Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3195649 . T A CCDS2562.1:NM_016302.3:c.946Aat>Tat_NP_057386.2:p.316N>Y Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:337 B:316 88.0 0.55 H -82.6 -41.9 86.0 0.537 0.013 A:Q16531:0.013
6bn8 2 Q96SW2 97.06 0.0 X-RAY
 2018-06-06 ASN B:337 B:316 95.0 0.594 H -75.3 -41.0 78.0 0.487 0.107 A:Q16531:0.106
6bn9 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:337 B:316 84.0 0.525 H -83.5 -35.2 72.0 0.45 0.075 A:Q16531:0.075
6bnb 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:337 B:316 109.0 0.681 T -103.6 5.9 75.0 0.469 0.212 A:Q16531:0.212
6boy 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:337 B:316 89.0 0.556 H -80.9 -41.4 81.0 0.506 0.05 A:Q16531:0.05
5hxb 3 Q96SW2 99.75 0.0 X-RAY
 2016-06-29 ASN C:280 Z:316 105.0 0.656 H -80.0 -47.6 105.0 0.656 0.0
ASN E:280 C:316 105.0 0.656 H -79.9 -47.5 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
 2017-05-03 ASN B:280 C:316 75.0 0.469 H -84.3 -51.8 67.0 0.419 0.05 A:Q16531:0.05
6uml 2 Q96SW2 99.75 0.0 X-RAY
 2020-04-15 ASN B:280 C:316 91.0 0.569 H -81.9 -43.7 87.0 0.544 0.025 A:Q16531:0.025
6xk9 3 Q96SW2 99.75 0.0 X-RAY
 2020-12-02 ASN C:280 Z:316 90.0 0.562 H -96.3 -42.5 83.0 0.519 0.043 B:Q16531:0.044
ASN F:280 C:316 92.0 0.575 H -96.2 -42.4 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
 2016-02-24 ASN B:300 B:316 81.0 0.506 H -96.0 -42.5 79.0 0.494 0.012 A:Q16531:0.013
 HOH
 3.651
 ND2
 O
ASN E:300 E:316 81.0 0.506 H -96.2 -41.3 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ASN B:300 B:316 87.0 0.544 H -66.4 -25.7 77.0 0.481 0.063 A:None:0.062
 HOH
 4.916
 HD21
 O
ASN E:300 E:316 87.0 0.544 H -66.3 -26.0 NA NA NA
ASN H:300 H:316 83.0 0.519 H -66.6 -25.9 NA NA NA
ASN K:300 K:316 84.0 0.525 H -66.8 -25.4 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ASN B:300 B:316 84.0 0.525 H -79.1 -47.5 76.0 0.475 0.05 A:Q16531:0.05
ASN E:300 E:316 79.0 0.494 H -93.1 -16.9 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
 2021-06-02 ASN B:270 B:316 82.0 0.512 H -84.1 -39.2 73.0 0.456 0.056 A:Q16531:0.056
ASN E:270 E:316 84.0 0.525 H -84.5 -37.9 NA NA NA
ASN H:270 H:316 83.0 0.519 H -84.3 -38.6 NA NA NA
ASN K:270 K:316 82.0 0.512 H -84.2 -38.6 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
 2014-08-06 ASN B:269 C:316 86.0 0.537 H -79.5 -48.8 75.0 0.469 0.068 A:Q16531:0.069
4ci1 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 ASN B:342 B:318 96.0 0.6 H -77.7 -48.6 96.0 0.6 0.0 HOH
 9.544
 ND2
 O
4ci2 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 ASN B:342 B:318 101.0 0.631 H -78.9 -42.7 101.0 0.631 0.0
4ci3 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 ASN B:342 B:318 97.0 0.606 H -78.1 -43.9 97.0 0.606 0.0
7bqu 1 Q96SW2 96.43 3e-76 X-RAY
 2020-08-26 GLY A:4 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 ASN A:316 A:316 70.0 0.438 H -77.2 -44.4