Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr3 | 122354757 | . | A | C | CCDS46893.1:NM_001113523.1:c.1847tAc>tCc_NP_001106995.1:p.616Y>S | Homo sapiens poly (ADP-ribose) polymerase family, member 15 (PARP15), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3blj | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2007-12-25 | TYR | A:159 | A:594 | 0.0 | 0.0 | E | -98.7 | 148.7 | 0.0 | 0.0 | 0.0 |
CL HOH |
7.497 5.776 |
O OH |
CL O |
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| TYR | B:159 | B:594 | 0.0 | 0.0 | E | -91.5 | 151.3 | NA | NA | NA | |||||||||||||
| 3gey | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2009-03-24 | TYR | A:159 | A:594 | 0.0 | 0.0 | E | -97.2 | 145.4 | 0.0 | 0.0 | 0.0 |
P34 HOH |
6.647 9.670 |
O CD1 |
OAD O |
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| TYR | B:159 | B:594 | 0.0 | 0.0 | E | -88.6 | 152.4 | NA | NA | NA | |||||||||||||
| TYR | C:159 | C:594 | 1.0 | 0.004 | E | -100.4 | 144.3 | NA | NA | NA | |||||||||||||
| TYR | D:159 | D:594 | 0.0 | 0.0 | E | -95.7 | 148.0 | NA | NA | NA | |||||||||||||
| 7osp | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2021-12-08 | TYR | A:159 | A:616 | 0.0 | 0.0 | E | -91.9 | 147.0 | 0.0 | 0.0 | 0.0 |
0Q6 MPD HOH |
7.024 6.841 5.918 |
O CE2 OH |
OAC O2 O |
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| TYR | B:159 | B:616 | 0.0 | 0.0 | E | -86.6 | 148.0 | 0.0 | 0.0 | 0.0 |
DMS HOH |
6.912 5.976 |
O OH |
O O |
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| 7oss | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2021-12-08 | TYR | A:159 | A:616 | 0.0 | 0.0 | E | -92.2 | 148.0 | 0.0 | 0.0 | 0.0 |
0SI HOH |
7.036 5.950 |
O OH |
O1 O |
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| TYR | B:159 | B:616 | 0.0 | 0.0 | E | -87.6 | 148.7 | 0.0 | 0.0 | 0.0 |
DMS HOH |
7.130 5.642 |
O CE2 |
O O |
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| 7osx | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2021-12-08 | TYR | A:159 | A:616 | 0.0 | 0.0 | E | -91.2 | 147.1 | 0.0 | 0.0 | 0.0 |
0UI HOH |
7.076 5.902 |
O OH |
O1 O |
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| TYR | B:159 | B:616 | 0.0 | 0.0 | E | -86.3 | 148.8 | 0.0 | 0.0 | 0.0 |
DMS HOH |
6.949 5.651 |
O CE2 |
O O |
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| 7otf | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2021-12-08 | TYR | A:159 | A:616 | 0.0 | 0.0 | E | -87.9 | 146.2 | 0.0 | 0.0 | 0.0 |
1H9 DMS HOH |
6.976 6.171 5.885 |
O CE2 OH |
OAN C2 O |
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| TYR | B:159 | B:616 | 0.0 | 0.0 | E | -86.9 | 148.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.966 |
OH |
O |
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| 7oth | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2021-12-08 | TYR | A:159 | A:616 | 0.0 | 0.0 | E | -89.2 | 147.6 | 0.0 | 0.0 | 0.0 |
VJN HOH |
7.063 5.822 |
O OH |
O2 O |
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| TYR | B:159 | B:616 | 0.0 | 0.0 | E | -83.9 | 145.6 | 0.0 | 0.0 | 0.0 |
DMS HOH |
6.810 5.620 |
O CE2 |
O O |
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| 7ouw | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2021-12-08 | TYR | A:159 | A:616 | 0.0 | 0.0 | E | -89.1 | 147.5 | 0.0 | 0.0 | 0.0 |
1OI HOH |
6.990 7.100 |
O OH |
O2 O |
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| TYR | B:159 | B:616 | 0.0 | 0.0 | E | -90.2 | 149.2 | 0.0 | 0.0 | 0.0 |
DMS HOH |
6.759 5.743 |
O CE2 |
O O |
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| 7oux | 1 | Q460N3 | 94.84 | 1e-147 |
X-RAY |
2021-12-08 | TYR | A:159 | A:616 | 0.0 | 0.0 | E | -93.1 | 144.9 | 0.0 | 0.0 | 0.0 |
1O7 HOH |
6.982 5.840 |
O OH |
O2 O |
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| TYR | B:159 | B:616 | 0.0 | 0.0 | E | -90.2 | 145.3 | 0.0 | 0.0 | 0.0 |
DMS HOH |
7.102 5.564 |
O CE2 |
O O |
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| 4f0e | 1 | Q460N3 | 99.0 | 2e-147 |
X-RAY |
2012-09-05 | TYR | A:138 | A:594 | 0.0 | 0.0 | E | -95.0 | 146.4 | 0.0 | 0.0 | 0.0 |
0RU HOH |
7.311 6.815 |
N CE2 |
OAB O |
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| TYR | B:138 | B:594 | 0.0 | 0.0 | E | -95.6 | 137.3 | NA | NA | NA | |||||||||||||
| TYR | C:138 | C:594 | 0.0 | 0.0 | E | -86.2 | 146.2 | NA | NA | NA | |||||||||||||
| TYR | D:138 | D:594 | 0.0 | 0.0 | E | -103.2 | 144.7 | NA | NA | NA | |||||||||||||
| 7oqq | 1 | Q460N3 | 100.0 | 3e-147 |
X-RAY |
2021-12-08 | TYR | A:136 | A:616 | 0.0 | 0.0 | E | -89.1 | 142.8 | 0.0 | 0.0 | 0.0 |
DMS G18 HOH |
6.625 7.088 5.721 |
CE2 O OH |
C1 OAB O |
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| TYR | B:136 | B:616 | 0.0 | 0.0 | E | -85.8 | 147.5 | 0.0 | 0.0 | 0.0 |
DMS HOH |
7.071 5.771 |
O OH |
O O |
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| 6ek3 | 1 | Q460N3 | 94.37 | 2e-146 |
X-RAY |
2018-07-25 | TYR | A:159 | A:421 | 0.0 | 0.0 | E | -90.8 | 150.7 | 0.0 | 0.0 | 0.0 |
OUL HOH |
7.064 5.887 |
O OH |
OAQ O |
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| TYR | B:159 | B:421 | 0.0 | 0.0 | E | -85.2 | 149.1 | 0.0 | 0.0 | 0.0 |
OUL HOH |
6.923 5.928 |
O CE2 |
OAC O |
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| 6ry4 | 1 | Q460N3 | 100.0 | 2e-146 |
X-RAY |
2020-07-15 | TYR | A:135 | A:616 | 0.0 | 0.0 | E | -91.3 | 144.8 | 0.0 | 0.0 | 0.0 |
KMW HOH |
7.157 5.773 |
O OH |
OAQ O |
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| TYR | B:135 | B:616 | 0.0 | 0.0 | E | -86.2 | 145.8 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q460n3-f1 | 1 | Q460N3 | 100.0 | 0.0 | TYR | A:616 | A:616 | 0.0 | 0.0 | E | -82.3 | 144.0 | |