Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 48637071 | . | A | C | CCDS2774.1:NM_003365.2:c.1375Tat>Gat_NP_003356.2:p.459Y>D | Homo sapiens ubiquinol-cytochrome c reductase core protein I (UQCRC1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5xte | 11 | P31930 | 100.0 | 0.0 |
EM |
2017-08-30 | TYR | K:425 | L:459 | 40.0 | 0.174 | E | -90.2 | 132.6 | 40.0 | 0.174 | 0.0 | ||||||
TYR | V:425 | Y:459 | 27.0 | 0.117 | E | -102.3 | 129.2 | 27.0 | 0.117 | 0.0 | |||||||||||||
5xth | 68 | P31930 | 100.0 | 0.0 |
EM |
2017-09-13 | TYR | QB:425 | AL:459 | 39.0 | 0.17 | E | -90.2 | 132.6 | 39.0 | 0.17 | 0.0 | ||||||
TYR | BC:425 | AY:459 | 27.0 | 0.117 | E | -102.3 | 129.2 | 27.0 | 0.117 | 0.0 | |||||||||||||
5xti | 68 | P31930 | 100.0 | 0.0 |
EM |
2017-09-13 | TYR | QB:425 | AL:459 | 39.0 | 0.17 | E | -90.2 | 132.6 | 39.0 | 0.17 | 0.0 | ||||||
TYR | BC:425 | AY:459 | 28.0 | 0.122 | E | -102.3 | 129.2 | 28.0 | 0.122 | 0.0 | |||||||||||||
1sqb | 1 | P31800 | 89.17 | 0.0 |
X-RAY |
2004-09-07 | PHE | A:459 | A:425 | 16.0 | 0.076 | E | -145.1 | 138.8 | 16.0 | 0.076 | 0.0 |
HOH |
4.992 |
CE1 |
O |
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1sqp | 1 | P31800 | 89.17 | 0.0 |
X-RAY |
2005-11-01 | PHE | A:459 | A:425 | 14.0 | 0.067 | E | -155.8 | 136.7 | 14.0 | 0.067 | 0.0 |
HOH |
3.899 |
CZ |
O |
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4d6t | 1 | P31800 | 89.17 | 0.0 |
X-RAY |
2015-01-14 | PHE | A:459 | A:425 | 16.0 | 0.076 | E | -129.9 | 128.2 | 16.0 | 0.076 | 0.0 | ||||||
PHE | K:459 | N:425 | 15.0 | 0.071 | E | -127.9 | 125.3 | NA | NA | NA | |||||||||||||
4d6u | 1 | P31800 | 89.17 | 0.0 |
X-RAY |
2015-01-14 | PHE | A:459 | A:425 | 14.0 | 0.067 | E | -127.3 | 126.7 | 14.0 | 0.067 | 0.0 | ||||||
6fo0 | 1 | P31800 | 89.17 | 0.0 |
EM |
2018-02-28 | PHE | A:459 | N:425 | 18.0 | 0.086 | E | -150.7 | 95.4 | 18.0 | 0.086 | 0.0 | ||||||
PHE | K:459 | A:425 | 19.0 | 0.09 | E | -150.6 | 95.4 | 19.0 | 0.09 | 0.0 | |||||||||||||
6fo2 | 1 | P31800 | 89.17 | 0.0 |
EM |
2018-02-28 | PHE | A:459 | N:425 | 26.0 | 0.124 | E | -141.3 | 94.5 | 26.0 | 0.124 | 0.0 | ||||||
PHE | K:459 | A:425 | 28.0 | 0.133 | E | -141.3 | 94.6 | 28.0 | 0.133 | 0.0 | |||||||||||||
6fo6 | 2 | P31800 | 89.17 | 0.0 |
EM |
2018-02-28 | PHE | B:459 | A:425 | 8.0 | 0.038 | E | -158.3 | 110.5 | 8.0 | 0.038 | 0.0 | ||||||
PHE | K:459 | N:425 | 15.0 | 0.071 | E | -158.3 | 110.5 | 15.0 | 0.071 | 0.0 | |||||||||||||
4d6u | 10 | P31800 | 88.96 | 0.0 |
X-RAY |
2015-01-14 | PHE | K:459 | N:425 | 15.0 | 0.071 | E | -126.7 | 127.8 | NA | NA | NA | ||||||
5okd | 1 | P31800 | 88.75 | 0.0 |
X-RAY |
2018-02-28 | PHE | A:459 | A:425 | 17.0 | 0.081 | E | -148.0 | 135.9 | 17.0 | 0.081 | 0.0 |
HOH |
4.459 |
CZ |
O |
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5gup | 45 | F1SKM0 | 88.75 | 0.0 |
EM |
2017-03-29 | LEU | UA:459 | u:459 | 5.0 | 0.029 | E | -147.9 | 105.8 | 5.0 | 0.029 | 0.0 | ||||||
LEU | FB:459 | 5:459 | 5.0 | 0.029 | E | -147.3 | 137.9 | 5.0 | 0.029 | 0.0 | |||||||||||||
5j7y | 51 | W5Q5G6 | 91.48 | 0.0 |
EM |
2016-09-21 | PHE | CB:425 | AA:425 | 33.0 | NA | -134.4 | 127.4 | 16.0 | NA | NA |
