Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 41278086 | . | T | A | CCDS2694.1:NM_001098209.1:c.1962taT>taA_NP_001091679.1:p.654Y>* | Homo sapiens catenin beta 1 (CTNNB1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2z6g | 1 | Q90424 | 97.06 | 0.0 |
X-RAY |
2008-02-12 | TYR | A:653 | A:653 | 49.0 | 0.213 | H | -50.5 | -43.4 | 49.0 | 0.213 | 0.0 | ||||||
2z6h | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2008-02-12 | TYR | A:517 | A:654 | 65.0 | 0.283 | H | -62.1 | -39.3 | 65.0 | 0.283 | 0.0 | ||||||
2gl7 | 1 | P35222 | 99.82 | 0.0 |
X-RAY |
2006-10-31 | TYR | A:518 | A:654 | 59.0 | 0.257 | H | -64.3 | -36.8 | 59.0 | 0.257 | 0.0 |
HOH |
7.402 |
CE2 |
O |
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TYR | D:518 | D:654 | 91.0 | 0.396 | H | -74.4 | -29.7 | NA | NA | NA | |||||||||||||
1i7w | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2001-05-09 | TYR | A:521 | A:654 | 52.0 | 0.226 | H | -67.4 | -40.0 | 3.0 | 0.013 | 0.213 |
B:P09803:0.213 |
HOH |
3.525 |
CE1 |
O |
|
TYR | C:521 | C:654 | 61.0 | 0.265 | H | -64.2 | -42.0 | 2.0 | 0.009 | 0.256 |
D:P09803:0.257 |
HOH |
3.522 |
CE1 |
O |
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1i7x | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2001-05-16 | TYR | A:521 | A:654 | 52.0 | 0.226 | H | -56.6 | -45.3 | 3.0 | 0.013 | 0.213 |
B:P09803:0.213 |
HOH |
4.729 |
OH |
O |
|
TYR | C:521 | C:654 | 53.0 | 0.23 | H | -77.6 | -59.9 | 4.0 | 0.017 | 0.213 |
D:P09803:0.213 |
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1jpp | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2002-01-16 | TYR | A:521 | A:654 | 65.0 | 0.283 | H | -79.8 | -28.9 | 65.0 | 0.283 | 0.0 |
HOH |
5.488 |
N |
O |
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TYR | B:521 | B:654 | 68.0 | 0.296 | H | -82.9 | -24.8 | NA | NA | NA | |||||||||||||
1m1e | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | TYR | A:521 | A:654 | 58.0 | 0.252 | H | -61.1 | -43.3 | 10.0 | 0.043 | 0.209 |
B:Q9NSA3:0.209 |
HOH |
2.631 |
OH |
O |
|
1v18 | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2005-01-12 | TYR | A:521 | A:654 | 54.0 | 0.235 | H | -61.5 | -44.8 | 54.0 | 0.235 | 0.0 |
HOH |
4.337 |
CE1 |
O |
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4ev8 | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TYR | A:521 | A:654 | 63.0 | 0.274 | H | -66.6 | -40.3 | 63.0 | 0.274 | 0.0 |
URE HOH |
9.204 2.612 |
N OH |
N2 O |
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4ev9 | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TYR | A:521 | A:654 | 64.0 | 0.278 | H | -71.0 | -43.4 | 64.0 | 0.278 | 0.0 |
URE URE URE URE HOH |
9.115 8.603 8.130 9.497 2.698 |
N CE2 OH CE2 OH |
N2 N2 N2 N2 O |
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4eva | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TYR | A:521 | A:654 | 61.0 | 0.265 | H | -65.6 | -42.4 | 61.0 | 0.265 | 0.0 |
URE URE URE URE HOH |
9.154 8.665 7.315 6.820 2.600 |
N CE2 OH OH OH |
N2 O O N1 O |
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TYR | B:521 | C:654 | 61.0 | 0.265 | H | -64.9 | -42.1 | NA | NA | NA | |||||||||||||
4evp | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TYR | A:521 | A:654 | 67.0 | 0.291 | H | -69.5 | -42.3 | 67.0 | 0.291 | 0.0 |
URE URE URE URE HOH |
9.073 6.599 3.253 9.816 2.572 |
N OH CE2 OH OH |
O N2 N1 O O |
