Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 30691826 . G A CCDS2648.1:NM_003242.5:c.328Gac>Aac_NP_003233.4:p.110D>N Homo sapiens transforming growth factor beta receptor 2 (TGFBR2), transcript variant 1, mRNA.
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1ktz 2 P37173 100.0 9e-84 X-RAY
 2002-02-27 ASP B:73 B:87 147.0 0.98 T 66.2 19.0 147.0 0.98 0.0 HOH
 2.440
 OD2
 O
3kfd 2 P37173 100.0 4e-79 X-RAY
 2010-03-02 ASP C:73 E:87 143.0 0.953 S 85.2 37.0 143.0 0.953 0.0 HOH
 7.206
 N
 O
ASP D:73 F:87 141.0 0.94 S 59.4 49.1 141.0 0.94 0.0
ASP I:73 G:87 139.0 0.927 S 69.5 52.9 NA NA NA
ASP J:73 H:87 139.0 0.927 T 37.2 44.7 NA NA NA
5tx4 1 P37173 100.0 4e-79 X-RAY
 2017-03-01 ASP A:73 A:87 145.0 0.967 T 73.6 23.7 145.0 0.967 0.0 HOH
 2.178
 H
 O
4p7u 1 P37173 99.09 2e-73 X-RAY
 2015-06-24 ASP A:63 A:87 145.0 0.967 T 66.9 23.3 145.0 0.967 0.0 HOH
 2.916
 N
 O
4xjj 1 P37173 99.09 2e-73 X-RAY
 2015-06-24 ASP A:63 A:87 129.0 0.86 T 73.3 18.1 129.0 0.86 0.0 HOH
 2.831
 OD2
 O
1m9z 1 P37173 99.09 2e-73 X-RAY
 2002-09-11 ASP A:62 A:87 141.0 0.94 T 70.3 21.6 141.0 0.94 0.0 HOH
 2.861
 N
 O
2pjy 2 P37173 100.0 4e-72 X-RAY
 2008-02-05 ASP B:69 B:87 153.0 1.0 S 67.4 37.0 153.0 1.0 0.0
5ty4 1 P37173 99.03 3e-68 ELECTRON CRYSTALLOGRAPHY
 2017-04-26 ASP A:64 A:110 157.0 1.0 T 62.9 18.4 157.0 1.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p37173-f1 1 P37173 95.61 0.0 ASP A:110 A:110 151.0 1.0 T 68.2 8.8