Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 3215788 | . | C | A | CCDS2562.1:NM_016302.3:c.332cGg>cTg_NP_057386.2:p.111R>L | Homo sapiens cereblon (CRBN), transcript variant 1, mRNA. |
---|---|---|---|---|---|---|---|
|
|
|
|
PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6bn7 | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ARG | B:132 | B:111 | 67.0 | 0.298 | H | -63.3 | -44.2 | 67.0 | 0.298 | 0.0 | ||||||
6bn8 | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-06-06 | ARG | B:132 | B:111 | 73.0 | 0.324 | H | -63.7 | -34.3 | 73.0 | 0.324 | 0.0 | ||||||
6bn9 | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ARG | B:132 | B:111 | 71.0 | 0.316 | H | -61.0 | -45.5 | 71.0 | 0.316 | 0.0 | ||||||
6bnb | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ARG | B:132 | B:111 | 84.0 | 0.373 | H | -60.9 | -27.9 | 84.0 | 0.373 | 0.0 | ||||||
6boy | 2 | Q96SW2 | 97.06 | 0.0 |
X-RAY |
2018-05-30 | ARG | B:132 | B:111 | 66.0 | 0.293 | H | -62.6 | -45.7 | 66.0 | 0.293 | 0.0 | ||||||
5hxb | 3 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2016-06-29 | ARG | C:75 | Z:111 | 72.0 | 0.32 | H | -49.7 | -42.8 | 72.0 | 0.32 | 0.0 | ||||||
ARG | E:75 | C:111 | 79.0 | 0.351 | H | -49.6 | -42.8 | NA | NA | NA | |||||||||||||
5v3o | 2 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2017-05-03 | ARG | B:75 | C:111 | 92.0 | 0.409 | H | -45.8 | -39.0 | 92.0 | 0.409 | 0.0 | ||||||
6uml | 2 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2020-04-15 | ARG | B:75 | C:111 | 36.0 | NA | H | -51.4 | -42.5 | 36.0 | NA | NA | ||||||
6xk9 | 3 | Q96SW2 | 99.75 | 0.0 |
X-RAY |
2020-12-02 | ARG | C:75 | Z:111 | 78.0 | 0.347 | H | -56.7 | -40.5 | 78.0 | 0.347 | 0.0 | ||||||
ARG | F:75 | C:111 | 77.0 | 0.342 | H | -57.0 | -40.8 | NA | NA | NA | |||||||||||||
5fqd | 2 | Q96SW2 | 99.02 | 0.0 |
X-RAY |
2016-02-24 | ARG | B:95 | B:111 | 81.0 | 0.36 | H | -57.2 | -40.1 | 81.0 | 0.36 | 0.0 | ||||||
ARG | E:95 | E:111 | 115.0 | 0.511 | H | -56.7 | -40.1 | NA | NA | NA | |||||||||||||
6h0f | 2 | Q96SW2 | 99.02 | 0.0 |
X-RAY |
2018-11-07 | ARG | B:95 | B:111 | 106.0 | 0.471 | H | -59.4 | -35.0 | 106.0 | 0.471 | 0.0 | ||||||
ARG | E:95 | E:111 | 125.0 | 0.556 | H | -58.8 | -34.9 | NA | NA | NA | |||||||||||||
ARG | H:95 | H:111 | 111.0 | 0.493 | H | -59.4 | -34.6 | NA | NA | NA | |||||||||||||
ARG | K:95 | K:111 | 105.0 | 0.467 | H | -59.3 | -34.7 | NA | NA | NA | |||||||||||||
6h0g | 2 | Q96SW2 | 99.02 | 0.0 |
X-RAY |
2018-11-07 | ARG | B:95 | B:111 | 94.0 | 0.418 | H | -59.6 | -43.8 | 94.0 | 0.418 | 0.0 | ||||||
ARG | E:95 | E:111 | 91.0 | 0.404 | H | -59.6 | -44.0 | NA | NA | NA | |||||||||||||
7lps | 2 | Q96SW2 | 100.0 | 0.0 |
X-RAY |
2021-06-02 | ARG | B:65 | B:111 | 83.0 | 0.369 | H | -62.1 | -40.4 | 83.0 | 0.369 | 0.0 | ||||||
ARG | E:65 | E:111 | 79.0 | 0.351 | H | -61.9 | -40.5 | NA | NA | NA | |||||||||||||
ARG | H:65 | H:111 | 81.0 | 0.36 | H | -62.2 | -40.1 | NA | NA | NA | |||||||||||||
ARG | K:65 | K:111 | 83.0 | 0.369 | H | -62.3 | -40.0 | NA | NA | NA | |||||||||||||
4tz4 | 2 | Q96SW2 | 100.0 | 0.0 |
X-RAY |
2014-08-06 | ARG | B:64 | C:111 | 93.0 | 0.413 | H | -48.8 | -43.9 | 93.0 | 0.413 | 0.0 | ||||||
4ci1 | 2 | P0CF65 | 84.08 | 0.0 |
X-RAY |
2014-07-16 | ARG | B:136 | B:112 | 49.0 | 0.218 | H | -57.4 | -40.1 | 49.0 | 0.218 | 0.0 |
HOH |
6.553 |
NH2 |
O |
||
4ci2 | 2 | P0CF65 | 84.08 | 0.0 |
X-RAY |
2014-07-16 | ARG | B:136 | B:112 | 47.0 | 0.209 | H | -59.9 | -40.6 | 47.0 | 0.209 | 0.0 | ||||||
4ci3 | 2 | P0CF65 | 84.08 | 0.0 |
X-RAY |
2014-07-16 | ARG | B:136 | B:112 | 49.0 | 0.218 | H | -57.9 | -35.9 | 49.0 | 0.218 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q96sw2-f1 | 1 | Q96SW2 | 100.0 | 0.0 | ARG | A:111 | A:111 | 69.0 | 0.307 | H | -55.4 | -39.3 |