.0 0.178 H -59.9 -49.3 40.0 0.178 0.0 NA
EDO
NA
HOH
 9.601
7.675
9.668
2.662
 N
NH2
O
O
 NA
C2
NA
O
6xzz 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 ARG A:23 A:26 40.0 0.178 H -63.0 -43.9 40.0 0.178 0.0 NA
NA
CL
HOH
 6.670
7.107
9.456
2.840
 N
NH2
N
NH1
 NA
NA
CL
O
6y17 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 ARG A:34 A:26 29.0 0.129 H -63.2 -47.4 29.0 0.129 0.0 NA
HOH
 8.048
3.005
 NH1
NH1
 NA
O
ARG B:34 B:26 43.0 0.191 H -59.6 -41.9 43.0 0.191 0.0 HOH
 2.700
 O
 O
6zbu 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 ARG A:34 A:26 31.0 0.138 H -58.2 -42.8 31.0 0.138 0.0 SO4
SO4
HOH
 9.999
7.698
2.829
 NH2
NH2
NH2
 O2
O2
O
ARG B:34 B:26 32.0 0.142 H -57.9 -49.3 32.0 0.142 0.0 SO4
HOH
 9.028
3.577
 NH2
CG
 O4
O
ARG E:34 E:26 40.0 0.178 H -59.2 -46.0 40.0 0.178 0.0 SO4
SO4
SO4
HOH
 5.115
9.150
9.111
2.551
 NH1
NH2
O
NH1
 O2
O3
O3
O
ARG F:34 F:26 28.0 0.124 H -57.5 -49.9 28.0 0.124 0.0 SO4
HOH
 9.195
2.674
 O
NH1
 O2
O
ARG H:34 I:26 43.0 0.191 H -59.1 -45.3 43.0 0.191 0.0 SO4
SO4
GOL
SO4
HOH
 4.515
8.924
7.119
9.061
2.839
 NH1
NH2
O
O
NH1
 O4
O2
O3
O4
O
ARG I:34 J:26 31.0 0.138 H -58.1 -49.9 31.0 0.138 0.0 SO4
SO4
 8.324
9.474
 O
O
 O4
O3
5n1z 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 ARG A:21 A:26 42.0 0.187 H -62.1 -43.9 42.0 0.187 0.0 8GQ
HOH
 5.559
2.876
 N
NH1
 N5
O
5n20 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 ARG A:21 A:26 39.0 0.173 H -60.8 -42.4 39.0 0.173 0.0 8GN
HOH
 6.938
2.726
 N
O
 N7
O
5n21 1 P41182 97.54 5e-78 X-RAY
 2017-05-17 ARG A:20 A:26 40.0 0.178 H -58.2 -47.0 40.0 0.178 0.0 HOH
 2.763
 O
 O
ARG B:20 B:26 42.0 0.187 H -62.3 -45.9 NA NA NA
6ew7 1 P41182 97.54 5e-78 X-RAY
 2018-10-24 ARG A:20 A:26 39.0 0.173 H -57.6 -47.2 39.0 0.173 0.0 C1W
HOH
 6.444
2.786
 N
O
 H5
O
ARG B:20 B:26 43.0 0.191 H -61.4 -43.9 43.0 0.191 0.0 C1W
HOH
 6.470
2.677
 N
O
 H5
O
4cp3 1 P41182 97.54 5e-78 X-RAY
 2014-03-19 ARG A:22 A:26 44.0 0.196 H -60.7 -40.3 44.0 0.196 0.0 RBT
HOH
 7.016
2.871
 N
NH1
 O2
O
ARG B:22 B:26 40.0 0.178 H -63.9 -48.8 40.0 0.178 0.0 HOH
 6.145
 NH1
 O
6ew6 1 P41182 96.75 2e-77 X-RAY
 2018-10-24 ARG A:21 A:26 40.0 0.178 H -61.3 -40.2 40.0 0.178 0.0 HOH
 1.845
 HH12
 O
5n1x 1 P41182 97.5 2e-76 X-RAY
 2017-05-17 ARG A:19 A:26 47.0 0.209 H -63.2 -45.7 47.0 0.209 0.0 HOH
 2.737
 O
 O
5n1x 2 P41182 96.69 5e-76 X-RAY
 2017-05-17 ARG B:20 B:26 46.0 0.204 H -62.4 -47.2 NA NA NA
ARG C:20 C:26 44.0 0.196 H -63.5 -45.7 NA NA NA
5n1x 3 P41182 97.44 2e-74 X-RAY
 2017-05-17 ARG D:19 D:26 47.0 0.209 H -62.2 -48.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p41182-f1 1 P41182 100.0 0.0 ARG A:26 A:26 228.0 1.0 -63.6 13.6