Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 187451448 . T A CCDS3289.1:NM_001130845.1:c.34Acc>Tcc_NP_001124317.1:p.12T>S Homo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6xmx 1 P41182 99.72 0.0 EM
 2020-11-25 THR A:52 A:12 119.0 0.85 T -63.2 -36.9 119.0 0.85 0.0 U52
 7.411
 N
 H13
THR B:52 B:12 123.0 0.879 T -63.3 -36.9 123.0 0.879 0.0 U52
 8.013
 N
 H13
THR C:52 C:12 124.0 0.886 T -63.3 -36.9 124.0 0.886 0.0 U52
 7.849
 N
 H13
THR D:52 D:12 122.0 0.871 T -63.2 -36.9 122.0 0.871 0.0 U52
 8.488
 N
 H13
THR E:52 E:12 120.0 0.857 T -63.3 -36.9 120.0 0.857 0.0 U52
 8.377
 N
 H13
THR F:52 F:12 119.0 0.85 T -63.3 -36.9 119.0 0.85 0.0 U52
 7.537
 N
 H13
THR G:52 G:12 120.0 0.857 T -63.4 -36.8 120.0 0.857 0.0 U52
 8.194
 N
 H13
THR H:52 H:12 121.0 0.864 T -63.3 -36.9 121.0 0.864 0.0 U52
 7.841
 N
 H13
5h7g 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 THR A:24 A:12 133.0 0.95 T -71.9 -19.8 80.0 0.571 0.379 C:None:0.379
 HOH
 2.889
 O
 O
THR B:24 B:12 135.0 0.964 T -68.9 -23.4 79.0 0.564 0.4 D:None:0.4
 HOH
 2.875
 O
 O
5h7h 1 P41182 100.0 1e-85 X-RAY
 2016-12-07 THR A:24 A:12 72.0 0.514 T -53.8 -45.2 72.0 0.514 0.0 EDO
HOH
 8.411
2.861
 C
O
 O2
O
5x4m 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:24 A:12 60.0 0.429 T -56.8 -42.5 60.0 0.429 0.0 HOH
 2.692
 OG1
 O
5x4n 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:24 A:12 61.0 0.436 T -55.8 -44.6 61.0 0.436 0.0 EDO
HOH
 8.609
2.830
 C
O
 O2
O
5x4o 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:24 A:12 66.0 0.471 T -60.1 -41.9 66.0 0.471 0.0 HOH
 2.802
 O
 O
5x4p 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:24 A:12 59.0 0.421 T -61.6 -43.0 59.0 0.421 0.0 HOH
 2.763
 O
 O
5x4q 1 P41182 100.0 1e-85 X-RAY
 2017-05-24 THR A:24 A:12 63.0 0.45 T -58.8 -42.3 63.0 0.45 0.0 EDO
HOH
 8.560
2.869
 N
O
 O2
O
5x9o 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 THR A:24 A:12 60.0 0.429 T -53.2 -45.4 60.0 0.429 0.0 EDO
HOH
 7.796
2.637
 N
OG1
 O1
O
5x9p 1 P41182 100.0 1e-85 X-RAY
 2017-08-16 THR A:24 A:12 47.0 0.336 T -53.5 -43.9 47.0 0.336 0.0 HOH
 2.851
 O
 O
6toj 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 THR A:27 A:12 85.0 0.607 T -48.9 -47.0 85.0 0.607 0.0 EDO
NQQ
HOH
 9.381
9.564
2.662
 OG1
C
OG1
 O1
C6
O
6tol 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 THR A:27 A:12 90.0 0.643 T -53.9 -49.5 90.0 0.643 0.0 EDO
EDO
NQW
EDO
HOH
 9.417
3.939
9.587
6.057
2.675
 OG1
O
C
O
OG1
 O1
O1
C20
O1
O
6tom 1 P41182 100.0 1e-85 X-RAY
