Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 48638430 . T A CCDS2774.1:NM_003365.2:c.944gAc>gTc_NP_003356.2:p.315D>V Homo sapiens ubiquinol-cytochrome c reductase core protein I (UQCRC1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5xte 11 P31930 100.0 0.0 EM
 2017-08-30 ASP K:281 L:315 49.0 0.327 E -142.1 143.9 3.0 0.02 0.307 B:P47985:0.307
ASP V:281 Y:315 46.0 0.307 E -144.7 147.2 7.0 0.047 0.26 M:P47985:0.26
5xth 68 P31930 100.0 0.0 EM
 2017-09-13 ASP QB:281 AL:315 48.0 0.32 E -142.1 143.9 3.0 0.02 0.3 HB:P47985:0.3
ASP BC:281 AY:315 46.0 0.307 E -144.7 147.3 7.0 0.047 0.26 AC:P22695:0.007
SB:P47985:0.26
5xti 68 P31930 100.0 0.0 EM
 2017-09-13 ASP QB:281 AL:315 48.0 0.32 E -142.1 143.9 3.0 0.02 0.3 HB:P47985:0.3
ASP BC:281 AY:315 47.0 0.313 E -144.7 147.2 7.0 0.047 0.266 SB:P47985:0.267
1sqb 1 P31800 89.17 0.0 X-RAY
 2004-09-07 ASP A:315 A:281 51.0 0.34 E -162.3 139.4 0.0 0.0 0.34 I:P13272:0.34
 HOH
 5.579
 OD1
 O
1sqp 1 P31800 89.17 0.0 X-RAY
 2005-11-01 ASP A:315 A:281 56.0 0.373 E -159.1 135.7 0.0 0.0 0.373 I:P13272:0.373
 HOH
 5.253
 O
 O
4d6t 1 P31800 89.17 0.0 X-RAY
 2015-01-14 ASP A:315 A:281 56.0 0.373 E -147.9 161.8 39.0 0.26 0.113 I:P13272:0.113
ASP K:315 N:281 55.0 0.367 E -149.9 158.9 NA NA NA
4d6u 1 P31800 89.17 0.0 X-RAY
 2015-01-14 ASP A:315 A:281 57.0 0.38 E -150.9 156.7 37.0 0.247 0.133 I:P13272:0.133
6fo0 1 P31800 89.17 0.0 EM
 2018-02-28 ASP A:315 N:281 46.0 0.307 -150.3 87.2 28.0 0.187 0.12 I:None:0.12
ASP K:315 A:281 46.0 0.307 -150.3 87.2 26.0 0.173 0.134 S:None:0.133
6fo2 1 P31800 89.17 0.0 EM
 2018-02-28 ASP A:315 N:281 47.0 0.313 -150.7 89.3 27.0 0.18 0.133 I:P13272:0.133
ASP K:315 A:281 46.0 0.307 -150.7 89.4 27.0 0.18 0.127 S:P13272:0.127
6fo6 2 P31800 89.17 0.0 EM
 2018-02-28 ASP B:315 A:281 58.0 0.387 E -132.8 170.8 58.0 0.387 0.0
ASP K:315 N:281 57.0 0.38 E -132.8 170.8 57.0 0.38 0.0
4d6u 10 P31800 88.96 0.0 X-RAY
 2015-01-14 ASP K:315 N:281 57.0 0.38 E -151.8 156.2 NA NA NA
5okd 1 P31800 88.75 0.0 X-RAY
 2018-02-28 ASP A:315 A:281 49.0 0.327 E -150.9 176.3 0.0 0.0 0.327 I:P13272:0.327
 HOH
 6.042
 O
 O
5gup 45 F1SKM0 88.75 0.0 EM
 2017-03-29 ASP UA:315 u:315 58.0 0.387 -153.1 158.1 0.0 0.0 0.387 PB:F1RNZ1:0.387
ASP FB:315 5:315 32.0 0.213 E -157.6 157.1 0.0 0.0 0.213 OB:F1RNZ1:0.213
