Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 48884945 . G A CCDS2778.1:NM_004157.2:c.85Ctc>Ttc_NP_004148.1:p.29L>F Homo sapiens protein kinase cAMP-dependent type II regulatory subunit alpha (PRKAR2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3j4q 2 Q8K1M3 87.13 0.0 EM
 2013-11-13 LEU B:29 B:29 92.0 0.541 H -64.0 -33.2 41.0 0.241 0.3 C:Q8K1M3:0.3
LEU C:29 C:29 98.0 0.576 H -64.4 -40.1 37.0 0.218 0.358 B:Q8K1M3:0.359
3j4r 2 Q8K1M3 87.13 0.0 EM
 2013-11-13 LEU B:29 B:29 90.0 0.529 H -64.0 -33.3 38.0 0.224 0.305 C:Q8K1M3:0.306
LEU C:29 C:29 92.0 0.541 H -64.6 -32.8 39.0 0.229 0.312 B:Q8K1M3:0.312
2kyg 1 P13861 100.0 3e-24 NMR
 2010-10-20 LEU A:34 A:28 121.0 0.712 H -92.4 -43.8 30.0 0.176 0.536 B:P13861:0.535
LEU B:34 B:28 107.0 0.629 H -73.1 -44.2 35.0 0.206 0.423 A:P13861:0.424
2hwn 1 P12368 97.73 7e-23 X-RAY
 2006-11-21 LEU A:29 A:28 97.0 0.571 H -64.1 -40.6 23.0 0.135 0.436 B:P12368:0.435
 HOH
 2.841
 N
 O
LEU B:29 B:28 90.0 0.529 H -67.9 -34.8 16.0 0.094 0.435 A:P12368:0.435
 HOH
 2.947
 N
 O
LEU C:29 C:28 98.0 0.576 H -64.9 -40.3 NA NA NA
LEU D:29 D:28 93.0 0.547 H -70.3 -37.0 NA NA NA
4zp3 1 P13861 100.0 1e-22 X-RAY
 2016-05-04 LEU A:28 A:28 91.0 0.535 H -67.0 -32.8 19.0 0.112 0.423 B:P13861:0.424
 HOH
 5.238
 N
 O
LEU B:28 B:28 91.0 0.535 H -71.6 -31.2 24.0 0.141 0.394 A:P13861:0.394
 HOH
 4.102
 CD2
 O
LEU C:28 C:28 92.0 0.541 H -73.7 -36.3 NA NA NA
LEU D:28 D:28 95.0 0.559 H -63.1 -37.2 NA NA NA
LEU E:28 E:28 90.0 0.529 H -67.4 -33.4 NA NA NA
LEU F:28 F:28 91.0 0.535 H -67.9 -29.1 NA NA NA
LEU G:28 G:28 93.0 0.547 H -61.0 -20.1 NA NA NA
LEU H:28 H:28 92.0 0.541 H -66.8 -27.2 NA NA NA
LEU I:28 I:28 95.0 0.559 H -74.3 -40.6 NA NA NA
LEU J:28 J:28 93.0 0.547 H -67.1 -34.3 NA NA NA
LEU K:28 K:28 90.0 0.529 H -71.9 -26.3 NA NA NA
LEU L:28 L:28 93.0 0.547 H -74.9 -37.3 NA NA NA
3tmh 2 P12368 95.45 3e-22 X-RAY
 2012-09-05 LEU B:32 B:28 76.0 0.447 -110.5 -58.6 42.0 0.247 0.2 C:P12368:0.2
LEU C:32 C:28 74.0 0.435 S -110.7 -58.8 60.0 0.353 0.082 B:P12368:0.082
LEU F:32 F:28 76.0 0.447 S -110.1 -59.0 58.0 0.341 0.106 G:P12368:0.106
LEU G:32 G:28 74.0 0.435 S -106.0 -43.2 59.0 0.347 0.088 F:P12368:0.088
2izy 1 P12368 95.45 4e-22 X-RAY
 2006-11-13 LEU A:29 A:30 98.0 0.576 H -68.6 -37.0 20.0 0.118 0.458 F:P12368:0.118
B:P12368:0.424
