Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 20017108 . A C CCDS2633.1:NM_004162.4:c.179cAa>cCa_NP_004153.2:p.60Q>P Homo sapiens RAB5A, member RAS oncogene family (RAB5A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4q9u 2 P20339 99.42 2e-126 X-RAY
 2014-07-23 GLN B:47 B:60 82.0 0.456 -96.3 137.3 82.0 0.456 0.0
GLN F:47 F:60 98.0 0.544 -123.0 360.0 98.0 0.544 0.0
1tu3 1 P20339 100.0 3e-126 X-RAY
 2004-10-05 GLN A:47 A:60 51.0 0.283 E -151.8 121.1 47.0 0.261 0.022 F:Q15276:0.022
 HOH
 3.467
 OE1
 O
GLN B:47 B:60 50.0 0.278 E -167.8 123.1 50.0 0.278 0.0 HOH
 3.925
 NE2
 O
GLN C:47 C:60 48.0 0.267 -178.5 115.9 NA NA NA
GLN D:47 D:60 62.0 0.344 -169.0 95.9 NA NA NA
GLN E:47 E:60 49.0 0.272 E -141.0 138.7 NA NA NA
1tu4 1 P20339 100.0 3e-126 X-RAY
 2004-10-05 GLN A:47 A:60 17.0 0.094 E -151.6 133.8 17.0 0.094 0.0 HOH
 2.737
 OE1
 O
GLN B:47 B:60 45.0 0.25 E -128.1 118.1 NA NA NA
GLN C:47 C:60 13.0 0.072 E -145.6 132.6 NA NA NA
GLN D:47 D:60 24.0 0.133 E -142.0 118.4 NA NA NA
1n6h 1 P20339 100.0 3e-126 X-RAY
 2002-11-27 GLN A:46 A:60 56.0 0.311 E -152.9 143.3 56.0 0.311 0.0 HOH
 3.156
 OE1
 O
1r2q 1 P20339 100.0 3e-126 X-RAY
 2003-12-23 GLN A:46 A:60 57.0 0.317 E -132.8 148.4 57.0 0.317 0.0 HOH
 3.025
 C
 O
1n6p 1 P20339 99.41 2e-125 X-RAY
 2002-11-27 GLN A:46 A:60 62.0 0.344 E -155.5 147.9 62.0 0.344 0.0 HOH
 3.441
 NE2
 O
1n6o 1 P20339 99.41 2e-125 X-RAY
 2002-11-27 GLN A:46 A:60 60.0 0.333 E -153.7 146.3 60.0 0.333 0.0 HOH
 3.476
 N
 O
1n6r 1 P20339 99.41 2e-125 X-RAY
 2002-11-27 GLN A:46 A:60 58.0 0.322 E -152.4 145.1 58.0 0.322 0.0 HOH
 2.995
 OE1
 O
1n6n 1 P20339 99.41 3e-125 X-RAY
 2002-11-27 GLN A:46 A:60 58.0 0.322 E -150.4 143.5 58.0 0.322 0.0 HOH
 3.064
 OE1
 O
1n6i 1 P20339 99.41 4e-125 X-RAY
 2002-11-27 GLN A:46 A:60 60.0 0.333 E -151.0 144.1 60.0 0.333 0.0 HOH
 3.293
 OE1
 O
1n6k 1 P20339 99.41 4e-125 X-RAY
 2002-11-27 GLN A:46 A:60 56.0 0.311 E -152.4 143.8 56.0 0.311 0.0 HOH
 3.281
 OE1
 O
1n6l 1 P20339 99.41 4e-125 X-RAY
 2002-11-27 GLN A:46 A:60 57.0 0.317 E -153.7 142.5 57.0 0.317 0.0 HOH
 3.514
 N
 O
3mjh 1 P20339 99.4 2e-123 X-RAY
 2010-05-05 GLN A:45 A:60 61.0 0.339 E -159.6 159.7 61.0 0.339 0.0 HOH
 3.782
 NE2
 O
GLN C:45 C:60 60.0 0.333 E -148.4 163.9 NA NA NA
7bl1 6 P20339 98.21 2e-121 EM
 2021-03-03 GLN F:45 DDD:60 60.0 0.333 E -157.3 158.2 60.0 0.333 0.0
2hei 1 P61020 88.14 2e-119 X-RAY
 2006-07-04 GLN A:48 A:60 73.0 0.406 E -156.7 156.6 73.0 0.406 0.0 HOH
 3.628
 C
 O
GLN B:48 B:60 68.0 0.378 E -156.9 155.8 68.0 0.378 0.0 HOH
 3.709
 C
 O
4kyi 2 P51148 93.41 1e-116 X-RAY
 2014-08-13 GLN B:49 B:61 47.0 0.261 E -118.5 134.6 47.0 0.261 0.0
GLN D:49 D:61 56.0 0.311 E -128.8 140.1 NA NA NA
GLN F:49 F:61 57.0 0.317 E -125.9 149.2 NA NA NA
GLN H:49 H:61 57.0 0.317 E -148.4 135.1 NA NA NA
1huq 1 P35278 94.51 4e-116 X-RAY
 2001-02-07 GLN A:43 A:61 56.0 0.311 E -149.6 138.9 56.0 0.311 0.0 HOH
 3.071
 OE1
 O
1z0d 1 P35278 93.94 7e-116 X-RAY
 2005-07-26 GLN A:45 A:61 54.0 0.3 E -149.8 125.5 54.0 0.3 0.0 HOH
 2.616
 OE1
 O
GLN B:45 C:61 57.0 0.317 E -158.7 137.1 NA NA NA
1z07 1 P35278 93.9 8e-115 X-RAY
 2005-07-26 GLN A:45 A:61 65.0 0.361 E -142.1 146.7 65.0 0.361 0.0 HOH
 2.779
 NE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p20339-f1 1 P20339 100.0 3e-164 GLN A:60 A:60 55.0 0.306 E -141.0 139.5
af-p51148-f1 1 P51148 87.04 2e-140 GLN A:61 A:61 57.0 0.317 E -143.9 138.2
af-p61020-f1 1 P61020 81.86 1e-135 GLN A:60 A:60 60.0 0.333 E -146.9 140.6