 2020-04-22 THR A:27 A:12 64.0 0.457 T -56.2 -47.9 64.0 0.457 0.0 EDO
NQZ
HOH
 9.364
9.095
2.706
 OG1
C
OG1
 C1
C21
O
7okd 1 P41182 100.0 1e-85 X-RAY
 2021-12-08 THR A:27 A:12 89.0 0.636 T -50.8 -48.6 89.0 0.636 0.0 EDO
VGW
HOH
 9.342
8.627
2.721
 OG1
C
OG1
 O1
C15
O
6tof 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:11 A:12 113.0 0.807 T -49.1 -46.4 78.0 0.557 0.25 B:None:0.243
A:P41182:0.007
 HOH
 2.778
 O
 O
6tog 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:11 A:12 111.0 0.793 T -49.6 -46.9 80.0 0.571 0.222 B:None:0.221
 HOH
 2.663
 O
 O
6toh 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:11 A:12 126.0 0.9 T -49.9 -48.1 94.0 0.671 0.229 B:None:0.221
A:P41182:0.007
 HOH
 2.749
 OG1
 O
6toi 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:11 A:12 127.0 0.907 T -51.6 -47.5 96.0 0.686 0.221 B:None:0.214
A:P41182:0.007
 EDO
NQN
HOH
 8.893
9.657
2.957
 OG1
C
O
 C2
O1
O
6tok 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:11 A:12 128.0 0.914 T -52.1 -46.5 95.0 0.679 0.235 B:None:0.214
A:P41182:0.021
 NQT
HOH
 9.737
2.834
 C
O
 C13
O
6ton 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:11 A:12 128.0 0.914 T -47.8 -44.2 126.0 0.9 0.014 A:P41182:0.014
 NR5
HOH
 9.837
2.757
 C
OG1
 C5
O
6too 1 P41182 100.0 2e-85 X-RAY
 2020-04-22 THR A:11 A:12 122.0 0.871 T -51.5 -46.6 92.0 0.657 0.214 B:None:0.207
A:P41182:0.007
 EDO
NR8
HOH
 8.483
9.707
2.722
 OG1
C
O
 O2
C16
O
7oke 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 125.0 0.893 T -50.3 -48.0 94.0 0.671 0.222 B:None:0.214
 EDO
HOH
 8.664
2.785
 OG1
O
 C2
O
7okf 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 126.0 0.9 T -47.7 -50.2 95.0 0.679 0.221 B:None:0.214
A:P41182:0.007
 CL
HOH
 9.899
2.776
 N
O
 CL
O
7okg 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 126.0 0.9 T -51.8 -46.4 94.0 0.671 0.229 B:None:0.221
A:P41182:0.007
 VHB
HOH
 9.468
2.796
 C
O
 C
O
7okh 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 125.0 0.893 T -47.9 -47.3 94.0 0.671 0.222 B:None:0.221
A:P41182:0.007
 EDO
VHK
CL
HOH
 8.461
9.631
9.984
2.865
 OG1
C
N
O
 C2
C10
CL
O
7oki 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 126.0 0.9 T -49.7 -49.1 96.0 0.686 0.214 B:None:0.214
 EDO
VHZ
HOH
 8.248
8.512
2.787
 OG1
C
O
 C2
O1
O
7okj 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 126.0 0.9 T -48.8 -47.4 95.0 0.679 0.221 B:None:0.221
 VHZ
CL
HOH
 8.163
9.969
2.766
 C
N
O
 O1
CL
O
7okk 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 126.0 0.9 T -50.0 -45.6 95.0 0.679 0.221 B:None:0.221
