Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3196475 . C A CCDS2562.1:NM_016302.3:c.791tGg>tTg_NP_057386.2:p.264W>L Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 TRP B:285 B:264 13.0 0.051 T -105.1 -44.5 13.0 0.051 0.0
6bn8 2 Q96SW2 97.06 0.0 X-RAY
 2018-06-06 TRP B:285 B:264 10.0 0.039 T -83.3 -67.6 10.0 0.039 0.0
6bn9 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 TRP B:285 B:264 7.0 0.027 T -87.7 -65.6 7.0 0.027 0.0
6bnb 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 TRP B:285 B:264 69.0 0.271 T -136.3 -33.3 69.0 0.271 0.0
6boy 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 TRP B:285 B:264 11.0 0.043 T -95.8 -56.9 11.0 0.043 0.0
5hxb 3 Q96SW2 99.75 0.0 X-RAY
 2016-06-29 TRP C:228 Z:264 16.0 0.063 S -61.4 -28.8 16.0 0.063 0.0
TRP E:228 C:264 23.0 0.09 T -100.9 -2.4 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
 2017-05-03 TRP B:228 C:264 15.0 0.059 H -77.6 -37.9 15.0 0.059 0.0
6uml 2 Q96SW2 99.75 0.0 X-RAY
 2020-04-15 TRP B:228 C:264 81.0 0.318 T -125.8 74.7 81.0 0.318 0.0
6xk9 3 Q96SW2 99.75 0.0 X-RAY
 2020-12-02 TRP C:228 Z:264 24.0 0.094 T -99.4 -33.7 24.0 0.094 0.0
TRP F:228 C:264 19.0 0.075 T -97.1 -34.5 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
 2016-02-24 TRP B:248 B:264 15.0 0.059 T -99.0 -33.2 15.0 0.059 0.0 HOH
 6.910
 C
 O
TRP E:248 E:264 16.0 0.063 T -99.7 -33.3 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 TRP B:248 B:264 56.0 0.22 H -68.7 -47.2 56.0 0.22 0.0
TRP E:248 E:264 46.0 0.18 H -69.4 -47.0 NA NA NA
TRP H:248 H:264 46.0 0.18 H -69.2 -47.0 NA NA NA
TRP K:248 K:264 57.0 0.224 H -69.6 -46.9 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 TRP B:248 B:264 19.0 0.075 T -90.5 -31.9 19.0 0.075 0.0
TRP E:248 E:264 16.0 0.063 T -91.6 -31.5 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
 2021-06-02 TRP B:218 B:264 14.0 0.055 T -94.6 -32.8 14.0 0.055 0.0
TRP E:218 E:264 14.0 0.055 T -95.0 -32.7 NA NA NA
TRP H:218 H:264 14.0 0.055 T -94.7 -33.0 NA NA NA
TRP K:218 K:264 14.0 0.055 T -94.7 -33.0 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
 2014-08-06 TRP B:217 C:264 17.0 0.067 T -99.9 -2.7 17.0 0.067 0.0
4ci1 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 TRP B:290 B:266 4.0 0.016 H -92.5 -44.1 4.0 0.016 0.0 HOH
 2.935
 NE1
 O
4ci2 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 TRP B:290 B:266 7.0 0.027 H -103.6 -37.2 7.0 0.027 0.0 HOH
 8.138
 O
 O
4ci3 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 TRP B:290 B:266 10.0 0.039 H -92.7 -43.1 10.0 0.039 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 TRP A:264 A:264 22.0 0.086 H -82.1 -41.2