Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 3195693 | . | A | C | CCDS2562.1:NM_016302.3:c.902aTt>aGt_NP_057386.2:p.301I>S | Homo sapiens cereblon (CRBN), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6bn7 | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ILE | B:322 | B:301 | 32.0 | 0.183 | -68.8 | 131.4 | 32.0 | 0.183 | 0.0 | |||||||
6bn8 | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-06-06 | ILE | B:322 | B:301 | 34.0 | 0.194 | -67.3 | 126.2 | 34.0 | 0.194 | 0.0 | |||||||
6bn9 | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ILE | B:322 | B:301 | 28.0 | 0.16 | -66.7 | 128.8 | 28.0 | 0.16 | 0.0 | |||||||
6bnb | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ILE | B:322 | B:301 | 10.0 | 0.057 | -76.5 | 127.2 | 10.0 | 0.057 | 0.0 | |||||||
6boy | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ILE | B:322 | B:301 | 34.0 | 0.194 | -69.1 | 131.7 | 34.0 | 0.194 | 0.0 | |||||||
5hxb | 3 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2016-06-29 | ILE | C:265 | Z:301 | 36.0 | 0.206 | -73.9 | 130.4 | 32.0 | 0.183 | 0.023 |
B:Q16531:0.023 |
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ILE | E:265 | C:301 | 22.0 | 0.126 | -73.5 | 130.3 | NA | NA | NA | ||||||||||||||
5v3o | 2 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2017-05-03 | ILE | B:265 | C:301 | 43.0 | 0.246 | -51.7 | 113.9 | 43.0 | 0.246 | 0.0 | |||||||
6uml | 2 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2020-04-15 | ILE | B:265 | C:301 | 32.0 | 0.183 | -72.5 | 129.6 | 32.0 | 0.183 | 0.0 | |||||||
6xk9 | 3 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2020-12-02 | ILE | C:265 | Z:301 | 26.0 | 0.149 | -71.9 | 126.0 | 26.0 | 0.149 | 0.0 | |||||||
ILE | F:265 | C:301 | 30.0 | 0.171 | -71.5 | 126.1 | NA | NA | NA | ||||||||||||||
5fqd | 2 | Q96SW2 | 99.02 | 0.0 |
X-RAY |
2016-02-24 | ILE | B:285 | B:301 | 15.0 | 0.086 | -71.7 | 125.2 | 15.0 | 0.086 | 0.0 |
HOH |
2.691 |
O |
O |
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ILE | E:285 | E:301 | 17.0 | 0.097 | -72.3 | 126.7 | NA | NA | NA | ||||||||||||||
6h0f | 2 | Q96SW2 | 99.02 | 0.0 |
X-RAY |
2018-11-07 | ILE | B:285 | B:301 | 13.0 | 0.074 | -68.4 | 130.1 | 13.0 | 0.074 | 0.0 | |||||||
ILE | E:285 | E:301 | 15.0 | 0.086 | -68.0 | 130.1 | NA | NA | NA | ||||||||||||||
ILE | H:285 | H:301 | 11.0 | 0.063 | -68.2 | 129.7 | NA | NA | NA | ||||||||||||||
ILE | K:285 | K:301 | 17.0 | 0.097 | -68.4 | 130.2 | NA | NA | NA | ||||||||||||||
6h0g | 2 | Q96SW2 | 99.02 | 0.0 |
X-RAY |
2018-11-07 | ILE | B:285 | B:301 | 24.0 | 0.137 | -59.8 | 136.9 | 24.0 | 0.137 | 0.0 | |||||||
ILE | E:285 | E:301 | 26.0 | 0.149 | -58.5 | 137.0 | NA | NA | NA | ||||||||||||||
7lps | 2 | Q96SW2 | 100.0 | 0.0 |
X-RAY |
2021-06-02 | ILE | B:255 | B:301 | 17.0 | 0.097 | -57.4 | 132.1 | 17.0 | 0.097 | 0.0 | |||||||
ILE | E:255 | E:301 | 17.0 | 0.097 | -57.7 | 132.4 | NA | NA | NA | ||||||||||||||
ILE | H:255 | H:301 | 17.0 | 0.097 | -57.4 | 131.7 | NA | NA | NA | ||||||||||||||
ILE | K:255 | K:301 | 18.0 | 0.103 | -57.4 | 132.0 | NA | NA | NA | ||||||||||||||
4tz4 | 2 | Q96SW2 | 100.0 | 0.0 |
X-RAY |
2014-08-06 | ILE | B:254 | C:301 | 32.0 | 0.183 | -72.1 | 130.4 | 32.0 | 0.183 | 0.0 | |||||||
4ci1 | 2 | P0CF65 | 84.08 | 0.0 |
X-RAY |
2014-07-16 | ILE | B:327 | B:303 | 25.0 | 0.143 | -47.4 | 125.5 | 25.0 | 0.143 | 0.0 |
HOH |
8.723 |
CG2 |
O |
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4ci2 | 2 | P0CF65 | 84.08 | 0.0 |
X-RAY |
2014-07-16 | ILE | B:327 | B:303 | 35.0 | 0.2 | -50.1 | 124.9 | 33.0 | 0.189 | 0.011 |
A:Q16531:0.011 |
HOH |
8.890 |
CG2 |
O |
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4ci3 | 2 | P0CF65 | 84.08 | 0.0 |
X-RAY |
2014-07-16 | ILE | B:327 | B:303 | 35.0 | 0.2 | -46.4 | 126.5 | 35.0 | 0.2 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q96sw2-f1 | 1 | Q96SW2 | 100.0 | 0.0 | ILE | A:301 | A:301 | 27.0 | 0.154 | -67.5 | 122.1 |