A:P41182:0.007
 HOH
 2.644
 O
 O
7okl 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 129.0 0.921 T -46.3 -51.7 98.0 0.7 0.221 B:None:0.214
A:P41182:0.007
 VJ5
HOH
 8.676
2.851
 C
OG1
 C19
O
7okm 1 P41182 100.0 2e-85 X-RAY
 2021-12-08 THR A:11 A:12 128.0 0.914 T -46.7 -45.7 98.0 0.7 0.214 B:None:0.207
A:P41182:0.007
 EDO
EDO
VJ2
HOH
 4.882
8.569
9.045
2.792
 N
OG1
C
OG1
 C2
O2
C8
O
3e4u 1 P41182 100.0 2e-85 X-RAY
 2008-12-09 THR A:13 A:12 127.0 0.907 T -72.6 -12.5 127.0 0.907 0.0 HOH
 2.678
 O
 O
THR B:13 B:12 130.0 0.929 T -86.8 -16.6 130.0 0.929 0.0 HOH
 2.525
 O
 O
THR C:13 C:12 117.0 0.836 T -86.4 -1.0 NA NA NA
THR D:13 D:12 138.0 0.986 T -66.8 -21.1 NA NA NA
THR E:13 E:12 124.0 0.886 T -43.9 -41.9 NA NA NA
THR F:13 F:12 132.0 0.943 T -72.6 -22.9 NA NA NA
4u2m 1 Q13105,P41182 99.21 3e-83 X-RAY
 2014-12-10 THR A:139 A:135 126.0 0.9 T -71.7 -14.3 126.0 0.9 0.0 HOH
 2.669
 O
 O
THR B:139 B:135 128.0 0.914 T -74.9 -15.1 NA NA NA
THR C:139 C:135 128.0 0.914 T -73.8 -13.8 NA NA NA
THR D:139 D:135 128.0 0.914 T -71.0 -15.8 NA NA NA
6c3l 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 THR A:14 A:12 127.0 0.907 T -68.1 -16.5 127.0 0.907 0.0 HOH
 2.878
 O
 O
THR B:14 B:12 134.0 0.957 T -69.7 -17.6 NA NA NA
6c3n 1 P41182 96.9 2e-82 X-RAY
 2019-01-16 THR A:14 A:12 116.0 0.829 T -62.6 -31.5 116.0 0.829 0.0 HOH
 3.037
 O
 O
THR B:14 B:12 142.0 1.0 T -70.8 -23.3 142.0 1.0 0.0 HOH
 3.042
 O
 O
6cq1 1 P41182 96.9 2e-82 X-RAY
 2019-03-20 THR A:14 A:12 103.0 0.736 T -70.1 -18.5 103.0 0.736 0.0 F8J
HOH
 9.683
2.742
 C
O
 CAA
O
THR B:14 B:12 104.0 0.743 T -70.3 -18.4 104.0 0.743 0.0 F8J
HOH
 9.584
2.816
 C
O
 CAA
O
6xwf 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 THR A:18 A:12 74.0 0.529 S -75.4 -27.7 74.0 0.529 0.0 MPD
HOH
 8.562
2.787
 CG2
O
 C1
O
6xxs 1 P41182 96.83 1e-80 X-RAY
 2020-12-02 THR A:18 A:12 129.0 0.921 T -55.8 158.8 67.0 0.479 0.442 D:O75376:0.443
THR B:18 B:12 134.0 0.957 T -63.7 -30.2 67.0 0.479 0.478 A:P41182:0.043
C:O75376:0.436
THR G:18 F:12 134.0 0.957 T -63.5 -44.0 60.0 0.429 0.528 F:O75376:0.493
E:P41182:0.036
5mw2 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 THR A:9 A:12 124.0 0.886 T -62.8 -36.7 124.0 0.886 0.0 U52
HOH
 8.643
2.858
 N
O
 C1
O
5mw6 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 THR A:9 A:12 125.0 0.893 T -67.0 -19.0 125.0 0.893 0.0 HOH
 2.778
 O
 O
THR B:9 B:12 119.0 0.85 T -61.6 -33.2 119.0 0.85 0.0 HOH
 2.670
 O
 O
5mwd 1 P41182 97.6 2e-80 X-RAY
