Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 184082821 . T A CCDS3264.1:NM_006232.3:c.141atT>atA_NP_006223.2:p.47I>I Homo sapiens RNA polymerase II subunit H (POLR2H), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5flm 8 F2Z4H3 100.0 1e-78 EM
 2016-01-20 ILE H:47 H:47 124.0 0.709 T -67.3 -52.6 22.0 0.126 0.583 A:None:0.474
C:Q3T0Q3:0.114
5iy6 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 111.0 0.634 T -103.3 -11.3 40.0 0.229 0.405 C:P19387:0.034
A:P24928:0.371
5iy7 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 111.0 0.634 T -113.2 0.8 38.0 0.217 0.417 C:P19387:0.097
A:P24928:0.32
5iy8 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 115.0 0.657 T -108.4 -6.3 34.0 0.194 0.463 C:P19387:0.126
A:P24928:0.337
5iy9 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 114.0 0.651 T -107.1 10.3 37.0 0.211 0.44 C:P19387:0.091
A:P24928:0.349
5iya 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 111.0 0.634 T -103.2 -11.3 41.0 0.234 0.4 A:P24928:0.366
C:P19387:0.04
5iyb 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 111.0 0.634 T -113.1 0.8 38.0 0.217 0.417 A:P24928:0.326
C:P19387:0.086
5iyc 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 114.0 0.651 T -108.4 -6.4 35.0 0.2 0.451 A:P24928:0.331
C:P19387:0.12
5iyd 8 P52434 100.0 1e-78 EM
 2016-05-18 ILE H:47 H:47 113.0 0.646 T -107.1 10.3 35.0 0.2 0.446 A:P24928:0.354
C:P19387:0.091
5oik 8 F2Z4H3 100.0 1e-78 EM
 2017-09-13 ILE H:47 H:47 127.0 0.726 T -77.9 -22.8 22.0 0.126 0.6 A:None:0.486
C:Q3T0Q3:0.171
6drd 8 P52434 100.0 1e-78 EM
 2019-06-12 ILE H:47 H:47 125.0 0.714 T -67.5 -39.7 15.0 0.086 0.628 A:P24928:0.491
C:P19387:0.149
6exv 8 I3LCB2 100.0 1e-78 EM
 2018-03-21 ILE H:47 H:47 127.0 0.726 T -74.1 -52.6 14.0 0.08 0.646 A:I3LJR4:0.606
C:I3LCH3:0.12
6gmh 8 I3LCB2 100.0 1e-78 EM
 2018-08-22 ILE H:47 H:47 119.0 0.68 T -89.1 -14.3 18.0 0.103 0.577 C:I3LCH3:0.2
A:None:0.406
6gml 6 I3LCB2 100.0 1e-78 EM
 2018-09-05 ILE F:47 H:47 126.0 0.72 T -82.7 -11.7 14.0 0.08 0.64 C:I3LCH3:0.24
A:None:0.48
6o9l 8 P52434 100.0 1e-78 EM
 2019-05-29 ILE H:47 H:47 120.0 0.686 T -97.1 -3.0 37.0 0.211 0.475 C:P19387:0.074
A:P24928:0.406
6ted 8 I3LCB2 100.0 1e-78 EM
 2020-07-22 ILE H:47 H:47 114.0 0.651 T -96.9 -8.5 22.0 0.126 0.525 C:I3LCH3:0.131
A:A0A480RVL6:0.44
6xre 8 P52434 100.0 1e-78 EM
 2021-03-24 ILE H:47 H:47 116.0 0.663 T -99.7 -8.4 6.0 0.034 0.629 A:P24928:0.486
C:P19387:0.2
7a6h 8 P52434 100.0 1e-78 EM
 2021-02-03 ILE H:47 H:47 113.0 0.646 T -86.0 -13.1 2.0 0.011 0.635 A:O14802:0.389
C:O15160:0.331
7ae1 8 P52434 100.0 1e-78 EM
 2021-02-03 ILE H:47 H:47 113.0 0.646 T -67.7 -37.7 1.0 0.006 0.64 A:O14802:0.383
C:O15160:0.326
7ae3 8 P52434 100.0 1e-78 EM
 2021-02-03 ILE H:47 H:47 118.0 0.674 T -79.6 -14.5 1.0 0.006 0.668 A:O14802:0.406
C:O15160:0.36
7aea 8 P52434 100.0 1e-78 EM
 2021-02-03 ILE H:47 H:47 116.0 0.663 T -85.8 -13.4 2.0 0.011 0.652 A:O14802:0.4
C:O15160:0.337
7ast 5 P52434 100.0 1e-78 EM
 2020-12-23 ILE E:47 D:47 121.0 0.691 S -124.1 32.9 121.0 0.691 0.0
7b0y 8 I3LCB2 100.0 1e-78 EM
