Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 41267178 . T A CCDS2694.1:NM_001098209.1:c.762taT>taA_NP_001091679.1:p.254Y>* Homo sapiens catenin beta 1 (CTNNB1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2z6g 1 Q90424 97.06 0.0 X-RAY
 2008-02-12 HIS A:253 A:253 46.0 0.236 H -56.7 -35.6 46.0 0.236 0.0
2z6h 1 P35222 100.0 0.0 X-RAY
 2008-02-12 TYR A:117 A:254 62.0 0.27 H -71.4 -41.2 62.0 0.27 0.0
2gl7 1 P35222 99.82 0.0 X-RAY
 2006-10-31 TYR A:118 A:254 58.0 0.252 H -61.8 -38.2 29.0 0.126 0.126 B:Q9NQB0:0.126
 HOH
 2.956
 OH
 O
TYR D:118 D:254 61.0 0.265 H -60.9 -41.9 NA NA NA
1i7w 1 Q02248 100.0 0.0 X-RAY
 2001-05-09 TYR A:121 A:254 64.0 0.278 H -61.6 -44.2 64.0 0.278 0.0 ZN
HOH
 6.867
3.059
 OH
OH
 ZN
O
TYR C:121 C:254 62.0 0.27 H -63.8 -42.6 62.0 0.27 0.0 ZN
HOH
 6.633
3.382
 OH
CD1
 ZN
O
1i7x 1 Q02248 100.0 0.0 X-RAY
 2001-05-16 TYR A:121 A:254 51.0 0.222 H -60.3 -55.6 51.0 0.222 0.0
TYR C:121 C:254 51.0 0.222 H -50.9 -58.7 29.0 0.126 0.096 D:P09803:0.096
 HOH
 8.031
 CE1
 O
1jpp 1 Q02248 100.0 0.0 X-RAY
 2002-01-16 TYR A:121 A:254 64.0 0.278 H -83.8 -65.7 64.0 0.278 0.0 HOH
 3.918
 OH
 O
TYR B:121 B:254 70.0 0.304 H -90.6 -58.2 NA NA NA
1m1e 1 Q02248 100.0 0.0 X-RAY
 2002-10-16 TYR A:121 A:254 54.0 0.235 H -63.4 -44.6 54.0 0.235 0.0 HOH
 6.947
 N
 O
1v18 1 Q02248 100.0 0.0 X-RAY
 2005-01-12 TYR A:121 A:254 47.0 0.204 H -61.2 -48.5 3.0 0.013 0.191 B:P25054:0.191
 HOH
 6.711
 CE2
 O
4ev8 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TYR A:121 A:254 57.0 0.248 H -65.1 -41.5 57.0 0.248 0.0 HOH
 3.429
 CZ
 O
4ev9 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TYR A:121 A:254 46.0 0.2 H -63.3 -41.7 46.0 0.2 0.0 URE
 3.202
 CD2
 O
4eva 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TYR A:121 A:254 50.0 0.217 H -65.6 -42.7 50.0 0.217 0.0 URE
URE
HOH
 9.415
3.292
8.142
 N
CD2
O
 N1
N2
O
TYR B:121 C:254 45.0 0.196 H -62.2 -44.5 NA NA NA
4evp 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TYR A:121 A:254 37.0 0.161 H -67.8 -41.3 37.0 0.161 0.0 URE
HOH
 2.023
9.702
 OH
O
 N1
O
4evt 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TYR A:121 A:254 54.0 0.235 H -64.1 -35.6 54.0 0.235 0.0 HOH
 6.535
 N
 O
3ouw 1 Q02248 100.0 0.0 X-RAY
 2010-11-24 TYR A:123 A:254 47.0 0.204 H -63.2 -45.5 1.0 0.004 0.2 B:P27782:0.2
3oux 1 Q02248 100.0 0.0 X-RAY
 2010-11-24 TYR A:123 A:254 77.0 0.335 H -60.2 -50.9 13.0 0.057 0.278 B:P27782:0.278
 HOH