 2017-10-04 THR A:9 A:12 127.0 0.907 T -66.4 -20.4 127.0 0.907 0.0 HOH
 2.860
 O
 O
1r28 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 THR A:10 A:12 128.0 0.914 T -63.4 -28.8 128.0 0.914 0.0 HOH
 2.634
 O
 O
THR B:10 B:12 110.0 0.786 T -45.8 -18.0 110.0 0.786 0.0 HOH
 2.655
 O
 O
1r29 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 THR A:10 A:12 131.0 0.936 T -73.5 -15.0 131.0 0.936 0.0 HOH
 2.674
 O
 O
1r2b 1 P41182 97.6 2e-80 X-RAY
 2003-12-23 THR A:10 A:12 144.0 1.0 T -61.0 -21.8 86.0 0.614 0.386 D:Q9Y618:0.414
 HOH
 2.906
 O
 O
THR B:10 B:12 143.0 1.0 T -67.1 -17.0 85.0 0.607 0.393 C:Q9Y618:0.414
 HOH
 2.591
 OG1
 O
3bim 1 P41182 97.6 2e-80 X-RAY
 2008-01-08 THR A:10 A:12 123.0 0.879 T -76.2 -10.3 NA NA NA
THR C:10 B:12 132.0 0.943 T -62.3 -27.8 NA NA NA
THR E:10 C:12 130.0 0.929 T -69.3 -14.4 77.0 0.55 0.379 H:Q6W2J9:0.379
 HOH
 3.195
 N
 O
THR G:10 D:12 132.0 0.943 T -81.5 -23.1 81.0 0.579 0.364 E:P41182:0.007
F:Q6W2J9:0.357
 HOH
 2.773
 N
 O
THR I:10 E:12 121.0 0.864 T -76.4 -19.3 NA NA NA
THR K:10 F:12 132.0 0.943 T -62.8 -9.1 NA NA NA
THR M:10 G:12 126.0 0.9 T -61.7 -15.2 NA NA NA
THR O:10 H:12 128.0 0.914 T -63.9 -28.9 NA NA NA
3lbz 1 P41182 97.6 2e-80 X-RAY
 2010-04-28 THR A:10 A:12 113.0 0.807 T -68.2 -13.6 113.0 0.807 0.0 Z88
Z88
HOH
 6.620
5.473
3.147
 CG2
N
OG1
 OAC
OAB
O
THR B:10 B:12 117.0 0.836 T -61.7 -15.5 117.0 0.836 0.0 HOH
 3.202
 OG1
 O
7bde 1 P41182 97.6 3e-80 X-RAY
 2021-07-28 THR A:10 A:12 123.0 0.879 T -63.7 -33.0 121.0 0.864 0.015 A:P41182:0.014
 HOH
 2.343
 O
 O
6ew8 1 P41182 97.58 1e-79 X-RAY
 2018-10-24 THR A:7 A:12 121.0 0.864 T -62.2 -28.2 121.0 0.864 0.0 HOH
 2.713
 O
 O
6tbt 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 THR A:9 A:12 127.0 0.907 T -62.1 -31.0 84.0 0.6 0.307 D:None:0.307
 HOH
 2.855
 O
 O
THR B:9 B:12 93.0 0.664 T -67.3 -26.0 64.0 0.457 0.207 C:None:0.207
 HOH
 2.788
 O
 O
6tcj 1 P41182 97.58 1e-79 X-RAY
 2021-10-13 THR A:9 A:12 134.0 0.957 T -69.6 -26.2 81.0 0.579 0.378 D:None:0.379
 HOH
 2.913
 O
 O
THR B:9 B:12 129.0 0.921 T -69.1 -27.3 75.0 0.536 0.385 C:None:0.386
 HOH
 2.866
 O
 O
6xxs 3 P41182 97.58 1e-79 X-RAY
 2020-12-02 THR E:9 E:12 137.0 0.979 T -70.8 -32.1 70.0 0.5 0.479 G:P41182:0.029
H:O75376:0.45
6xyx 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 THR A:9 A:12 123.0 0.879 T -74.2 -17.2 60.0 0.429 0.45 D:O75376:0.45
 HOH
 2.558
 O
 O
THR B:9 B:12 132.0 0.943 T -71.6 -18.2 61.0 0.436 0.507 A:P41182:0.021
C:O75376:0.493
 HOH
 2.604
 OG1
 O