 2021-01-13 ILE H:47 H:47 121.0 0.691 T -97.4 -19.6 14.0 0.08 0.611 A:P11414:0.491
C:I3LCH3:0.217
7b7u 6 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-19 ILE F:47 H:47 108.0 0.617 T -93.4 -24.6 9.0 0.051 0.566 A:I3LJR4:0.434
C:I3LCH3:0.189
7d58 8 P52434 100.0 1e-78 EM
 2021-02-17 ILE H:47 H:47 128.0 0.731 T -84.3 -52.7 11.0 0.063 0.668 C:O15160:0.217
A:O14802:0.48
7d59 8 P52434 100.0 1e-78 EM
 2021-02-17 ILE H:47 H:47 126.0 0.72 T -84.9 -53.3 17.0 0.097 0.623 C:O15160:0.16
A:O14802:0.463
7dn3 11 P52434 100.0 1e-78 EM
 2021-03-17 ILE K:47 H:47 121.0 0.691 T -86.9 -33.4 11.0 0.063 0.628 A:O14802:0.469
C:O15160:0.217
7du2 10 P52434 100.0 1e-78 EM
 2021-03-17 ILE J:47 H:47 121.0 0.691 T -86.9 -33.4 11.0 0.063 0.628 A:O14802:0.463
C:O15160:0.211
7edx 28 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE HA:47 v:47 128.0 0.731 S -90.7 -47.4 33.0 0.189 0.542 DA:I3LCH3:0.12
BA:None:0.474
7eg7 28 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE HA:47 v:47 130.0 0.743 S -90.9 -47.4 39.0 0.223 0.52 DA:I3LCH3:0.126
BA:None:0.446
7eg8 29 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE IA:47 v:47 130.0 0.743 S -90.7 -47.6 33.0 0.189 0.554 BA:None:0.491
DA:I3LCH3:0.126
7eg9 30 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE JA:47 v:47 130.0 0.743 S -90.7 -47.5 24.0 0.137 0.606 DA:None:0.537
FA:I3LCH3:0.131
7ega 28 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE HA:47 v:47 131.0 0.749 S -90.6 -47.6 24.0 0.137 0.612 DA:A0A481DF93:0.137
BA:A0A480TA59:0.549
7egb 41 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE UA:47 v:47 129.0 0.737 S -90.6 -47.6 25.0 0.143 0.594 PA:I3LCH3:0.149
NA:P24928:0.52
7egc 41 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-12 ILE UA:47 v:47 129.0 0.737 S -90.6 -47.5 24.0 0.137 0.6 PA:I3LCH3:0.154
NA:P24928:0.52
7ena 17 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-26 ILE Q:47 PH:47 131.0 0.749 T -93.9 -16.2 27.0 0.154 0.595 L:I3LCH3:0.154
J:None:0.474
7enc 62 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-26 ILE PB:47 PH:47 116.0 0.663 T -68.3 -44.1 24.0 0.137 0.526 IB:None:0.457
KB:I3LCH3:0.143
7f4g 6 A0A4X1ULF2 100.0 1e-78 EM
 2021-07-07 ILE F:47 H:47 121.0 0.691 T -79.9 -25.2 15.0 0.086 0.605 A:None:0.509
C:I3LCH3:0.189
7fji 8 P52434 100.0 1e-78 EM
 2021-10-27 ILE H:47 H:47 114.0 0.651 T -67.5 -37.8 2.0 0.011 0.64 C:O15160:0.309
A:O14802:0.4
7fjj 8 P52434 100.0 1e-78 EM
 2021-10-27 ILE H:47 H:47 113.0 0.646 T -67.5 -37.7 3.0 0.017 0.629 A:O14802:0.406
C:O15160:0.309
7lbm 12 P52434 100.0 1e-78 EM
 2021-03-24 ILE L:47 H:47 118.0 0.674 T -76.8 -10.8 17.0 0.097 0.577 E:P24928:0.491
G:P19387:0.149
7nvr 18 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE R:47 H:47 119.0 0.68 T -95.4 -23.5 13.0 0.074 0.606 K:None:0.469
M:I3LCH3:0.2
7nvs 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE H:47 H:47 119.0 0.68 T -94.7 -23.5 17.0 0.097 0.583 C:I3LCH3:0.166
A:None:0.457
7nvt 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE H:47 H:47 118.0 0.674 T -96.8 -21.4 14.0 0.08 0.594 C:I3LCH3:0.183
A:None:0.469
