Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 3215942 . G A CCDS2562.1:NM_016302.3:c.178Cta>Tta_NP_057386.2:p.60L>L Homo sapiens cereblon (CRBN), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bn7 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 LEU B:81 B:60 1.0 0.006 G -81.9 8.0 1.0 0.006 0.0 RN3
 8.862
 CD2
 O3
6bn8 2 Q96SW2 97.06 0.0 X-RAY
 2018-06-06 LEU B:81 B:60 1.0 0.006 S -95.0 49.4 1.0 0.006 0.0
6bn9 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 LEU B:81 B:60 1.0 0.006 S -96.4 56.4 1.0 0.006 0.0
6bnb 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 LEU B:81 NA:NA DO NA DO DO DO NA NA NA
6boy 2 Q96SW2 97.06 0.0 X-RAY
 2018-05-30 LEU B:81 B:60 2.0 0.012 G -88.7 22.6 2.0 0.012 0.0 RN6
 8.775
 CD2
 O2
5hxb 3 Q96SW2 99.75 0.0 X-RAY
 2016-06-29 LEU C:24 Z:60 1.0 0.006 G -94.2 -14.2 1.0 0.006 0.0 85C
 9.165
 CD2
 O2
LEU E:24 C:60 1.0 0.006 G -94.6 -13.4 NA NA NA
5v3o 2 Q96SW2 99.75 0.0 X-RAY
 2017-05-03 LEU B:24 C:60 2.0 0.012 G -82.1 -7.5 2.0 0.012 0.0 8W7
 8.758
 CD2
 O2
6uml 2 Q96SW2 99.75 0.0 X-RAY
 2020-04-15 LEU B:24 C:60 59.0 0.347 -95.2 360.0 59.0 0.347 0.0 Y70
 8.971
 CG
 O19
6xk9 3 Q96SW2 99.75 0.0 X-RAY
 2020-12-02 LEU C:24 Z:60 8.0 0.047 G -74.8 -9.2 8.0 0.047 0.0 V4M
 8.657
 CD2
 O2
LEU F:24 C:60 10.0 0.059 G -74.8 -9.4 NA NA NA
5fqd 2 Q96SW2 99.02 0.0 X-RAY
 2016-02-24 LEU B:44 B:60 5.0 0.029 G -76.2 -10.1 5.0 0.029 0.0 LVY
HOH
 8.717
3.012
 CD2
O
 O18
O
LEU E:44 E:60 5.0 0.029 G -76.0 -9.4 NA NA NA
6h0f 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 LEU B:44 NA:NA DO NA DO DO DO NA NA NA
LEU E:44 NA:NA DO NA DO DO DO NA NA NA
LEU H:44 NA:NA DO NA DO DO DO NA NA NA
LEU K:44 NA:NA DO NA DO DO DO NA NA NA
6h0g 2 Q96SW2 99.02 0.0 X-RAY
 2018-11-07 LEU B:44 B:60 1.0 0.006 G -83.9 -10.8 1.0 0.006 0.0 Y70
 7.581
 HD23
 O19
LEU E:44 E:60 4.0 0.024 G -77.8 -8.9 NA NA NA
7lps 2 Q96SW2 100.0 0.0 X-RAY
 2021-06-02 LEU B:14 B:60 3.0 0.018 G -77.3 -9.9 3.0 0.018 0.0 RN9
 8.580
 CD2
 O2
LEU E:14 E:60 3.0 0.018 G -76.7 -9.9 NA NA NA
LEU H:14 H:60 4.0 0.024 G -77.0 -10.0 NA NA NA
LEU K:14 K:60 3.0 0.018 G -76.5 -10.1 NA NA NA
4tz4 2 Q96SW2 100.0 0.0 X-RAY
 2014-08-06 LEU B:13 C:60 2.0 0.012 G -95.8 -11.2 2.0 0.012 0.0 LVY
 9.270
 N
 O18
4ci1 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 LEU B:85 B:61 1.0 0.006 G -74.5 -12.4 1.0 0.006 0.0 EF2
 8.964
 N
 O01
4ci2 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 LEU B:85 B:61 2.0 0.012 G -74.3 -14.5 2.0 0.012 0.0 LVY
 8.922
 N
 O18
4ci3 2 P0CF65 84.08 0.0 X-RAY
 2014-07-16 LEU B:85 B:61 0.0 0.0 G -73.5 -12.9 0.0 0.0 0.0 Y70
 8.853
 CD1
 O19

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q96sw2-f1 1 Q96SW2 100.0 0.0 LEU A:60 A:60 1.0 0.006 G -81.2 -7.3