||
4evt | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2013-05-01 | TYR | A:521 | A:654 | 58.0 | 0.252 | H | -67.3 | -41.6 | 58.0 | 0.252 | 0.0 |
URE URE URE URE HOH |
9.033 5.936 9.903 3.154 3.293 |
N OH CE1 CE2 CE1 |
N2 N2 N2 N2 O |
||
3ouw | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2010-11-24 | TYR | A:523 | A:654 | 76.0 | 0.33 | H | -57.5 | -41.4 | 41.0 | 0.178 | 0.152 |
B:P27782:0.152 |
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3oux | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
2010-11-24 | TYR | A:523 | A:654 | 76.0 | 0.33 | H | -66.3 | -43.2 | 40.0 | 0.174 | 0.156 |
B:P27782:0.157 |
HOH |
3.992 |
CE1 |
O |
|
1jpw | 1 | P35222 | 99.63 | 0.0 |
X-RAY |
2001-12-05 | TYR | A:524 | A:654 | 53.0 | 0.23 | H | -71.0 | -25.6 | 53.0 | 0.23 | 0.0 |
HOH |
4.938 |
OH |
O |
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TYR | C:524 | B:654 | 58.0 | 0.252 | H | -70.3 | -36.6 | NA | NA | NA | |||||||||||||
TYR | E:524 | C:654 | 59.0 | 0.257 | H | -71.3 | -37.9 | NA | NA | NA | |||||||||||||
1qz7 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2003-11-18 | TYR | A:522 | A:654 | 64.0 | 0.278 | H | -63.0 | -41.5 | 64.0 | 0.278 | 0.0 | ||||||
7ar4 | 1 | P35222 | 99.63 | 0.0 |
X-RAY |
2021-04-07 | TYR | A:525 | AAA:654 | 58.0 | 0.252 | H | -68.9 | -46.9 | 58.0 | 0.252 | 0.0 |
HOH |
4.002 |
HE2 |
O |
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1g3j | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2000-12-11 | TYR | A:522 | A:654 | 48.0 | 0.209 | H | -60.4 | -45.0 | 31.0 | 0.135 | 0.074 |
B:P70062:0.074 |
HOH |
3.668 |
CE1 |
O |
|
TYR | C:522 | C:654 | 58.0 | 0.252 | H | -61.7 | -40.3 | NA | NA | NA | |||||||||||||
1th1 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2004-09-07 | TYR | A:522 | A:654 | 59.0 | 0.257 | H | -66.0 | -36.5 | 8.0 | 0.035 | 0.222 |
C:P25054:0.222 |
HOH |
6.119 |
OH |
O |
|
TYR | B:522 | B:654 | 54.0 | 0.235 | H | -68.4 | -40.4 | NA | NA | NA | |||||||||||||
1jdh | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2001-12-05 | TYR | A:520 | A:654 | 58.0 | 0.252 | H | -60.3 | -40.9 | 58.0 | 0.252 | 0.0 |
HOH |
4.160 |
OH |
O |
||
3tx7 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2011-12-14 | TYR | A:518 | A:654 | 57.0 | 0.248 | H | -61.7 | -43.8 | 57.0 | 0.248 | 0.0 | ||||||
1t08 | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2004-10-12 | TYR | A:509 | A:654 | 54.0 | 0.235 | H | -62.5 | -43.8 | 9.0 | 0.039 | 0.196 |
B:Q9NSA3:0.196 |
HOH |
2.696 |
OH |
O |
|
4djs | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2012-10-17 | TYR | A:507 | A:654 | 77.0 | 0.335 | H | -77.1 | -45.1 | 77.0 | 0.335 | 0.0 | ||||||
2bct | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
1997-10-15 | TYR | A:505 | A:654 | 63.0 | 0.274 | H | -64.1 | -46.4 | 63.0 | 0.274 | 0.0 | ||||||
1luj | 1 | P35222 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | TYR | A:505 | A:654 | 64.0 | 0.278 | H | -57.5 | -44.3 | 0.0 | 0.0 | 0.278 |
B:Q9JJN6:0.278 |
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3bct | 1 | Q02248 | 100.0 | 0.0 |
X-RAY |
1997-11-19 | TYR | A:462 | A:654 | 65.0 | 0.283 | H | -74.4 | -37.6 | 65.0 | 0.283 | 0.0 |
URE HOH |
8.945 2.585 |
N OH |
N2 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p35222-f1 | 1 | P35222 | 100.0 | 0.0 | TYR | A:654 | A:654 | 42.0 | 0.183 | H | -65.9 | -39.8 |