 9.669
 N
 O
1jpw 1 P35222 99.63 0.0 X-RAY
 2001-12-05 TYR A:124 A:254 72.0 0.313 H -55.5 -31.2 45.0 0.196 0.117 B:Q9NQB0:0.117
 HOH
 3.167
 OH
 O
TYR C:124 B:254 66.0 0.287 H -64.7 -38.2 NA NA NA
TYR E:124 C:254 66.0 0.287 H -68.6 -36.7 NA NA NA
1qz7 1 P35222 100.0 0.0 X-RAY
 2003-11-18 TYR A:122 A:254 52.0 0.226 H -67.0 -33.4 16.0 0.07 0.156 B:Q9YGY0:0.157
7ar4 1 P35222 99.63 0.0 X-RAY
 2021-04-07 TYR A:125 AAA:254 57.0 0.248 H -61.2 -45.8 57.0 0.248 0.0 HOH
 3.023
 OH
 O
1g3j 1 P35222 100.0 0.0 X-RAY
 2000-12-11 TYR A:122 A:254 62.0 0.27 H -68.0 -41.6 21.0 0.091 0.179 B:P70062:0.178
 HOH
 7.526
 O
 O
TYR C:122 C:254 49.0 NA H -75.1 -41.0 NA NA NA
1th1 1 P35222 100.0 0.0 X-RAY
 2004-09-07 TYR A:122 A:254 52.0 0.226 H -78.6 -44.3 3.0 0.013 0.213 C:P25054:0.213
TYR B:122 B:254 53.0 0.23 H -70.4 -44.7 NA NA NA
1jdh 1 P35222 100.0 0.0 X-RAY
 2001-12-05 TYR A:120 A:254 55.0 0.239 H -61.5 -43.2 30.0 0.13 0.109 B:Q9NQB0:0.109
 HOH
 3.163
 OH
 O
3tx7 1 P35222 100.0 0.0 X-RAY
 2011-12-14 TYR A:118 A:254 47.0 0.204 H -59.5 -49.4 47.0 0.204 0.0
1t08 1 P35222 100.0 0.0 X-RAY
 2004-10-12 TYR A:109 A:254 58.0 0.252 H -64.6 -45.5 58.0 0.252 0.0 HOH
 5.728
 OH
 O
4djs 1 P35222 100.0 0.0 X-RAY
 2012-10-17 TYR A:107 A:254 58.0 0.252 H -58.0 -43.3 23.0 0.1 0.152 B:None:0.152
2bct 1 Q02248 100.0 0.0 X-RAY
 1997-10-15 TYR A:105 A:254 54.0 0.235 H -48.7 -45.4 54.0 0.235 0.0
1luj 1 P35222 100.0 0.0 X-RAY
 2002-10-16 TYR A:105 A:254 61.0 0.265 H -72.5 -40.5 61.0 0.265 0.0
3bct 1 Q02248 100.0 0.0 X-RAY
 1997-11-19 TYR A:62 A:254 8.0 NA H -62.0 -44.2 8.0 NA NA
3sla 1 P35222 100.0 1e-112 X-RAY
 2012-02-29 TYR A:116 A:254 39.0 0.17 H -77.2 -47.2 39.0 0.17 0.0 HOH
 4.322
 OH
 O
TYR B:116 B:254 40.0 0.174 H -65.0 -50.0 NA NA NA
TYR C:116 C:254 45.0 0.196 H -65.3 -49.6 NA NA NA
TYR D:116 D:254 36.0 0.157 H -72.1 -33.9 NA NA NA
TYR E:116 E:254 42.0 0.183 H -65.7 -45.9 NA NA NA
3sl9 1 P35222 100.0 2e-111 X-RAY
 2012-02-29 TYR A:116 A:254 49.0 0.213 H -68.2 -32.8 49.0 0.213 0.0 HOH
 4.338
 OH
 O
TYR C:116 B:254 52.0 0.226 H -61.2 -40.9 NA NA NA
TYR E:116 E:254 46.0 0.2 H -64.3 -42.1 NA NA NA
TYR G:116 G:254 51.0 0.222 H -68.0 -42.1 NA NA NA
7afw 1 P35222 100.0 2e-111 X-RAY
 2020-12-16 TYR A:116 A:254 49.0 0.213 H -56.9 -44.8 49.0 0.213 0.0 R9Q
HOH
 9.675
2.681
 CD2
OH
 O10
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35222-f1 1 P35222 100.0 0.0 TYR A:254 A:254 58.0 0.252 H -64.6 -44.5