 HOH
 3.068
 N
 O
LEU B:29 B:30 96.0 0.565 H -67.1 -35.3 19.0 0.112 0.453 D:P12368:0.112
A:P12368:0.394
 HOH
 3.147
 N
 O
LEU C:29 C:30 95.0 0.559 H -68.2 -32.2 20.0 0.118 0.441 D:P12368:0.406
A:P12368:0.106
 HOH
 2.817
 N
 O
LEU D:29 D:30 100.0 0.588 H -63.8 -34.9 29.0 0.171 0.417 C:P12368:0.418
 HOH
 3.401
 N
 O
LEU E:29 E:30 96.0 0.565 H -64.3 -41.6 22.0 0.129 0.436 F:P12368:0.388
B:P12368:0.106
 HOH
 2.823
 N
 O
LEU F:29 F:30 95.0 0.559 H -63.3 -37.9 19.0 0.112 0.447 H:P12368:0.1
E:P12368:0.406
 HOH
 3.079
 N
 O
LEU G:29 G:30 98.0 0.576 H -65.8 -39.2 23.0 0.135 0.441 H:P12368:0.388
E:P12368:0.106
 HOH
 3.014
 N
 O
LEU H:29 H:30 98.0 0.576 H -58.6 -37.8 26.0 0.153 0.423 G:P12368:0.424
 HOH
 2.926
 N
 O
5h78 1 P13861 93.02 3e-21 X-RAY
 2017-06-28 LEU A:29 A:28 93.0 0.547 H -70.9 -27.7 23.0 0.135 0.412 B:P13861:0.412
 HOH
 3.091
 N
 O
LEU B:29 B:28 89.0 0.524 H -72.7 -28.9 20.0 0.118 0.406 A:P13861:0.406
 HOH
 3.181
 N
 O
2izx 1 P13861 100.0 1e-20 X-RAY
 2006-11-08 LEU A:26 A:28 91.0 0.535 H -64.6 -32.7 19.0 0.112 0.423 B:P13861:0.424
 DTD
HOH
 8.642
2.872
 O
N
 S4
O
LEU B:26 B:28 91.0 0.535 H -64.0 -33.2 20.0 0.118 0.417 A:P13861:0.418
 HOH
 2.910
 N
 O
5xby 1 P13861,P38507 95.35 2e-20 X-RAY
 2017-07-05 LEU A:29 A:28 99.0 0.582 H -55.4 -36.7 28.0 0.165 0.417 B:P13861+P38507:0.418
LEU B:29 B:28 100.0 0.588 H -61.1 -35.4 28.0 0.165 0.423 A:P13861+P38507:0.424
LEU C:29 C:28 96.0 0.565 H -62.0 -35.6 NA NA NA
LEU D:29 D:28 98.0 0.576 H -62.1 -35.9 NA NA NA
5h77 1 P13861,P38507 83.67 7e-20 X-RAY
 2017-06-28 LEU A:29 A:26 97.0 0.571 H -70.5 -31.9 27.0 0.159 0.412 B:P13861+P38507:0.412
LEU B:29 B:26 95.0 0.559 H -72.2 -31.7 23.0 0.135 0.424 A:P13861+P38507:0.424
LEU C:29 C:26 93.0 0.547 H -72.1 -30.9 NA NA NA
LEU D:29 D:26 97.0 0.571 H -73.8 -30.9 NA NA NA
LEU E:29 E:26 99.0 0.582 H -73.5 -32.2 NA NA NA
LEU F:29 F:26 95.0 0.559 H -71.5 -31.9 NA NA NA
LEU G:29 G:26 89.0 0.524 H -74.8 -30.9 NA NA NA
LEU H:29 H:26 93.0 0.547 H -72.6 -30.5 NA NA NA
LEU I:29 I:26 96.0 0.565 H -72.4 -32.1 NA NA NA
LEU J:29 J:26 96.0 0.565 H -72.6 -31.3 NA NA NA
LEU K:29 K:26 97.0 0.571 H -72.3 -29.0 NA NA NA
LEU L:29 L:26 94.0 0.553 H -73.4 -31.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13861-f1 1 P13861 100.0 0.0 LEU A:29 A:29 95.0 0.559 H -74.9 -27.5