Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 20025200 . C A CCDS2633.1:NM_004162.4:c.533gCt>gAt_NP_004153.2:p.178A>D Homo sapiens RAB5A, member RAS oncogene family (RAB5A), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4q9u 2 P20339 99.42 2e-126 X-RAY
 2014-07-23 ALA B:165 B:178 10.0 0.087 H -71.3 -24.2 10.0 0.087 0.0
ALA F:165 F:178 46.0 0.4 H -69.0 -48.4 46.0 0.4 0.0
1tu3 1 P20339 100.0 3e-126 X-RAY
 2004-10-05 ALA A:165 A:178 15.0 0.13 H -59.4 -34.0 15.0 0.13 0.0 HOH
 4.456
 O
 O
ALA B:165 B:178 9.0 0.078 H -60.7 -41.6 9.0 0.078 0.0 HOH
 3.613
 O
 O
ALA C:165 C:178 9.0 0.078 H -52.5 -38.1 NA NA NA
ALA D:165 D:178 63.0 0.548 H -65.5 -34.1 NA NA NA
ALA E:165 E:178 12.0 0.104 H -56.2 -34.5 NA NA NA
1tu4 1 P20339 100.0 3e-126 X-RAY
 2004-10-05 ALA A:165 A:178 10.0 0.087 H -50.5 -39.3 10.0 0.087 0.0 HOH
 2.866
 O
 O
ALA B:165 B:178 7.0 0.061 H -59.2 -23.1 NA NA NA
ALA C:165 C:178 16.0 0.139 H -55.0 -42.5 NA NA NA
ALA D:165 D:178 12.0 0.104 H -51.2 -38.8 NA NA NA
1n6h 1 P20339 100.0 3e-126 X-RAY
 2002-11-27 ALA A:164 A:178 9.0 0.078 H -56.8 -39.5 9.0 0.078 0.0 HOH
 4.848
 O
 O
1r2q 1 P20339 100.0 3e-126 X-RAY
 2003-12-23 ALA A:164 A:178 6.0 0.052 H -61.0 -35.6 6.0 0.052 0.0 HOH
 5.449
 O
 O
1n6p 1 P20339 99.41 2e-125 X-RAY
 2002-11-27 ALA A:164 A:178 4.0 0.035 H -55.7 -39.4 4.0 0.035 0.0 HOH
 2.930
 O
 O
1n6o 1 P20339 99.41 2e-125 X-RAY
 2002-11-27 ALA A:164 A:178 0.0 0.0 H -53.0 -43.1 0.0 0.0 0.0 HOH
 4.852
 O
 O
1n6r 1 P20339 99.41 2e-125 X-RAY
 2002-11-27 ALA A:164 A:178 6.0 0.052 H -53.5 -41.8 6.0 0.052 0.0 HOH
 4.719
 O
 O
1n6n 1 P20339 99.41 3e-125 X-RAY
 2002-11-27 ALA A:164 A:178 11.0 0.096 H -56.8 -38.2 11.0 0.096 0.0 HOH
 4.778
 O
 O
1n6i 1 P20339 99.41 4e-125 X-RAY
 2002-11-27 ALA A:164 A:178 9.0 0.078 H -57.7 -38.8 9.0 0.078 0.0 HOH
 2.983
 O
 O
1n6k 1 P20339 99.41 4e-125 X-RAY
 2002-11-27 ALA A:164 A:178 11.0 0.096 H -56.4 -39.1 11.0 0.096 0.0 HOH
 3.004
 O
 O
1n6l 1 P20339 99.41 4e-125 X-RAY
 2002-11-27 ALA A:164 A:178 8.0 0.07 H -58.3 -38.5 8.0 0.07 0.0 HOH
 4.170
 O
 O
3mjh 1 P20339 99.4 2e-123 X-RAY
 2010-05-05 ALA A:163 A:178 0.0 0.0 H -50.9 -36.9 0.0 0.0 0.0 HOH
 6.513
 O
 O
ALA C:163 C:178 0.0 0.0 H -57.5 -39.0 NA NA NA
7bl1 6 P20339 98.21 2e-121 EM
 2021-03-03 ALA F:163 DDD:178 0.0 0.0 H -53.3 -35.9 0.0 0.0 0.0
2hei 1 P61020 88.14 2e-119 X-RAY
 2006-07-04 ALA A:166 A:178 1.0 0.009 H -56.9 -40.4 1.0 0.009 0.0 HOH
 2.549
 O
 O
ALA B:166 B:178 1.0 0.009 H -53.1 -40.2 1.0 0.009 0.0 HOH
 2.577
 O
 O
4kyi 2 P51148 93.41 1e-116 X-RAY
 2014-08-13 ALA B:167 B:179 4.0 0.035 H -59.1 -31.9 4.0 0.035 0.0
ALA D:167 D:179 3.0 0.026 H -65.9 -34.5 NA NA NA
ALA F:167 F:179 6.0 0.052 H -57.7 -35.0 NA NA NA
ALA H:167 H:179 3.0 0.026 H -62.7 -31.7 NA NA NA
1huq 1 P35278 94.51 4e-116 X-RAY
 2001-02-07 ALA A:161 A:179 5.0 0.043 H -59.3 -40.8 5.0 0.043 0.0 HOH
 6.122
 N
 O
1z0d 1 P35278 93.94 7e-116 X-RAY
 2005-07-26 ALA A:163 A:179 4.0 0.035 H -56.5 -39.7 4.0 0.035 0.0 HOH
 2.638
 O
 O
ALA B:163 C:179 3.0 0.026 H -54.5 -41.8 NA NA NA
1z07 1 P35278 93.9 8e-115 X-RAY
 2005-07-26 ALA A:163 A:179 4.0 0.035 H -61.6 -34.4 4.0 0.035 0.0 HOH
 2.837
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p20339-f1 1 P20339 100.0 3e-164 ALA A:178 A:178 0.0 0.0 H -56.5 -36.3
af-p51148-f1 1 P51148 87.04 2e-140 ALA A:179 A:179 0.0 0.0 H -56.4 -37.3
af-p61020-f1 1 P61020 81.86 1e-135 ALA A:178 A:178 0.0 0.0 H -56.4 -38.8