Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3197929 . G A CCDS2562.1:NM_016302.3:c.724Cgc>Tgc_NP_057386.2:p.242R>C Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ARG B:263 B:242 88.0 0.391 H -68.6 -45.2 55.0 0.244 0.147 A:Q16531:0.147
6bn8 2 Q96SW2 97.06 0.0 X-RAY
 2018-06-06 ARG B:263 B:242 88.0 0.391 H -76.6 -42.3 58.0 0.258 0.133 A:Q16531:0.133
6bn9 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ARG B:263 B:242 96.0 0.427 H -75.6 -41.4 57.0 0.253 0.174 A:Q16531:0.173
6bnb 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ARG B:263 B:242 91.0 0.404 H -44.2 -63.2 47.0 0.209 0.195 A:Q16531:0.196
6boy 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ARG B:263 B:242 90.0 0.4 H -77.2 -43.0 61.0 0.271 0.129 A:Q16531:0.129
5hxb 3 Q96SW2 99.75 0.0 X-RAY
 2016-06-29 ARG C:206 Z:242 111.0 0.493 H -51.0 -46.1 88.0 0.391 0.102 B:Q16531:0.102
ARG E:206 C:242 113.0 0.502 H -50.5 -46.4 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
 2017-05-03 ARG B:206 C:242 97.0 0.431 H -64.0 -39.0 62.0 0.276 0.155 A:Q16531:0.156
6uml 2 Q96SW2 99.75 0.0 X-RAY
 2020-04-15 ARG B:206 C:242 97.0 0.431 H -52.3 -44.2 61.0 0.271 0.16 A:Q16531:0.16
6xk9 3 Q96SW2 99.75 0.0 X-RAY
 2020-12-02 ARG C:206 Z:242 111.0 0.493 H -55.8 -43.2 89.0 0.396 0.097 B:Q16531:0.098
ARG F:206 C:242 105.0 0.467 H -55.7 -43.1 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
 2016-02-24 ARG B:226 B:242 80.0 0.356 H -55.5 -42.7 53.0 0.236 0.12 A:Q16531:0.12
 HOH
 3.746
 N
 O
ARG E:226 E:242 80.0 0.356 H -56.0 -43.4 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ARG B:226 B:242 88.0 0.391 H -57.6 -48.4 62.0 0.276 0.115 A:None:0.116
ARG E:226 E:242 88.0 0.391 H -57.5 -48.5 NA NA NA
ARG H:226 H:242 89.0 0.396 H -57.5 -48.4 NA NA NA
ARG K:226 K:242 88.0 0.391 H -57.7 -48.3 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ARG B:226 B:242 88.0 0.391 H -64.8 -48.8 52.0 0.231 0.16 A:Q16531:0.16
ARG E:226 E:242 83.0 0.369 H -64.5 -49.0 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
 2021-06-02 ARG B:196 B:242 96.0 0.427 H -57.9 -50.3 66.0 0.293 0.134 A:Q16531:0.133
ARG E:196 E:242 84.0 0.373 H -57.9 -50.5 NA NA NA
ARG H:196 H:242 93.0 0.413 H -57.5 -50.2 NA NA NA
ARG K:196 K:242 97.0 0.431 H -57.2 -50.3 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
 2014-08-06 ARG B:195 C:242 100.0 0.444 H -50.1 -45.9 66.0 0.293 0.151 A:Q16531:0.151
 HOH
 9.282
 C
 O
4ci1 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 PRO B:268 B:244 45.0 0.31 H -60.5 -34.5 35.0 0.241 0.069 A:Q16531:0.069
4ci2 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 PRO B:268 B:244 42.0 0.29 H -55.8 -30.7 36.0 0.248 0.042 A:Q16531:0.041
4ci3 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 PRO B:268 B:244 44.0 0.303 H -61.3 -34.0 34.0 0.234 0.069 A:Q16531:0.069

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 ARG A:242 A:242 74.0 0.329 H -52.8 -39.5