Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3195693 . A C CCDS2562.1:NM_016302.3:c.902aTt>aGt_NP_057386.2:p.301I>S Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ILE B:322 B:301 32.0 0.183 -68.8 131.4 32.0 0.183 0.0
6bn8 2 Q96SW2 97.06 0.0 X-RAY
2018-06-06 ILE B:322 B:301 34.0 0.194 -67.3 126.2 34.0 0.194 0.0
6bn9 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ILE B:322 B:301 28.0 0.16 -66.7 128.8 28.0 0.16 0.0
6bnb 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ILE B:322 B:301 10.0 0.057 -76.5 127.2 10.0 0.057 0.0
6boy 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ILE B:322 B:301 34.0 0.194 -69.1 131.7 34.0 0.194 0.0
5hxb 3 Q96SW2 99.75 0.0 X-RAY
2016-06-29 ILE C:265 Z:301 36.0 0.206 -73.9 130.4 32.0 0.183 0.023 B:Q16531:0.023
ILE E:265 C:301 22.0 0.126 -73.5 130.3 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
2017-05-03 ILE B:265 C:301 43.0 0.246 -51.7 113.9 43.0 0.246 0.0
6uml 2 Q96SW2 99.75 0.0 X-RAY
2020-04-15 ILE B:265 C:301 32.0 0.183 -72.5 129.6 32.0 0.183 0.0
6xk9 3 Q96SW2 99.75 0.0 X-RAY
2020-12-02 ILE C:265 Z:301 26.0 0.149 -71.9 126.0 26.0 0.149 0.0
ILE F:265 C:301 30.0 0.171 -71.5 126.1 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
2016-02-24 ILE B:285 B:301 15.0 0.086 -71.7 125.2 15.0 0.086 0.0 HOH
2.691
O
O
ILE E:285 E:301 17.0 0.097 -72.3 126.7 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
2018-11-07 ILE B:285 B:301 13.0 0.074 -68.4 130.1 13.0 0.074 0.0
ILE E:285 E:301 15.0 0.086 -68.0 130.1 NA NA NA
ILE H:285 H:301 11.0 0.063 -68.2 129.7 NA NA NA
ILE K:285 K:301 17.0 0.097 -68.4 130.2 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
2018-11-07 ILE B:285 B:301 24.0 0.137 -59.8 136.9 24.0 0.137 0.0
ILE E:285 E:301 26.0 0.149 -58.5 137.0 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
2021-06-02 ILE B:255 B:301 17.0 0.097 -57.4 132.1 17.0 0.097 0.0
ILE E:255 E:301 17.0 0.097 -57.7 132.4 NA NA NA
ILE H:255 H:301 17.0 0.097 -57.4 131.7 NA NA NA
ILE K:255 K:301 18.0 0.103 -57.4 132.0 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
2014-08-06 ILE B:254 C:301 32.0 0.183 -72.1 130.4 32.0 0.183 0.0
4ci1 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ILE B:327 B:303 25.0 0.143 -47.4 125.5 25.0 0.143 0.0 HOH
8.723
CG2
O
4ci2 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ILE B:327 B:303 35.0 0.2 -50.1 124.9 33.0 0.189 0.011 A:Q16531:0.011
HOH
8.890
CG2
O
4ci3 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ILE B:327 B:303 35.0 0.2 -46.4 126.5 35.0 0.2 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 ILE A:301 A:301 27.0 0.154 -67.5 122.1