KB:W5P2X9:NA |
||||||
PHE | NB:425 | AL:425 | 33.0 | NA | -134.3 | 127.4 | 16.0 | NA | NA |
VB:W5P2X9:NA |
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5j8k | 51 | W5Q5G6 | 91.48 | 0.0 |
EM |
2016-09-21 | PHE | CB:425 | AA:425 | 33.0 | NA | -134.4 | 127.4 | 15.0 | NA | NA |
KB:W5P2X9:NA |
||||||
PHE | NB:425 | AL:425 | 33.0 | NA | -134.3 | 127.3 | 16.0 | NA | NA |
VB:W5P2X9:NA |
|||||||||||||
6q9e | 1 | W5Q5G6 | 91.48 | 0.0 |
EM |
2019-08-21 | PHE | A:425 | a1:425 | 22.0 | 0.105 | E | -141.3 | 124.0 | 18.0 | 0.086 | 0.019 |
G:W5PUP9:0.019 |
|||||
PHE | K:425 | a3:425 | 18.0 | 0.086 | E | -146.1 | 124.2 | 18.0 | 0.086 | 0.0 | |||||||||||||
6qbx | 1 | W5Q5G6 | 91.48 | 0.0 |
EM |
2019-08-21 | PHE | A:425 | a1:425 | 21.0 | 0.1 | E | -144.8 | 116.8 | 21.0 | 0.1 | 0.0 | ||||||
PHE | K:425 | a3:425 | 19.0 | 0.09 | E | -142.0 | 126.0 | 19.0 | 0.09 | 0.0 | |||||||||||||
6qc2 | 29 | ? | 91.48 | 0.0 |
EM |
2019-08-21 | PHE | CA:425 | a1:425 | 17.0 | 0.081 | E | -142.7 | 121.3 | 17.0 | 0.081 | 0.0 | ||||||
PHE | MA:425 | a3:425 | 25.0 | 0.119 | E | -148.2 | 120.0 | 25.0 | 0.119 | 0.0 | |||||||||||||
6qc3 | 1 | ? | 91.48 | 0.0 |
EM |
2019-08-21 | PHE | A:425 | a1:425 | 18.0 | 0.086 | E | -146.0 | 122.9 | 18.0 | 0.086 | 0.0 | ||||||
PHE | K:425 | a3:425 | 20.0 | 0.095 | E | -135.9 | 130.0 | 20.0 | 0.095 | 0.0 | |||||||||||||
6qc4 | 1 | ? | 91.48 | 0.0 |
EM |
2019-08-21 | PHE | A:425 | a1:425 | 19.0 | 0.09 | E | -146.3 | 115.8 | 19.0 | 0.09 | 0.0 | ||||||
PHE | K:425 | a3:425 | 21.0 | 0.1 | E | -141.6 | 127.3 | 21.0 | 0.1 | 0.0 | |||||||||||||
5j4z | 51 | W5Q5G6 | 90.87 | 0.0 |
EM |
2016-09-21 | PHE | CB:428 | AA:425 | 34.0 | NA | -134.4 | 127.4 | 16.0 | NA | NA |
KB:W5P2X9:NA |
||||||
PHE | NB:428 | AL:425 | 34.0 | NA | -134.3 | 127.4 | 16.0 | NA | NA |
VB:W5P2X9:NA |
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1be3 | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
1999-01-13 | PHE | A:425 | A:425 | 22.0 | 0.105 | E | -137.6 | 118.8 | 22.0 | 0.105 | 0.0 | ||||||
1bgy | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
1999-01-06 | PHE | A:425 | A:425 | 22.0 | 0.105 | -150.8 | 59.4 | 22.0 | 0.105 | 0.0 | |||||||
PHE | L:425 | M:425 | 23.0 | 0.11 | E | -133.0 | 82.5 | 23.0 | 0.11 | 0.0 | |||||||||||||
1l0l | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2003-04-08 | PHE | A:425 | A:425 | 17.0 | 0.081 | E | -140.0 | 131.7 | 17.0 | 0.081 | 0.0 | ||||||
1l0n | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2003-04-08 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -155.2 | 147.2 | 16.0 | 0.076 | 0.0 | ||||||
1ntk | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2003-10-07 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -161.4 | 138.8 | 16.0 | 0.076 | 0.0 |
HOH |
3.799 |
CE1 |
O |
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1ntm | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2003-10-07 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -144.2 | 142.9 | 16.0 | 0.076 | 0.0 |
HOH |
3.977 |
CE1 |
O |
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1ntz | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2003-10-07 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -150.8 | 143.7 | 16.0 | 0.076 | 0.0 |