5j7y 51 W5Q5G6 91.48 0.0 EM
 2016-09-21 ASP CB:281 AA:281 57.0 NA -87.2 132.1 43.0 NA NA KB:W5P2X9:NA
ASP NB:281 AL:281 55.0 NA -87.3 132.2 42.0 NA NA VB:W5P2X9:NA
5j8k 51 W5Q5G6 91.48 0.0 EM
 2016-09-21 ASP CB:281 AA:281 57.0 NA -87.2 132.1 42.0 NA NA KB:W5P2X9:NA
ASP NB:281 AL:281 55.0 NA -87.4 132.2 42.0 NA NA VB:W5P2X9:NA
6q9e 1 W5Q5G6 91.48 0.0 EM
 2019-08-21 ASP A:281 a1:281 56.0 0.373 -134.8 162.2 44.0 0.293 0.08 B:W5Q0F9:0.02
I:None:0.06
ASP K:281 a3:281 55.0 0.367 -125.1 155.0 6.0 0.04 0.327 S:None:0.327
L:W5Q0F9:0.013
6qbx 1 W5Q5G6 91.48 0.0 EM
 2019-08-21 ASP A:281 a1:281 57.0 0.38 E -127.2 146.4 47.0 0.313 0.067 I:None:0.067
ASP K:281 a3:281 54.0 0.36 -125.5 153.9 47.0 0.313 0.047 S:None:0.027
L:W5Q0F9:0.02
6qc2 29 ? 91.48 0.0 EM
 2019-08-21 ASP CA:281 a1:281 60.0 0.4 -124.8 152.2 45.0 0.3 0.1 DA:W5Q0F9:0.02
KA:None:0.08
ASP MA:281 a3:281 51.0 0.34 E -133.7 150.0 6.0 0.04 0.3 UA:None:0.3
NA:W5Q0F9:0.013
6qc3 1 ? 91.48 0.0 EM
 2019-08-21 ASP A:281 a1:281 50.0 0.333 E -131.3 157.5 41.0 0.273 0.06 I:None:0.047
B:W5Q0F9:0.013
ASP K:281 a3:281 66.0 0.44 E -117.7 150.6 51.0 0.34 0.1 S:None:0.067
L:W5Q0F9:0.033
6qc4 1 ? 91.48 0.0 EM
 2019-08-21 ASP A:281 a1:281 57.0 0.38 E -124.3 146.5 46.0 0.307 0.073 I:None:0.067
B:W5Q0F9:0.007
ASP K:281 a3:281 54.0 0.36 E -124.5 155.3 5.0 0.033 0.327 S:None:0.32
L:W5Q0F9:0.013
5j4z 51 W5Q5G6 90.87 0.0 EM
 2016-09-21 ASP CB:284 AA:281 56.0 NA -87.2 132.1 42.0 NA NA KB:W5P2X9:NA
ASP NB:284 AL:281 57.0 NA -87.4 132.2 43.0 NA NA VB:W5P2X9:NA
1be3 1 P31800 90.36 0.0 X-RAY
 1999-01-13 ASP A:281 A:281 60.0 0.4 E -140.6 152.8 52.0 0.347 0.053 I:P13272:0.053
1bgy 1 P31800 90.36 0.0 X-RAY
 1999-01-06 ASP A:281 A:281 61.0 0.407 E -144.0 166.2 56.0 0.373 0.034 I:P13272:0.033
B:P23004:0.007
ASP L:281 M:281 63.0 0.42 E -142.3 149.8 58.0 0.387 0.033 T:P13272:0.033
1l0l 1 P31800 90.36 0.0 X-RAY
 2003-04-08 ASP A:281 A:281 54.0 0.36 E -151.3 143.6 0.0 0.0 0.36 I:P13272:0.36
1l0n 1 P31800 90.36 0.0 X-RAY
 2003-04-08 ASP A:281 A:281 50.0 0.333 E -158.7 151.9 0.0 0.0 0.333 I:P13272:0.333
1ntk 1 P31800 90.36 0.0 X-RAY
 2003-10-07 ASP A:281 A:281 51.0 0.34 E -161.2 149.7 0.0 0.0 0.34 I:P13272:0.34
 HOH
 5.417
 O
 O
1ntm 1 P31800 90.36 0.0 X-RAY
