Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3215788 . C A CCDS2562.1:NM_016302.3:c.332cGg>cTg_NP_057386.2:p.111R>L Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:132 B:111 67.0 0.298 H -63.3 -44.2 67.0 0.298 0.0
6bn8 2 Q96SW2 97.06 0.0 X-RAY
2018-06-06 ARG B:132 B:111 73.0 0.324 H -63.7 -34.3 73.0 0.324 0.0
6bn9 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:132 B:111 71.0 0.316 H -61.0 -45.5 71.0 0.316 0.0
6bnb 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:132 B:111 84.0 0.373 H -60.9 -27.9 84.0 0.373 0.0
6boy 2 Q96SW2 97.06 0.0 X-RAY
2018-05-30 ARG B:132 B:111 66.0 0.293 H -62.6 -45.7 66.0 0.293 0.0
5hxb 3 Q96SW2 99.75 0.0 X-RAY
2016-06-29 ARG C:75 Z:111 72.0 0.32 H -49.7 -42.8 72.0 0.32 0.0
ARG E:75 C:111 79.0 0.351 H -49.6 -42.8 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
2017-05-03 ARG B:75 C:111 92.0 0.409 H -45.8 -39.0 92.0 0.409 0.0
6uml 2 Q96SW2 99.75 0.0 X-RAY
2020-04-15 ARG B:75 C:111 36.0 NA H -51.4 -42.5 36.0 NA NA
6xk9 3 Q96SW2 99.75 0.0 X-RAY
2020-12-02 ARG C:75 Z:111 78.0 0.347 H -56.7 -40.5 78.0 0.347 0.0
ARG F:75 C:111 77.0 0.342 H -57.0 -40.8 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
2016-02-24 ARG B:95 B:111 81.0 0.36 H -57.2 -40.1 81.0 0.36 0.0
ARG E:95 E:111 115.0 0.511 H -56.7 -40.1 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
2018-11-07 ARG B:95 B:111 106.0 0.471 H -59.4 -35.0 106.0 0.471 0.0
ARG E:95 E:111 125.0 0.556 H -58.8 -34.9 NA NA NA
ARG H:95 H:111 111.0 0.493 H -59.4 -34.6 NA NA NA
ARG K:95 K:111 105.0 0.467 H -59.3 -34.7 NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
2018-11-07 ARG B:95 B:111 94.0 0.418 H -59.6 -43.8 94.0 0.418 0.0
ARG E:95 E:111 91.0 0.404 H -59.6 -44.0 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
2021-06-02 ARG B:65 B:111 83.0 0.369 H -62.1 -40.4 83.0 0.369 0.0
ARG E:65 E:111 79.0 0.351 H -61.9 -40.5 NA NA NA
ARG H:65 H:111 81.0 0.36 H -62.2 -40.1 NA NA NA
ARG K:65 K:111 83.0 0.369 H -62.3 -40.0 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
2014-08-06 ARG B:64 C:111 93.0 0.413 H -48.8 -43.9 93.0 0.413 0.0
4ci1 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ARG B:136 B:112 49.0 0.218 H -57.4 -40.1 49.0 0.218 0.0 HOH
6.553
NH2
O
4ci2 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ARG B:136 B:112 47.0 0.209 H -59.9 -40.6 47.0 0.209 0.0
4ci3 2 P0CF65 84.08 0.0 X-RAY
2014-07-16 ARG B:136 B:112 49.0 0.218 H -57.9 -35.9 49.0 0.218 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 ARG A:111 A:111 69.0 0.307 H -55.4 -39.3