HOH |
8.477 |
O |
O |
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1nu1 | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2003-10-07 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -144.7 | 148.7 | 16.0 | 0.076 | 0.0 | ||||||
1pp9 | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2004-07-20 | PHE | A:425 | A:425 | 17.0 | 0.081 | E | -153.5 | 130.5 | 17.0 | 0.081 | 0.0 |
HOH |
4.049 |
CZ |
O |
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PHE | K:425 | N:425 | 18.0 | 0.086 | E | -153.9 | 132.9 | 18.0 | 0.086 | 0.0 |
HOH |
5.213 |
CE1 |
O |
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1ppj | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2004-07-20 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -147.2 | 128.6 | 16.0 | 0.076 | 0.0 |
HOH |
4.323 |
CE2 |
O |
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PHE | K:425 | N:425 | 16.0 | 0.076 | E | -147.8 | 128.8 | 16.0 | 0.076 | 0.0 |
HOH |
5.214 |
CE1 |
O |
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1sqq | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2005-10-25 | PHE | A:425 | A:425 | 14.0 | 0.067 | E | -163.1 | 132.0 | 14.0 | 0.067 | 0.0 |
HOH |
5.240 |
CE2 |
O |
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1sqv | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2005-09-06 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -148.5 | 141.6 | 16.0 | 0.076 | 0.0 |
HOH |
5.377 |
CE1 |
O |
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1sqx | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2005-09-06 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -136.5 | 133.8 | 16.0 | 0.076 | 0.0 |
HOH |
5.240 |
CE1 |
O |
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2a06 | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2005-06-21 | PHE | A:425 | A:425 | 19.0 | 0.09 | E | -147.3 | 130.7 | 19.0 | 0.09 | 0.0 |
UNL HOH |
7.511 4.495 |
CZ CZ |
O1 O |
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PHE | K:425 | N:425 | 16.0 | 0.076 | E | -143.9 | 129.9 | 16.0 | 0.076 | 0.0 |
HOH |
5.187 |
CE1 |
O |
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2fyu | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2006-08-29 | PHE | A:425 | A:425 | 17.0 | 0.081 | E | -134.2 | 123.7 | 17.0 | 0.081 | 0.0 |
HOH |
5.111 |
CE2 |
O |
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2ybb | 9 | P31800 | 90.36 | 0.0 |
EM |
2011-10-19 | PHE | I:425 | A:425 | 18.0 | 0.086 | E | -153.5 | 130.5 | 18.0 | 0.086 | 0.0 |
HOH |
4.048 |
CZ |
O |
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PHE | HA:425 | a:425 | 16.0 | 0.076 | E | -153.8 | 132.9 | 16.0 | 0.076 | 0.0 |
HOH |
5.213 |
CE1 |
O |
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5gpn | 1 | P31800 | 90.36 | 0.0 |
EM |
2017-04-05 | PHE | A:425 | A:425 | 27.0 | NA | -150.8 | 59.3 | 27.0 | NA | NA | |||||||
PHE | M:425 | M:425 | 24.0 | NA | E | -133.0 | 82.5 | 24.0 | NA | NA | |||||||||||||
5klv | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2016-10-12 | PHE | A:425 | A:425 | 16.0 | 0.076 | E | -154.7 | 134.8 | 16.0 | 0.076 | 0.0 |
