Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3209397 . T A CCDS2562.1:NM_016302.3:c.608aAt>aTt_NP_057386.2:p.203N>I Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:224 B:203 89.0 0.556 G -59.6 -30.0 26.0 0.163 0.393 A:Q16531:0.394
6bn8 2 Q96SW2 97.06 0.0 X-RAY
 2018-06-06 ASN B:224 B:203 86.0 0.537 G -58.5 -24.6 24.0 0.15 0.387 A:Q16531:0.388
6bn9 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:224 B:203 88.0 0.55 G -56.6 -29.1 29.0 0.181 0.369 A:Q16531:0.369
6bnb 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:224 B:203 79.0 0.494 G -58.3 -38.5 24.0 0.15 0.344 A:Q16531:0.344
6boy 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 ASN B:224 B:203 90.0 0.562 G -58.0 -30.0 26.0 0.163 0.399 A:Q16531:0.4
5hxb 3 Q96SW2 99.75 0.0 X-RAY
 2016-06-29 ASN C:167 Z:203 63.0 0.394 G -49.6 -42.9 13.0 0.081 0.313 B:Q16531:0.312
ASN E:167 C:203 62.0 0.388 G -49.5 -42.5 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
 2017-05-03 ASN B:167 C:203 88.0 0.55 G -58.3 -45.3 31.0 0.194 0.356 A:Q16531:0.356
6uml 2 Q96SW2 99.75 0.0 X-RAY
 2020-04-15 ASN B:167 C:203 87.0 0.544 H -50.7 -42.2 30.0 0.188 0.356 A:Q16531:0.356
6xk9 3 Q96SW2 99.75 0.0 X-RAY
 2020-12-02 ASN C:167 Z:203 67.0 0.419 G -63.7 -38.6 11.0 0.069 0.35 B:Q16531:0.35
ASN F:167 C:203 72.0 0.45 G -63.9 -38.8 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
 2016-02-24 ASN B:187 B:203 90.0 0.562 G -63.8 -39.3 24.0 0.15 0.412 A:Q16531:0.412
 HOH
 8.362
 OD1
 O
ASN E:187 E:203 85.0 0.531 G -64.0 -39.4 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ASN B:187 B:203 68.0 0.425 H -58.7 -41.0 26.0 0.163 0.262 A:None:0.263
 HOH
 3.051
 HD21
 O
ASN E:187 E:203 71.0 0.444 H -58.7 -37.5 NA NA NA
ASN H:187 H:203 59.0 0.369 H -58.6 -40.5 NA NA NA
ASN K:187 K:203 84.0 0.525 H -58.2 -42.3 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 ASN B:187 B:203 87.0 0.544 S -53.7 -38.9 28.0 0.175 0.369 A:Q16531:0.369
ASN E:187 E:203 90.0 0.562 G -54.0 -37.1 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
 2021-06-02 ASN B:157 B:203 86.0 0.537 G -57.7 -36.8 26.0 0.163 0.374 A:Q16531:0.375
ASN E:157 E:203 88.0 0.55 G -57.8 -36.5 NA NA NA
ASN H:157 H:203 87.0 0.544 G -58.2 -36.9 NA NA NA
ASN K:157 K:203 88.0 0.55 G -58.2 -36.9 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
 2014-08-06 ASN B:156 C:203 86.0 0.537 G -47.4 -43.7 28.0 0.175 0.362 A:Q16531:0.362
 HOH
 8.087
 OD1
 O
4ci1 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 SER B:228 B:204 64.0 0.557 G -51.5 -45.6 20.0 0.174 0.383 A:Q16531:0.383
4ci2 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 SER B:228 B:204 59.0 0.513 -60.0 -43.1 18.0 0.157 0.356 A:Q16531:0.357
4ci3 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 SER B:228 B:204 65.0 0.565 G -51.2 -50.6 23.0 0.2 0.365 A:Q16531:0.365

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 ASN A:203 A:203 83.0 0.519 G -56.8 -40.1