7nvu 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE H:47 H:47 114.0 0.651 T -87.1 -23.3 14.0 0.08 0.571 A:None:0.44
C:I3LCH3:0.171
7nvy 16 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE P:47 H:47 120.0 0.686 T -94.8 -26.0 17.0 0.097 0.589 I:None:0.463
K:I3LCH3:0.171
7nvz 16 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE P:47 H:47 119.0 0.68 T -96.3 -23.7 15.0 0.086 0.594 I:None:0.469
K:I3LCH3:0.189
7nw0 16 A0A4X1ULF2 100.0 1e-78 EM
 2021-05-05 ILE P:47 H:47 110.0 0.629 T -88.3 -25.8 13.0 0.074 0.555 I:None:0.429
K:I3LCH3:0.166
7ob9 7 P52434 100.0 1e-78 EM
 2021-12-08 ILE G:47 H:47 119.0 0.68 T -80.9 -13.4 39.0 0.223 0.457 A:O95602:0.457
7oba 7 P52434 100.0 1e-78 EM
 2021-12-08 ILE G:47 H:47 129.0 0.737 T -85.6 -52.1 46.0 0.263 0.474 A:O95602:0.474
7obb 7 P52434 100.0 1e-78 EM
 2021-12-08 ILE G:47 H:47 120.0 0.686 T -99.4 -43.5 38.0 0.217 0.469 A:O95602:0.469
7okx 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-07-14 ILE H:47 H:47 118.0 0.674 T -83.7 -15.6 13.0 0.074 0.6 A:P11414:0.514
C:I3LCH3:0.189
7oky 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-07-14 ILE H:47 H:47 118.0 0.674 T -83.7 -15.7 13.0 0.074 0.6 A:P11414:0.509
C:I3LCH3:0.183
7ol0 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-07-14 ILE H:47 H:47 118.0 0.674 T -88.9 -13.7 15.0 0.086 0.588 A:None:0.434
C:I3LCH3:0.177
7oo3 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-06 ILE H:47 H:47 121.0 0.691 T -95.0 -24.1 14.0 0.08 0.611 A:P11414:0.497
C:I3LCH3:0.183
7oob 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-13 ILE H:47 H:47 120.0 0.686 T -95.0 -24.0 14.0 0.08 0.606 A:P11414:0.486
C:I3LCH3:0.189
7oop 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-06 ILE H:47 H:47 120.0 0.686 T -95.1 -24.1 14.0 0.08 0.606 C:I3LCH3:0.189
A:P11414:0.486
7opc 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-13 ILE H:47 H:47 120.0 0.686 T -94.9 -24.2 14.0 0.08 0.606 C:I3LCH3:0.177
A:P11414:0.491
7opd 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-06 ILE H:47 H:47 120.0 0.686 T -94.9 -24.2 14.0 0.08 0.606 C:I3LCH3:0.177
A:P11414:0.491
7ozn 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-06 ILE H:47 H:47 127.0 0.726 T -69.1 -38.7 10.0 0.057 0.669 A:None:0.429
C:A0A481DF93:0.297
ILE T:47 T:47 128.0 0.731 T -69.1 -38.8 9.0 0.051 0.68 M:None:0.434
O:A0A481DF93:0.297
7ozo 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-06 ILE H:47 H:47 129.0 0.737 T -69.2 -38.8 8.0 0.046 0.691 A:None:0.44
C:A0A481DF93:0.32
ILE T:47 T:47 127.0 0.726 T -69.2 -38.8 8.0 0.046 0.68 O:A0A481DF93:0.314
M:None:0.429
7ozp 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-10-06 ILE H:47 H:47 131.0 0.749 T -69.1 -38.8 7.0 0.04 0.709 A:None:0.451
C:A0A481DF93:0.343
ILE T:47 T:47 128.0 0.731 T -69.1 -38.8 8.0 0.046 0.685 M:None:0.44
O:A0A481DF93:0.337
7pks 8 A0A4X1ULF2 100.0 1e-78 EM
 2021-12-08 ILE H:47 H:47 122.0 0.697 T -96.6 -19.2 15.0 0.086 0.611 C:A0A481DF93:0.194
A:A0A7M4DUC2:0.463

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p52434-f1 1 P52434 100.0 5e-79 ILE A:47 A:47 120.0 0.686 T -90.8 -41.0