Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 41267257 . A C CCDS2694.1:NM_001098209.1:c.841Aaa>Caa_NP_001091679.1:p.281K>Q Homo sapiens catenin beta 1 (CTNNB1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2z6g 1 Q90424 97.06 0.0 X-RAY
 2008-02-12 LYS A:280 A:280 79.0 0.395 H -53.4 -33.0 79.0 0.395 0.0
2z6h 1 P35222 100.0 0.0 X-RAY
 2008-02-12 LYS A:144 A:281 82.0 0.41 H -78.7 -35.9 82.0 0.41 0.0
2gl7 1 P35222 99.82 0.0 X-RAY
 2006-10-31 LYS A:145 A:281 82.0 0.41 H -62.1 -40.9 82.0 0.41 0.0 HOH
 3.293
 O
 O
LYS D:145 D:281 79.0 0.395 H -73.3 -31.9 NA NA NA
1i7w 1 Q02248 100.0 0.0 X-RAY
 2001-05-09 LYS A:148 A:281 70.0 0.35 H -66.4 -45.9 70.0 0.35 0.0 HOH
 2.637
 NZ
 O
LYS C:148 C:281 70.0 0.35 H -70.9 -41.0 70.0 0.35 0.0 HOH
 3.635
 NZ
 O
1i7x 1 Q02248 100.0 0.0 X-RAY
 2001-05-16 LYS A:148 A:281 80.0 0.4 H -62.5 -32.6 65.0 0.325 0.075 C:Q02248:0.075
LYS C:148 C:281 92.0 0.46 H -58.4 -47.8 92.0 0.46 0.0
1jpp 1 Q02248 100.0 0.0 X-RAY
 2002-01-16 LYS A:148 A:281 72.0 0.36 H -74.9 -51.4 72.0 0.36 0.0 HOH
 7.204
 O
 O
LYS B:148 B:281 69.0 0.345 H -63.2 -54.0 NA NA NA
1m1e 1 Q02248 100.0 0.0 X-RAY
 2002-10-16 LYS A:148 A:281 91.0 0.455 H -65.9 -45.3 91.0 0.455 0.0 HOH
 2.872
 O
 O
1v18 1 Q02248 100.0 0.0 X-RAY
 2005-01-12 LYS A:148 A:281 74.0 0.37 H -66.0 -41.2 74.0 0.37 0.0 HOH
 3.388
 O
 O
4ev8 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 LYS A:148 A:281 91.0 0.455 H -66.1 -40.1 91.0 0.455 0.0 URE
URE
URE
HOH
 6.018
6.774
7.470
2.797
 CD
NZ
N
O
 N1
N1
N2
O
4ev9 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 LYS A:148 A:281 88.0 0.44 H -66.0 -44.2 88.0 0.44 0.0 URE
URE
HOH
 5.921
5.906
3.173
 O
NZ
O
 N1
N1
O
4eva 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 LYS A:148 A:281 90.0 0.45 H -63.7 -44.6 90.0 0.45 0.0 URE
HOH
 6.298
3.839
 CD
NZ
 N1
O
LYS B:148 C:281 90.0 0.45 H -64.7 -41.8 NA NA NA
4evp 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 LYS A:148 A:281 80.0 0.4 H -71.0 -39.7 80.0 0.4 0.0 HOH
 4.860
 N
 O
4evt 1 Q02248 100.0 0.0 X-RAY
 2013-05-01 LYS A:148 A:281 82.0 0.41 H -61.4 -44.2 82.0 0.41 0.0 URE
URE
URE
HOH
 6.704
5.789
9.230
4.656
 O
CD
CE
N
 N1
N2
N1
O
3ouw 1 Q02248 100.0 0.0 X-RAY
 2010-11-24 LYS A:150 A:281 71.0 0.355 H -74.9 -57.0 71.0 0.355 0.0
3oux 1 Q02248 100.0 0.0 X-RAY
 2010-11-24 LYS A:150 A:281 98.0 0.49 H -63.9 -58.8 98.0 0.49 0.0 HOH