 2003-10-07 ASP A:281 A:281 52.0 0.347 E -152.9 147.1 0.0 0.0 0.347 I:P13272:0.347
 HOH
 5.618
 OD1
 O
1ntz 1 P31800 90.36 0.0 X-RAY
 2003-10-07 ASP A:281 A:281 49.0 0.327 E -157.3 147.2 0.0 0.0 0.327 I:P13272:0.327
 HOH
 5.071
 O
 O
1nu1 1 P31800 90.36 0.0 X-RAY
 2003-10-07 ASP A:281 A:281 50.0 0.333 E -166.9 153.2 0.0 0.0 0.333 I:P13272:0.333
1pp9 1 P31800 90.36 0.0 X-RAY
 2004-07-20 ASP A:281 A:281 50.0 0.333 E -159.0 153.6 0.0 0.0 0.333 I:P13272:0.333
 HOH
 2.982
 OD2
 O
ASP K:281 N:281 52.0 0.347 E -158.9 154.9 0.0 0.0 0.347 S:P13272:0.347
 HOH
 5.880
 O
 O
1ppj 1 P31800 90.36 0.0 X-RAY
 2004-07-20 ASP A:281 A:281 48.0 0.32 E -159.3 157.1 0.0 0.0 0.32 I:P13272:0.32
 HOH
 2.861
 OD2
 O
ASP K:281 N:281 49.0 0.327 E -158.3 157.6 0.0 0.0 0.327 S:P13272:0.327
 HOH
 3.258
 OD2
 O
1sqq 1 P31800 90.36 0.0 X-RAY
 2005-10-25 ASP A:281 A:281 54.0 0.36 E -168.7 147.5 0.0 0.0 0.36 I:P13272:0.36
 HOH
 4.345
 O
 O
1sqv 1 P31800 90.36 0.0 X-RAY
 2005-09-06 ASP A:281 A:281 51.0 0.34 E -163.3 144.6 0.0 0.0 0.34 I:P13272:0.34
 HOH
 5.637
 OD2
 O
1sqx 1 P31800 90.36 0.0 X-RAY
 2005-09-06 ASP A:281 A:281 50.0 0.333 E -139.7 179.2 0.0 0.0 0.333 G:P13272:0.333
 HOH
 5.583
 CB
 O
2a06 1 P31800 90.36 0.0 X-RAY
 2005-06-21 ASP A:281 A:281 49.0 0.327 E -151.8 156.8 0.0 0.0 0.327 I:P13272:0.327
 HOH
 2.959
 OD2
 O
ASP K:281 N:281 51.0 0.34 E -150.3 158.7 0.0 0.0 0.34 S:P13272:0.34
 UNL
HOH
 8.135
4.485
 O
O
 O1
O
2fyu 1 P31800 90.36 0.0 X-RAY
 2006-08-29 ASP A:281 A:281 54.0 0.36 E -151.1 149.7 0.0 0.0 0.36 I:P13272:0.36
 HOH
 4.838
 O
 O
2ybb 9 P31800 90.36 0.0 EM
 2011-10-19 ASP I:281 A:281 50.0 0.333 E -159.0 153.6 0.0 0.0 0.333 Q:P13272:0.333
 HOH
 2.981
 OD2
 O
ASP HA:281 a:281 51.0 0.34 E -159.0 154.8 0.0 0.0 0.34 PA:P13272:0.34
 HOH
 5.881
 O
 O
5gpn 1 P31800 90.36 0.0 EM
 2017-04-05 ASP A:281 A:281 56.0 NA E -144.0 166.1 54.0 NA NA I:P13272:NA
ASP M:281 M:281 55.0 NA E -142.3 149.7 55.0 NA NA
5klv 1 P31800 90.36 0.0 X-RAY
 2016-10-12 ASP A:281 A:281 45.0 0.3 E -150.8 172.7 30.0 0.2 0.1 I:P13272:0.1
 GOL
HOH
 7.054
7.874
 O
OD2
 HO1
O
5luf 1 P31800 90.36 0.0 EM
 2016-11-30 ASP A:281 c:281 62.0 0.413 E -144.1 166.2 56.0 0.373 0.04 B:P23004:0.007
I:P13272:0.033
ASP L:281 l:281 63.0 0.42 E -142.3 149.8 58.0 0.387 0.033 T:P13272:0.033