HOH |
3.417 |
HZ |
O |
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5luf | 1 | P31800 | 90.36 | 0.0 |
EM |
2016-11-30 | PHE | A:425 | c:425 | 21.0 | 0.1 | -150.8 | 59.3 | 21.0 | 0.1 | 0.0 | |||||||
PHE | L:425 | l:425 | 25.0 | 0.119 | E | -133.0 | 82.5 | 25.0 | 0.119 | 0.0 | |||||||||||||
6nhg | 1 | P31800 | 90.36 | 0.0 |
X-RAY |
2019-06-19 | PHE | A:425 | A:425 | 17.0 | 0.081 | E | -161.7 | 132.4 | 17.0 | 0.081 | 0.0 |
HOH |
4.567 |
HE1 |
O |
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6xvf | 1 | P31800 | 90.34 | 0.0 |
X-RAY |
2020-07-22 | PHE | A:424 | A:425 | 14.0 | 0.067 | E | -145.0 | 137.3 | 14.0 | 0.067 | 0.0 | ||||||
5nmi | 1 | P31800 | 90.32 | 0.0 |
X-RAY |
2017-06-14 | PHE | A:424 | A:425 | 13.0 | 0.062 | E | -134.3 | 129.3 | 13.0 | 0.062 | 0.0 | ||||||
PHE | L:424 | N:425 | 13.0 | 0.062 | E | -134.6 | 129.4 | 13.0 | 0.062 | 0.0 | |||||||||||||
6zft | 1 | P31800 | 90.09 | 0.0 |
X-RAY |
2021-06-30 | PHE | A:423 | A:425 | 17.0 | 0.081 | E | -143.9 | 141.3 | 17.0 | 0.081 | 0.0 | ||||||
6zfs | 1 | P31800 | 89.86 | 0.0 |
X-RAY |
2021-06-30 | PHE | A:424 | A:425 | 15.0 | 0.071 | E | -141.5 | 137.2 | 15.0 | 0.071 | 0.0 |
HOH |
5.393 |
CE1 |
O |
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6zfu | 1 | P31800 | 89.86 | 0.0 |
X-RAY |
2021-06-30 | PHE | A:424 | A:425 | 14.0 | 0.067 | E | -141.0 | 136.4 | 14.0 | 0.067 | 0.0 |
HOH |
5.375 |
CE1 |
O |
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7o37 | 1 | Q9CZ13 | 89.46 | 0.0 |
EM |
2021-10-13 | TYR | A:425 | A:425 | 29.0 | 0.126 | E | -153.9 | 123.2 | 29.0 | 0.126 | 0.0 | ||||||
TYR | K:425 | L:425 | 29.0 | 0.126 | E | -150.8 | 126.7 | 29.0 | 0.126 | 0.0 | |||||||||||||
7o3c | 1 | Q9CZ13 | 89.46 | 0.0 |
EM |
2021-10-13 | TYR | A:425 | A:425 | 32.0 | 0.139 | E | -154.0 | 121.2 | 32.0 | 0.139 | 0.0 | ||||||
TYR | K:425 | L:425 | 28.0 | 0.122 | E | -148.5 | 130.7 | 28.0 | 0.122 | 0.0 | |||||||||||||
7o3e | 1 | Q9CZ13 | 89.46 | 0.0 |
EM |
2021-10-13 | TYR | A:425 | A:425 | 32.0 | 0.139 | E | -153.8 | 131.1 | 24.0 | 0.104 | 0.035 |
P:Q99KD6:0.035 |
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TYR | H:425 | L:425 | 22.0 | 0.096 | E | -154.5 | 121.1 | 22.0 | 0.096 | 0.0 | |||||||||||||
7o3h | 1 | Q9CZ13 | 89.46 | 0.0 |
EM |
2021-10-13 | TYR | A:425 | A:425 | 29.0 | 0.126 | E | -146.7 | 125.6 | 29.0 | 0.126 | 0.0 | ||||||
TYR | K:425 | L:425 | 26.0 | 0.113 | E | -147.9 | 129.4 | 26.0 | 0.113 | 0.0 | |||||||||||||
6haw | 1 | P31800 | 89.19 | 0.0 |
X-RAY |
2019-01-16 | PHE | A:418 | A:425 | 15.0 | 0.071 | E | -146.7 | 135.0 | 15.0 | 0.071 | 0.0 | ||||||
1bcc | 1 | P13272 | 87.22 | 0.0 |
X-RAY |
1998-08-19 | PRO | A:425 | A:425 | 6.0 | 0.041 | E | -105.6 | 155.4 | 6.0 | 0.041 | 0.0 | ||||||
2bcc | 1 | ? | 87.22 | 0.0 |
X-RAY |
1999-08-02 | PRO | A:425 | A:425 | 6.0 | 0.041 | E | -95.5 | 165.9 | 6.0 | 0.041 | 0.0 | ||||||
3bcc | 1 | P31800 | 87.22 | 0.0 |
X-RAY |
1998-08-19 | PRO | A:425 | A:425 | 5.0 | 0.034 | E | -105.6 | 153.6 | 5.0 | 0.034 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31930-f1 | 1 | P31930 | 100.0 | 0.0 | TYR | A:459 | A:459 | 26.0 | 0.113 | E | -135.6 | 143.1 |