Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3195658 . C A CCDS2562.1:NM_016302.3:c.937Gac>Tac_NP_057386.2:p.313D>Y Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASP B:334 B:313 73.0 0.487 H -64.4 -38.7 68.0 0.453 0.034 A:Q16531:0.033
6bn8 2 Q96SW2 97.06 0.0 X-RAY
 2018-06-06 ASP B:334 B:313 67.0 0.447 H -63.9 -42.9 63.0 0.42 0.027 A:Q16531:0.027
6bn9 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASP B:334 B:313 72.0 0.48 H -59.6 -43.3 67.0 0.447 0.033 A:Q16531:0.033
6bnb 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASP B:334 B:313 89.0 0.593 H -60.0 -41.9 61.0 0.407 0.186 A:Q16531:0.187
6boy 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASP B:334 B:313 82.0 0.547 H -63.1 -38.8 74.0 0.493 0.054 A:Q16531:0.053
5hxb 3 Q96SW2 99.75 0.0 X-RAY
 2016-06-29 ASP C:277 Z:313 45.0 0.3 H -55.9 -55.6 45.0 0.3 0.0
ASP E:277 C:313 34.0 0.227 H -56.3 -55.5 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
 2017-05-03 ASP B:277 C:313 110.0 0.733 H -60.5 -56.4 107.0 0.713 0.02 A:Q16531:0.02
6uml 2 Q96SW2 99.75 0.0 X-RAY
 2020-04-15 ASP B:277 C:313 110.0 0.733 H -57.8 -52.6 110.0 0.733 0.0
6xk9 3 Q96SW2 99.75 0.0 X-RAY
 2020-12-02 ASP C:277 Z:313 65.0 0.433 H -68.9 -39.0 58.0 0.387 0.046 B:Q16531:0.047
ASP F:277 C:313 57.0 0.38 H -68.9 -38.8 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
 2016-02-24 ASP B:297 B:313 40.0 0.267 H -69.7 -39.7 27.0 0.18 0.087 A:Q16531:0.087
 HOH
 5.870
 N
 O
ASP E:297 E:313 41.0 0.273 H -69.4 -38.8 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ASP B:297 B:313 30.0 0.2 H -66.2 -48.4 29.0 0.193 0.007 A:None:0.007
 HOH
 5.398
 H
 O
ASP E:297 E:313 31.0 0.207 H -65.5 -48.5 NA NA NA
ASP H:297 H:313 31.0 0.207 H -65.8 -48.6 NA NA NA
ASP K:297 K:313 31.0 0.207 H -65.8 -48.5 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ASP B:297 B:313 27.0 0.18 H -59.5 -47.0 18.0 0.12 0.06 A:Q16531:0.06
ASP E:297 E:313 9.0 0.06 H -59.1 -47.7 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
 2021-06-02 ASP B:267 B:313 42.0 0.28 H -63.4 -43.7 21.0 0.14 0.14 A:Q16531:0.14
ASP E:267 E:313 41.0 0.273 H -63.8 -42.9 NA NA NA
ASP H:267 H:313 41.0 0.273 H -64.1 -42.7 NA NA NA
ASP K:267 K:313 42.0 0.28 H -64.2 -42.5 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
 2014-08-06 ASP B:266 C:313 107.0 0.713 H -55.6 -56.1 101.0 0.673 0.04 A:Q16531:0.04
4ci1 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 ASP B:339 B:315 67.0 0.447 H -64.2 -45.2 52.0 0.347 0.1 A:Q16531:0.1
 HOH
 5.191
 CG
 O
4ci2 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 ASP B:339 B:315 83.0 0.553 H -57.2 -48.7 63.0 0.42 0.133 A:Q16531:0.133
4ci3 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 ASP B:339 B:315 84.0 0.56 H -67.2 -46.7 59.0 0.393 0.167 A:Q16531:0.167

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 ASP A:313 A:313 42.0 0.28 H -63.7 -45.2