Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 41275346 . G A CCDS2694.1:NM_001098209.1:c.1512tgG>tgA_NP_001091679.1:p.504W>* Homo sapiens catenin beta 1 (CTNNB1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2z6g 1 Q90424 97.06 0.0 X-RAY
 2008-02-12 TRP A:503 A:503 53.0 0.208 H -42.0 -52.4 53.0 0.208 0.0
2z6h 1 P35222 100.0 0.0 X-RAY
 2008-02-12 TRP A:367 A:504 17.0 0.067 H -45.4 -41.3 17.0 0.067 0.0 HOH
 5.034
 C
 O
2gl7 1 P35222 99.82 0.0 X-RAY
 2006-10-31 TRP A:368 A:504 14.0 0.055 H -64.3 -33.5 14.0 0.055 0.0 HOH
 3.565
 NE1
 O
TRP D:368 D:504 39.0 0.153 H -68.8 -38.6 NA NA NA
1i7w 1 Q02248 100.0 0.0 X-RAY
 2001-05-09 TRP A:371 A:504 85.0 0.333 H -49.8 -45.1 85.0 0.333 0.0 HOH
 3.229
 N
 O
TRP C:371 C:504 87.0 0.341 H -54.5 -44.1 87.0 0.341 0.0 HOH
 3.058
 N
 O
1i7x 1 Q02248 100.0 0.0 X-RAY
 2001-05-16 TRP A:371 A:504 52.0 0.204 H -40.7 -56.4 52.0 0.204 0.0
TRP C:371 C:504 32.0 0.125 H -53.6 -48.8 32.0 0.125 0.0
1jpp 1 Q02248 100.0 0.0 X-RAY
 2002-01-16 TRP A:371 A:504 21.0 0.082 H -59.4 -49.9 21.0 0.082 0.0
TRP B:371 B:504 25.0 0.098 H -59.2 -48.8 NA NA NA
1m1e 1 Q02248 100.0 0.0 X-RAY
 2002-10-16 TRP A:371 A:504 50.0 0.196 H -51.2 -46.8 50.0 0.196 0.0 HOH
 3.030
 CH2
 O
1v18 1 Q02248 100.0 0.0 X-RAY
 2005-01-12 TRP A:371 A:504 26.0 0.102 H -46.9 -45.7 26.0 0.102 0.0 HOH
 4.162
 CE2
 O
4ev8 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TRP A:371 A:504 93.0 0.365 H -56.3 -44.2 93.0 0.365 0.0 URE
HOH
 3.758
3.010
 CZ2
N
 O
O
4ev9 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TRP A:371 A:504 90.0 0.353 H -57.3 -43.2 90.0 0.353 0.0 URE
HOH
 3.541
3.223
 CD1
CH2
 O
O
4eva 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TRP A:371 A:504 95.0 0.373 H -59.1 -42.7 95.0 0.373 0.0 URE
URE
URE
URE
HOH
 4.101
3.801
3.143
8.276
3.340
 CZ2
CE2
N
O
CH2
 O
N2
N2
N2
O
TRP B:371 C:504 92.0 0.361 H -59.8 -42.2 NA NA NA
4evp 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TRP A:371 A:504 96.0 0.376 H -52.6 -46.4 96.0 0.376 0.0 URE
URE
URE
URE
URE
HOH
 3.836
9.734
5.765
3.217
4.550
3.326
 CE2
N
N
N
CZ2
CH2
 N1
N1
O
O
C
O
4evt 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 TRP A:371 A:504 91.0 0.357 H -54.6 -43.2 91.0 0.357 0.0 URE
URE
URE
URE
URE
URE
HOH
 7.395
3.507
4.123
4.107
6.635
3.037
3.173
 O
CB
CE2
CZ2
N
CD1
CH2
 N2
O
N1
N1
O
N2
O
3ouw 1 Q02248 100.0 0.0 X-RAY
 2010-11-24 TRP A:373 A:504 67.0 0.263 H -47.6 -45.3 67.0 0.263 0.0
3oux 1 Q02248 100.0 0.0 X-RAY
 2010-11-24 TRP A:373 A:504 76.0 0.298 H -51.4 -44.3 76.0 0.298 0.0 HOH
 5.642
 O
 O
1jpw 1 P35222 99.63 0.0 X-RAY
 2001-12-05 TRP A:374 A:504 38.0 0.149 H -63.8 -46.0 38.0 0.149 0.0 HOH
 5.819
 N
 O
TRP C:374 B:504 37.0 0.145 H -65.3 -38.8 NA NA NA
TRP E:374 C:504 37.0 0.145 H -67.0 -39.4 NA NA NA
1qz7 1 P35222 100.0 0.0 X-RAY
 2003-11-18 TRP A:372 A:504 36.0 0.141 H -57.7 -43.3 36.0 0.141 0.0 HOH
 4.646
 N
 O
7ar4 1 P35222 99.63 0.0 X-RAY
 2021-04-07 TRP A:375 AAA:504 10.0 0.039 H -61.2 -44.4 10.0 0.039 0.0 HOH
 9.000
 HB3
 O
1g3j 1 P35222 100.0 0.0 X-RAY
 2000-12-11 TRP A:372 A:504 36.0 0.141 H -43.4 -41.8 36.0 0.141 0.0 HOH
 3.418
 CZ2
 O
TRP C:372 C:504 33.0 0.129 H -48.9 -47.4 NA NA NA
1th1 1 P35222 100.0 0.0 X-RAY
 2004-09-07 TRP A:372 A:504 54.0 0.212 H -54.0 -43.9 54.0 0.212 0.0 HOH
 3.074
 CH2
 O
TRP B:372 B:504 40.0 0.157 H -55.5 -39.8 NA NA NA
1jdh 1 P35222 100.0 0.0 X-RAY
 2001-12-05 TRP A:370 A:504 47.0 0.184 H -49.4 -43.7 47.0 0.184 0.0 HOH
 3.565
 CZ2
 O
3tx7 1 P35222 100.0 0.0 X-RAY
 2011-12-14 TRP A:368 A:504 18.0 0.071 H -55.6 -42.7 18.0 0.071 0.0
1t08 1 P35222 100.0 0.0 X-RAY
 2004-10-12 TRP A:359 A:504 55.0 0.216 H -48.6 -51.1 55.0 0.216 0.0 HOH
 3.284
 CH2
 O
4djs 1 P35222 100.0 0.0 X-RAY
 2012-10-17 TRP A:357 A:504 38.0 0.149 H -55.7 -47.4 38.0 0.149 0.0
2bct 1 Q02248 100.0 0.0 X-RAY
 1997-10-15 TRP A:355 A:504 97.0 0.38 H -10.6 -68.6 97.0 0.38 0.0
1luj 1 P35222 100.0 0.0 X-RAY
 2002-10-16 TRP A:355 A:504 76.0 0.298 H -51.2 -43.6 76.0 0.298 0.0
3bct 1 Q02248 100.0 0.0 X-RAY
 1997-11-19 TRP A:312 A:504 94.0 0.369 H -52.4 -43.8 94.0 0.369 0.0 HOH
 3.360
 CH2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35222-f1 1 P35222 100.0 0.0 TRP A:504 A:504 21.0 0.082 H -62.3 -38.6