Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3214554 . G A CCDS2562.1:NM_016302.3:c.433Cga>Tga_NP_057386.2:p.145R>* Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:166 B:145 69.0 0.307 E -157.4 111.7 69.0 0.307 0.0
6bn8 2 Q96SW2 97.06 0.0 X-RAY
2018-06-06 ARG B:166 B:145 59.0 0.262 E -160.6 109.2 59.0 0.262 0.0
6bn9 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:166 B:145 60.0 0.267 E -156.4 107.5 60.0 0.267 0.0
6bnb 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:166 B:145 100.0 0.444 E -141.9 127.5 100.0 0.444 0.0
6boy 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:166 B:145 55.0 0.244 E -160.1 113.3 55.0 0.244 0.0
5hxb 3 Q96SW2 99.75 0.0 X-RAY
2016-06-29 ARG C:109 Z:145 59.0 0.262 E -149.9 142.2 59.0 0.262 0.0
ARG E:109 C:145 62.0 0.276 E -128.0 137.1 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
2017-05-03 ARG B:109 C:145 50.0 0.222 E -147.7 115.5 50.0 0.222 0.0 8W7
9.796
NH1
C22
6uml 2 Q96SW2 99.75 0.0 X-RAY
2020-04-15 ARG B:109 C:145 51.0 NA E -131.6 138.7 51.0 NA NA
6xk9 3 Q96SW2 99.75 0.0 X-RAY
2020-12-02 ARG C:109 Z:145 99.0 0.44 E -155.9 124.1 99.0 0.44 0.0
ARG F:109 C:145 99.0 0.44 E -154.4 123.2 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
2016-02-24 ARG B:129 B:145 81.0 0.36 E -153.8 125.1 81.0 0.36 0.0 HOH
3.115
CD
O
ARG E:129 E:145 80.0 0.356 E -154.8 125.4 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
2018-11-07 ARG B:129 B:145 172.0 0.764 E -158.9 129.8 172.0 0.764 0.0
ARG E:129 E:145 174.0 0.773 E -158.7 129.7 NA NA NA
ARG H:129 H:145 170.0 0.756 E -158.5 129.3 NA NA NA
ARG K:129 K:145 175.0 0.778 E -159.1 128.9 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
2018-11-07 ARG B:129 B:145 53.0 0.236 E -161.5 125.8 53.0 0.236 0.0
ARG E:129 E:145 54.0 0.24 E -160.4 126.2 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
2021-06-02 ARG B:99 B:145 94.0 0.418 E -157.6 120.7 94.0 0.418 0.0
ARG E:99 E:145 93.0 0.413 E -157.4 120.7 NA NA NA
ARG H:99 H:145 94.0 0.418 E -157.2 120.3 NA NA NA
ARG K:99 K:145 91.0 0.404 E -156.9 120.1 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
2014-08-06 ARG B:98 C:145 57.0 0.253 E -129.1 138.1 57.0 0.253 0.0
4ci1 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ARG B:170 B:146 79.0 0.351 E -152.1 124.4 79.0 0.351 0.0
4ci2 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ARG B:170 B:146 80.0 0.356 E -156.1 127.6 80.0 0.356 0.0
4ci3 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ARG B:170 B:146 77.0 0.342 E -153.5 126.6 77.0 0.342 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 ARG A:145 A:145 78.0 0.347 E -147.8 137.5