Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 41268776 | . | G | A | CCDS2694.1:NM_001098209.1:c.1014tgG>tgA_NP_001091679.1:p.338W>* | Homo sapiens catenin beta 1 (CTNNB1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2z6g | 1 | Q90424 | 97.06 | 0.0 |
X-RAY |
2008-02-12 | TRP | A:337 | A:337 | 48.0 | 0.188 | H | -51.1 | -62.2 | 48.0 | 0.188 | 0.0 | ||||||
2z6h | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2008-02-12 | TRP | A:201 | A:338 | 53.0 | 0.208 | H | -71.7 | -44.6 | 53.0 | 0.208 | 0.0 | ||||||
2gl7 | 1 | P35222 | 99.82 | 0.0 |
X-RAY |
2006-10-31 | TRP | A:202 | A:338 | 55.0 | 0.216 | H | -63.2 | -54.2 | 24.0 | 0.094 | 0.122 |
B:Q9NQB0:0.122 |
HOH |
2.945 |
NE1 |
O |
|
TRP | D:202 | D:338 | 53.0 | 0.208 | H | -69.0 | -55.6 | NA | NA | NA | |||||||||||||
1i7w | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2001-05-09 | TRP | A:205 | A:338 | 53.0 | 0.208 | H | -66.0 | -46.7 | 19.0 | 0.075 | 0.133 |
B:P09803:0.133 |
CL HOH |
3.902 2.874 |
CZ3 NE1 |
CL O |
|
TRP | C:205 | C:338 | 47.0 | 0.184 | H | -71.0 | -54.0 | 12.0 | 0.047 | 0.137 |
D:P09803:0.137 |
CL HOH |
4.222 3.144 |
CZ3 NE1 |
CL O |
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1i7x | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2001-05-16 | TRP | A:205 | A:338 | 45.0 | 0.176 | H | -62.4 | -52.6 | 45.0 | 0.176 | 0.0 |
HOH |
3.015 |
NE1 |
O |
||
TRP | C:205 | C:338 | 53.0 | 0.208 | H | -59.4 | -61.2 | 53.0 | 0.208 | 0.0 |
HOH |
3.014 |
NE1 |
O |
|||||||||
1jpp | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2002-01-16 | TRP | A:205 | A:338 | 50.0 | 0.196 | H | -78.1 | -48.7 | 50.0 | 0.196 | 0.0 |
HOH |
5.806 |
CZ2 |
O |
||
TRP | B:205 | B:338 | 48.0 | 0.188 | H | -72.7 | -48.9 | NA | NA | NA | |||||||||||||
1m1e | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | TRP | A:205 | A:338 | 47.0 | 0.184 | H | -65.0 | -50.0 | 47.0 | 0.184 | 0.0 |
HOH |
3.103 |
NE1 |
O |
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1v18 | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2005-01-12 | TRP | A:205 | A:338 | 54.0 | 0.212 | H | -59.7 | -56.1 | 42.0 | 0.165 | 0.047 |
B:P25054:0.047 |
HOH |
2.738 |
NE1 |
O |
|
4ev8 | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TRP | A:205 | A:338 | 39.0 | 0.153 | H | -62.6 | -50.5 | 39.0 | 0.153 | 0.0 |
URE URE HOH |
7.651 8.408 2.776 |
N CZ2 NE1 |
N1 N1 O |
||
4ev9 | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TRP | A:205 | A:338 | 42.0 | 0.165 | H | -63.7 | -51.5 | 42.0 | 0.165 | 0.0 |
URE URE HOH |
7.572 8.368 2.871 |
N CZ2 NE1 |
N1 N1 O |
||
4eva | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TRP | A:205 | A:338 | 42.0 | 0.165 | H | -64.4 | -52.3 | 42.0 | 0.165 | 0.0 |
URE URE HOH |
7.724 9.055 2.870 |
N CD1 NE1 |
N1 N2 O |
||
TRP | B:205 | C:338 | 56.0 | 0.22 | H | -65.6 | -50.9 | NA | NA | NA | |||||||||||||
4evp | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TRP | A:205 | A:338 | 51.0 | 0.2 | H | -64.7 | -49.8 | 51.0 | 0.2 | 0.0 |
URE URE HOH |
7.817 7.709 4.269 |
N CZ2 NE1 |
N1 N1 O |
||
4evt | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TRP | A:205 | A:338 | 46.0 | 0.18 | H | -66.2 | -50.8 | 46.0 | 0.18 | 0.0 |
URE URE URE URE URE HOH |
