Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 48884955 . C A CCDS2778.1:NM_004157.2:c.75caG>caT_NP_004148.1:p.25Q>H Homo sapiens protein kinase cAMP-dependent type II regulatory subunit alpha (PRKAR2A), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3j4q 2 Q8K1M3 87.13 0.0 EM
 2013-11-13 GLN B:25 B:25 161.0 0.894 51.0 51.8 161.0 0.894 0.0
GLN C:25 C:25 143.0 0.794 49.5 51.9 143.0 0.794 0.0
3j4r 2 Q8K1M3 87.13 0.0 EM
 2013-11-13 GLN B:25 B:25 160.0 0.889 51.0 51.8 160.0 0.889 0.0
GLN C:25 C:25 142.0 0.789 49.5 51.9 142.0 0.789 0.0
2kyg 1 P13861 100.0 3e-24 NMR
 2010-10-20 GLN A:30 A:24 156.0 0.867 56.3 71.2 102.0 0.567 0.3 B:P13861:0.3
GLN B:30 B:24 129.0 0.717 57.7 86.0 93.0 0.517 0.2 A:P13861:0.2
2hwn 1 P12368 97.73 7e-23 X-RAY
 2006-11-21 GLN A:25 A:24 165.0 0.917 52.6 62.1 98.0 0.544 0.373 B:P12368:0.372
 HOH
 2.701
 NE2
 O
GLN B:25 B:24 159.0 0.883 52.9 63.5 159.0 0.883 0.0 GOL
HOH
 8.669
2.666
 C
O
 C3
O
GLN C:25 C:24 139.0 0.772 49.5 57.8 NA NA NA
GLN D:25 D:24 158.0 0.878 52.8 63.9 NA NA NA
4zp3 1 P13861 100.0 1e-22 X-RAY
 2016-05-04 GLN A:24 A:24 140.0 0.778 47.8 68.7 115.0 0.639 0.139 B:P13861:0.139
 HOH
 2.679
 NE2
 O
GLN B:24 B:24 161.0 0.894 44.7 64.9 154.0 0.856 0.038 M:O43687:0.039
 HOH
 3.591
 CG
 O
GLN C:24 C:24 141.0 0.783 39.1 60.8 NA NA NA
GLN D:24 D:24 166.0 0.922 39.8 63.7 NA NA NA
GLN E:24 E:24 143.0 0.794 37.7 65.9 NA NA NA
GLN F:24 F:24 162.0 0.9 42.9 67.7 NA NA NA
GLN G:24 G:24 136.0 0.756 42.1 58.5 NA NA NA
GLN H:24 H:24 153.0 0.85 39.0 59.0 NA NA NA
GLN I:24 I:24 144.0 0.8 51.8 66.6 NA NA NA
GLN J:24 J:24 157.0 0.872 36.2 62.0 NA NA NA
GLN K:24 K:24 138.0 0.767 48.6 61.2 NA NA NA
GLN L:24 L:24 156.0 0.867 48.3 60.2 NA NA NA
3tmh 2 P12368 95.45 3e-22 X-RAY
 2012-09-05 GLN B:28 B:24 130.0 0.722 61.8 56.6 57.0 0.317 0.405 C:P12368:0.406
GLN C:28 C:24 127.0 0.706 60.6 57.3 127.0 0.706 0.0
GLN F:28 F:24 131.0 0.728 61.2 56.6 131.0 0.728 0.0
GLN G:28 G:24 130.0 0.722 54.5 61.2 124.0 0.689 0.033 F:P12368:0.033
2izy 1 P12368 95.45 4e-22 X-RAY
 2006-11-13 GLN A:25 A:26 162.0 0.9 46.6 60.9 162.0 0.9 0.0 HOH
 3.100
 OE1
 O
GLN B:25 B:26 164.0 0.911 46.1 60.7 164.0 0.911 0.0 HOH
 2.883
 O
 O
GLN C:25 C:26 158.0 0.878 44.9 57.9 158.0 0.878 0.0 HOH
 2.478
 O
 O
GLN D:25 D:26 159.0 0.883 41.7 68.2 159.0 0.883 0.0 HOH
 3.463
 CA
 O
GLN E:25 E:26 160.0 0.889 48.0 58.5 160.0 0.889 0.0 HOH
 3.436
 O
 O
GLN F:25 F:26 157.0 0.872 39.1 62.5 157.0 0.872 0.0 HOH
 3.013
 O
 O
GLN G:25 G:26 161.0 0.894 40.7 60.2 161.0 0.894 0.0 HOH
 2.673
 O
 O
GLN H:25 H:26 138.0 0.767 43.6 60.7 136.0 0.756 0.011 G:P12368:0.011
 HOH
 2.700
 NE2
 O
5h78 1 P13861 93.02 3e-21 X-RAY
 2017-06-28 GLN A:25 A:24 146.0 0.811 48.1 60.2 126.0 0.7 0.111 B:P13861:0.111
 HOH
 3.140
 O
 O
GLN B:25 B:24 162.0 0.9 46.5 60.5 161.0 0.894 0.006 A:P13861:0.006
 HOH
 3.402
 NE2
 O
2izx 1 P13861 100.0 1e-20 X-RAY
 2006-11-08 GLN A:22 A:24 142.0 0.789 49.5 51.9 63.0 0.35 0.439 B:P13861:0.439
 DTD
HOH
 8.568
2.733
 N
NE2
 O3
O
GLN B:22 B:24 161.0 0.894 51.1 51.7 160.0 0.889 0.005 A:P13861:0.006
 HOH
 2.752
 O
 O
5xby 1 P13861,P38507 95.35 2e-20 X-RAY
 2017-07-05 GLN A:25 A:24 139.0 0.772 43.2 60.0 54.0 0.3 0.472 B:P13861+P38507:0.472
GLN B:25 B:24 162.0 0.9 41.7 60.1 162.0 0.9 0.0
GLN C:25 C:24 138.0 0.767 44.4 59.8 NA NA NA
GLN D:25 D:24 163.0 0.906 44.4 60.3 NA NA NA
5h77 1 P13861,P38507 83.67 7e-20 X-RAY
 2017-06-28 GLN A:25 A:22 137.0 0.761 46.2 55.2 102.0 0.567 0.194 B:P13861+P38507:0.194
GLN B:25 B:22 162.0 0.9 48.4 53.8 162.0 0.9 0.0
GLN C:25 C:22 145.0 0.806 47.2 55.7 NA NA NA
GLN D:25 D:22 161.0 0.894 46.3 55.6 NA NA NA
GLN E:25 E:22 150.0 0.833 47.8 54.5 NA NA NA
GLN F:25 F:22 155.0 0.861 44.7 59.3 NA NA NA
GLN G:25 G:22 132.0 0.733 46.4 54.4 NA NA NA
GLN H:25 H:22 163.0 0.906 45.3 55.1 NA NA NA
GLN I:25 I:22 141.0 0.783 47.2 54.5 NA NA NA
GLN J:25 J:22 159.0 0.883 46.9 54.8 NA NA NA
GLN K:25 K:22 149.0 0.828 47.1 54.1 NA NA NA
GLN L:25 L:22 154.0 0.856 46.8 56.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13861-f1 1 P13861 100.0 0.0 GLN A:25 A:25 163.0 0.906 43.5 51.3