6nhg 1 P31800 90.36 0.0 X-RAY
 2019-06-19 ASP A:281 A:281 51.0 0.34 E -145.6 155.4 41.0 0.273 0.067 B:P23004:0.013
I:P13272:0.06
 HOH
 4.798
 OD2
 O
6xvf 1 P31800 90.34 0.0 X-RAY
 2020-07-22 ASP A:280 A:281 51.0 0.34 E -147.1 175.2 0.0 0.0 0.34 I:P13272:0.34
 HOH
 8.225
 O
 O
5nmi 1 P31800 90.32 0.0 X-RAY
 2017-06-14 ASP A:280 A:281 57.0 0.38 E -141.8 151.6 39.0 0.26 0.12 B:P23004:0.007
I:P13272:0.113
ASP L:280 N:281 56.0 0.373 E -141.7 151.6 40.0 0.267 0.106 T:P13272:0.107
6zft 1 P31800 90.09 0.0 X-RAY
 2021-06-30 ASP A:279 A:281 51.0 0.34 E -156.5 171.0 0.0 0.0 0.34 I:P13272:0.34
 HOH
 5.778
 O
 O
6zfs 1 P31800 89.86 0.0 X-RAY
 2021-06-30 ASP A:280 A:281 49.0 0.327 E -145.8 174.7 0.0 0.0 0.327 I:P13272:0.327
 HOH
 8.059
 O
 O
6zfu 1 P31800 89.86 0.0 X-RAY
 2021-06-30 ASP A:280 A:281 48.0 0.32 E -148.1 175.1 0.0 0.0 0.32 I:P13272:0.32
7o37 1 Q9CZ13 89.46 0.0 EM
 2021-10-13 ASP A:281 A:281 53.0 0.353 E -142.0 168.7 2.0 0.013 0.34 U:Q9CR68:0.34
ASP K:281 L:281 56.0 0.373 E -130.7 157.2 42.0 0.28 0.093 U:Q9CR68:0.087
L:Q9DB77:0.007
7o3c 1 Q9CZ13 89.46 0.0 EM
 2021-10-13 ASP A:281 A:281 49.0 0.327 E -137.9 175.9 3.0 0.02 0.307 U:Q9CR68:0.307
ASP K:281 L:281 54.0 0.36 E -132.2 161.4 42.0 0.28 0.08 U:Q9CR68:0.08
7o3e 1 Q9CZ13 89.46 0.0 EM
 2021-10-13 ASP A:281 A:281 56.0 0.373 E -133.7 158.5 4.0 0.027 0.346 O:Q9CR68:0.347
ASP H:281 L:281 56.0 0.373 E -130.5 165.1 40.0 0.267 0.106 I:Q9DB77:0.007
O:Q9CR68:0.107
7o3h 1 Q9CZ13 89.46 0.0 EM
 2021-10-13 ASP A:281 A:281 51.0 0.34 E -141.5 173.9 1.0 0.007 0.333 U:Q9CR68:0.333
ASP K:281 L:281 59.0 0.393 E -133.0 158.5 44.0 0.293 0.1 U:Q9CR68:0.087
L:Q9DB77:0.013
6haw 1 P31800 89.19 0.0 X-RAY
 2019-01-16 ASP A:274 A:281 50.0 0.333 E -144.4 174.9 1.0 0.007 0.326 I:P13272:0.327
 PO4
HOH
 7.301
5.765
 O
O
 O3
O
1bcc 1 P13272 87.22 0.0 X-RAY
 1998-08-19 ASP A:281 A:281 61.0 0.407 E 179.1 108.9 0.0 0.0 0.407 I:None:0.407
2bcc 1 ? 87.22 0.0 X-RAY
 1999-08-02 ASP A:281 A:281 60.0 0.4 E -158.0 135.8 0.0 0.0 0.4 I:None:0.4
B:None:0.007
3bcc 1 P31800 87.22 0.0 X-RAY
 1998-08-19 ASP A:281 A:281 64.0 0.427 E 176.0 98.5 0.0 0.0 0.427 B:P23004:0.007
I:None:0.427

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31930-f1 1 P31930 100.0 0.0 ASP A:315 A:315 47.0 0.313 E -141.7 153.9