7.808 5.255 6.781 8.646 4.893 3.171 |
N NE1 CD1 CD1 NE1 NE1 |
N1 O N2 O N1 O |
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3ouw | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2010-11-24 | TRP | A:207 | A:338 | 54.0 | 0.212 | H | -84.2 | -68.3 | 40.0 | 0.157 | 0.055 |
B:P27782:0.055 |
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3oux | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2010-11-24 | TRP | A:207 | A:338 | 59.0 | 0.231 | H | -73.8 | -52.9 | 37.0 | 0.145 | 0.086 |
B:P27782:0.086 |
HOH |
4.718 |
O |
O |
|
1jpw | 1 | P35222 | 99.63 | 0.0 |
X-RAY |
2001-12-05 | TRP | A:208 | A:338 | 62.0 | 0.243 | H | -64.0 | -59.8 | 39.0 | 0.153 | 0.09 |
B:Q9NQB0:0.09 |
HOH |
4.219 |
O |
O |
|
TRP | C:208 | B:338 | 60.0 | 0.235 | H | -64.8 | -66.0 | NA | NA | NA | |||||||||||||
TRP | E:208 | C:338 | 60.0 | 0.235 | H | -68.5 | -63.1 | NA | NA | NA | |||||||||||||
1qz7 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2003-11-18 | TRP | A:206 | A:338 | 55.0 | 0.216 | H | -59.6 | -53.5 | 26.0 | 0.102 | 0.114 |
B:Q9YGY0:0.114 |
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7ar4 | 1 | P35222 | 99.63 | 0.0 |
X-RAY |
2021-04-07 | TRP | A:209 | AAA:338 | 57.0 | 0.224 | H | -61.7 | -56.5 | 57.0 | 0.224 | 0.0 |
HOH |
4.674 |
HZ3 |
O |
||
1g3j | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2000-12-11 | TRP | A:206 | A:338 | 56.0 | 0.22 | H | -64.7 | -52.2 | 14.0 | 0.055 | 0.165 |
B:P70062:0.165 |
HOH |
5.845 |
CH2 |
O |
|
TRP | C:206 | C:338 | 0.0 | NA | H | -65.8 | -51.0 | NA | NA | NA | |||||||||||||
1th1 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2004-09-07 | TRP | A:206 | A:338 | 63.0 | 0.247 | H | -66.7 | -46.0 | 29.0 | 0.114 | 0.133 |
C:P25054:0.133 |
|||||
TRP | B:206 | B:338 | 59.0 | 0.231 | H | -66.6 | -49.6 | NA | NA | NA | |||||||||||||
1jdh | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2001-12-05 | TRP | A:204 | A:338 | 61.0 | 0.239 | H | -65.0 | -52.3 | 23.0 | 0.09 | 0.149 |
B:Q9NQB0:0.149 |
HOH |
2.793 |
NE1 |
O |
|
3tx7 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2011-12-14 | TRP | A:202 | A:338 | 50.0 | 0.196 | H | -62.7 | -53.6 | 50.0 | 0.196 | 0.0 | ||||||
1t08 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2004-10-12 | TRP | A:193 | A:338 | 50.0 | 0.196 | H | -66.0 | -52.3 | 50.0 | 0.196 | 0.0 |
HOH |
2.836 |
NE1 |
O |
||
4djs | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2012-10-17 | TRP | A:191 | A:338 | 52.0 | 0.204 | H | -58.5 | -55.0 | 28.0 | 0.11 | 0.094 |
B:None:0.094 |
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2bct | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
1997-10-15 | TRP | A:189 | A:338 | 52.0 | 0.204 | H | -61.8 | -54.7 | 52.0 | 0.204 | 0.0 | ||||||
1luj | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | TRP | A:189 | A:338 | 44.0 | 0.173 | H | -70.6 | -54.4 | 44.0 | 0.173 | 0.0 | ||||||
3bct | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
1997-11-19 | TRP | A:146 | A:338 | 38.0 | 0.149 | H | -61.0 | -54.8 | 38.0 | 0.149 | 0.0 |
URE HOH |
7.778 2.856 |
N NE1 |
N1 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p35222-f1 | 1 | P35222 | 100.0 | 0.0 | TRP | A:338 | A:338 | 53.0 | 0.208 | H | -65.4 | -46.9 |