6xzz 1 P41182 97.58 1e-79 X-RAY
 2020-12-02 THR A:9 A:12 113.0 0.807 T -59.0 -40.9 52.0 0.371 0.436 B:O75376:0.436
 TFA
HOH
 7.961
2.540
 OG1
OG1
 F3
O
6y17 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 THR A:20 A:12 143.0 1.0 T -71.2 -19.6 80.0 0.571 0.429 C:H0Y786+O75376:0.45
 HOH
 3.021
 N
 O
THR B:20 B:12 132.0 0.943 T -69.1 -21.3 57.0 0.407 0.536 D:H0Y786+O75376:0.536
 HOH
 2.611
 OG1
 O
6zbu 1 O75376,P41182 96.8 1e-79 X-RAY
 2020-12-02 THR A:20 A:12 141.0 1.0 T -72.2 -16.4 65.0 0.464 0.536 D:O75376:0.529
B:O75376+P41182:0.014
 GOL
HOH
 6.804
3.168
 O
N
 O3
O
THR B:20 B:12 139.0 0.993 T -72.8 -17.6 68.0 0.486 0.507 A:O75376+P41182:0.007
C:O75376:0.5
 SO4
GOL
SO4
HOH
 9.400
2.796
3.968
2.951
 N
O
CA
N
 O1
O3
O1
O
THR E:20 E:12 139.0 0.993 T -70.8 -14.8 64.0 0.457 0.536 L:O75376:0.536
 HOH
 3.088
 O
 O
THR F:20 F:12 139.0 0.993 T -69.9 -16.4 76.0 0.543 0.45 G:O75376:0.45
 HOH
 6.845
 O
 O
THR H:20 I:12 143.0 1.0 T -72.0 -17.5 76.0 0.543 0.457 K:O75376:0.479
I:O75376+P41182:0.007
 HOH
 3.062
 O
 O
THR I:20 J:12 140.0 1.0 T -71.6 -16.6 62.0 0.443 0.557 J:O75376:0.557
 HOH
 3.044
 O
 O
5n1z 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 THR A:7 A:12 116.0 0.829 T -67.4 -17.7 116.0 0.829 0.0 HOH
 2.721
 O
 O
5n20 1 P41182 97.56 6e-79 X-RAY
 2017-05-17 THR A:7 A:12 128.0 0.914 T -66.6 -21.8 128.0 0.914 0.0 HOH
 2.763
 O
 O
5n21 1 P41182 97.54 5e-78 X-RAY
 2017-05-17 THR A:6 A:12 119.0 0.85 T -66.7 -19.7 119.0 0.85 0.0 HOH
 2.808
 O
 O
THR B:6 B:12 118.0 0.843 T -64.2 -22.7 NA NA NA
6ew7 1 P41182 97.54 5e-78 X-RAY
 2018-10-24 THR A:6 A:12 121.0 0.864 T -66.7 -13.4 121.0 0.864 0.0 HOH
 2.693
 O
 O
THR B:6 B:12 123.0 0.879 T -67.6 -13.3 123.0 0.879 0.0 HOH
 2.928
 O
 O
4cp3 1 P41182 97.54 5e-78 X-RAY
 2014-03-19 THR A:8 A:12 121.0 0.864 T -71.7 -21.4 119.0 0.85 0.014 B:P41182:0.014
 HOH
 2.793
 O
 O
THR B:8 B:12 98.0 0.7 T -59.9 -22.1 84.0 0.6 0.1 A:P41182:0.1
 HOH
 4.999
 O
 O
6ew6 1 P41182 96.75 2e-77 X-RAY
 2018-10-24 THR A:7 A:12 125.0 0.893 T -66.2 -24.9 125.0 0.893 0.0 HOH
 2.058
 H
 O
5n1x 1 P41182 97.5 2e-76 X-RAY
 2017-05-17 THR A:5 A:12 121.0 0.864 T -70.8 -13.6 121.0 0.864 0.0 HOH
 2.890
 O
 O
5n1x 2 P41182 96.69 5e-76 X-RAY
 2017-05-17 THR B:6 B:12 126.0 0.9 T -70.2 -9.0 NA NA NA
THR C:6 C:12 122.0 0.871 T -69.9 -12.1 NA NA NA
5n1x 3 P41182 97.44 2e-74 X-RAY
 2017-05-17 THR D:5 D:12 126.0 0.9 T -70.3 -11.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p41182-f1 1 P41182 100.0 0.0 THR A:12 A:12 29.0 0.207 H -70.7 -35.3