Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3209416 . C A CCDS2562.1:NM_016302.3:c.589Gtt>Ttt_NP_057386.2:p.197V>F Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 VAL B:218 B:197 49.0 0.316 G -125.4 30.4 4.0 0.026 0.29 A:Q16531:0.29
6bn8 2 Q96SW2 97.06 0.0 X-RAY
 2018-06-06 VAL B:218 B:197 43.0 0.277 T -75.0 -19.7 3.0 0.019 0.258 A:Q16531:0.258
6bn9 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 VAL B:218 B:197 51.0 0.329 T -117.2 11.7 3.0 0.019 0.31 A:Q16531:0.31
6bnb 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 VAL B:218 B:197 53.0 0.342 T -124.1 -5.4 9.0 0.058 0.284 A:Q16531:0.284
6boy 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 VAL B:218 B:197 42.0 0.271 T -117.0 10.1 5.0 0.032 0.239 A:Q16531:0.239
5hxb 3 Q96SW2 99.75 0.0 X-RAY
 2016-06-29 VAL C:161 Z:197 53.0 0.342 T -114.1 -2.0 11.0 0.071 0.271 B:Q16531:0.271
VAL E:161 C:197 54.0 0.348 T -114.0 -2.6 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
 2017-05-03 VAL B:161 C:197 49.0 0.316 H -69.0 -31.8 4.0 0.026 0.29 A:Q16531:0.29
6uml 2 Q96SW2 99.75 0.0 X-RAY
 2020-04-15 VAL B:161 C:197 46.0 0.297 T -113.3 3.0 4.0 0.026 0.271 A:Q16531:0.271
6xk9 3 Q96SW2 99.75 0.0 X-RAY
 2020-12-02 VAL C:161 Z:197 36.0 0.232 G -136.7 31.5 7.0 0.045 0.187 B:Q16531:0.187
VAL F:161 C:197 45.0 0.29 G -136.6 31.3 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
 2016-02-24 VAL B:181 B:197 38.0 0.245 G -136.1 31.0 5.0 0.032 0.213 A:Q16531:0.213
 HOH
 5.279
 O
 O
VAL E:181 E:197 39.0 0.252 T -88.1 -46.5 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 VAL B:181 B:197 51.0 0.329 T -79.3 -7.4 5.0 0.032 0.297 A:None:0.297
 HOH
 5.341
 C
 O
VAL E:181 E:197 50.0 0.323 T -79.4 -7.3 NA NA NA
VAL H:181 H:197 52.0 0.335 T -79.7 -7.1 NA NA NA
VAL K:181 K:197 53.0 0.342 T -79.2 -7.2 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 VAL B:181 B:197 48.0 0.31 T -88.2 -18.3 12.0 0.077 0.233 A:Q16531:0.232
VAL E:181 E:197 46.0 0.297 T -87.9 -17.8 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
 2021-06-02 VAL B:151 B:197 46.0 0.297 T -112.7 -21.0 5.0 0.032 0.265 A:Q16531:0.265
VAL E:151 E:197 48.0 0.31 T -111.3 -25.6 NA NA NA
VAL H:151 H:197 46.0 0.297 T -115.5 -27.3 NA NA NA
VAL K:151 K:197 44.0 0.284 T -115.8 -27.4 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
 2014-08-06 VAL B:150 C:197 48.0 0.31 T -112.7 1.9 4.0 0.026 0.284 A:Q16531:0.284
 HOH
 8.982
 C
 O
4ci1 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 VAL B:222 B:198 48.0 0.31 T -56.8 -36.5 1.0 0.006 0.304 A:Q16531:0.303
 HOH
 4.209
 O
 O
4ci2 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 VAL B:222 B:198 47.0 0.303 T -65.9 -27.8 2.0 0.013 0.29 A:Q16531:0.29
 HOH
 6.445
 O
 O
4ci3 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 VAL B:222 B:198 48.0 0.31 T -55.3 -36.3 1.0 0.006 0.304 A:Q16531:0.303

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 VAL A:197 A:197 35.0 0.226 T -122.9 2.6