 6.241
 N
 O
1jpw 1 P35222 99.63 0.0 X-RAY
 2001-12-05 LYS A:151 A:281 83.0 0.415 H -65.4 -47.7 83.0 0.415 0.0 HOH
 3.619
 CG
 O
LYS C:151 B:281 67.0 0.335 H -57.2 -53.4 NA NA NA
LYS E:151 C:281 65.0 0.325 H -60.9 -50.0 NA NA NA
1qz7 1 P35222 100.0 0.0 X-RAY
 2003-11-18 LYS A:149 A:281 68.0 0.34 H -64.1 -52.4 68.0 0.34 0.0
7ar4 1 P35222 99.63 0.0 X-RAY
 2021-04-07 LYS A:152 AAA:281 80.0 0.4 H -61.4 -44.9 80.0 0.4 0.0 HOH
 7.915
 HE3
 O
1g3j 1 P35222 100.0 0.0 X-RAY
 2000-12-11 LYS A:149 A:281 80.0 0.4 H -64.9 -40.8 80.0 0.4 0.0 HOH
 4.180
 CG
 O
LYS C:149 C:281 29.0 NA H -66.7 -43.5 NA NA NA
1th1 1 P35222 100.0 0.0 X-RAY
 2004-09-07 LYS A:149 A:281 73.0 0.365 H -66.2 -40.6 73.0 0.365 0.0 HOH
 5.627
 N
 O
LYS B:149 B:281 86.0 0.43 H -76.7 -38.9 NA NA NA
1jdh 1 P35222 100.0 0.0 X-RAY
 2001-12-05 LYS A:147 A:281 83.0 0.415 H -63.6 -44.4 83.0 0.415 0.0 HOH
 3.058
 NZ
 O
3tx7 1 P35222 100.0 0.0 X-RAY
 2011-12-14 LYS A:145 A:281 60.0 0.3 H -62.8 -43.2 60.0 0.3 0.0
1t08 1 P35222 100.0 0.0 X-RAY
 2004-10-12 LYS A:136 A:281 92.0 0.46 H -66.6 -44.4 92.0 0.46 0.0 HOH
 2.953
 O
 O
4djs 1 P35222 100.0 0.0 X-RAY
 2012-10-17 LYS A:134 A:281 64.0 0.32 H -64.7 -37.0 64.0 0.32 0.0
2bct 1 Q02248 100.0 0.0 X-RAY
 1997-10-15 LYS A:132 A:281 69.0 0.345 H -51.0 -45.6 69.0 0.345 0.0
1luj 1 P35222 100.0 0.0 X-RAY
 2002-10-16 LYS A:132 A:281 85.0 0.425 H -67.2 -43.7 85.0 0.425 0.0
3bct 1 Q02248 100.0 0.0 X-RAY
 1997-11-19 LYS A:89 A:281 84.0 0.42 H -62.8 -38.7 84.0 0.42 0.0 HOH
 3.121
 O
 O
3sla 1 P35222 100.0 1e-112 X-RAY
 2012-02-29 LYS A:143 A:281 80.0 0.4 H -53.7 -38.6 80.0 0.4 0.0 GOL
 6.644
 NZ
 O1
LYS B:143 B:281 82.0 0.41 H -50.4 -46.9 NA NA NA
LYS C:143 C:281 83.0 0.415 H -71.2 -34.8 NA NA NA
LYS D:143 D:281 79.0 0.395 H -63.5 -46.1 NA NA NA
LYS E:143 E:281 64.0 0.32 H -63.2 -38.0 NA NA NA
3sl9 1 P35222 100.0 2e-111 X-RAY
 2012-02-29 LYS A:143 A:281 84.0 0.42 H -64.1 -39.2 84.0 0.42 0.0 EDO
HOH
 8.804
2.908
 N
O
 O1
O
LYS C:143 B:281 75.0 0.375 H -64.3 -34.8 NA NA NA
LYS E:143 E:281 76.0 0.38 H -62.0 -38.2 NA NA NA
LYS G:143 G:281 93.0 0.465 H -61.3 -37.6 NA NA NA
7afw 1 P35222 100.0 2e-111 X-RAY
 2020-12-16 LYS A:143 A:281 81.0 0.405 H -61.8 -44.8 81.0 0.405 0.0 R9Q
HOH
 6.426
2.747
 NZ
NZ
 C5
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p35222-f1 1 P35222 100.0 0.0 LYS A:281 A:281 80.0 0.4 H -67.6 -40.5