Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 48884963 . G A CCDS2778.1:NM_004157.2:c.67Cga>Tga_NP_004148.1:p.23R>* Homo sapiens protein kinase cAMP-dependent type II regulatory subunit alpha (PRKAR2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3j4q 2 Q8K1M3 87.13 0.0 EM
 2013-11-13 ARG B:23 B:23 174.0 0.773 H -72.1 -45.3 174.0 0.773 0.0
ARG C:23 C:23 179.0 0.796 H -69.6 -43.4 161.0 0.716 0.08 A:None:0.08
3j4r 2 Q8K1M3 87.13 0.0 EM
 2013-11-13 ARG B:23 B:23 173.0 0.769 H -72.0 -45.3 173.0 0.769 0.0
ARG C:23 C:23 181.0 0.804 H -69.5 -43.4 165.0 0.733 0.071 A:None:0.071
2kyg 1 P13861 100.0 3e-24 NMR
 2010-10-20 ARG A:28 A:22 192.0 0.853 H -50.6 -36.1 125.0 0.556 0.297 C:Q06455:0.298
ARG B:28 B:22 192.0 0.853 H -84.8 -22.8 92.0 0.409 0.444 C:Q06455:0.444
2hwn 1 P12368 97.73 7e-23 X-RAY
 2006-11-21 ARG A:23 A:22 167.0 0.742 H -74.7 -42.6 127.0 0.564 0.178 E:None:0.178
B:P12368:0.004
 HOH
 2.944
 O
 O
ARG B:23 B:22 168.0 0.747 H -90.1 -45.4 168.0 0.747 0.0 GOL
HOH
 9.039
2.878
 CG
NE
 O3
O
ARG C:23 C:22 170.0 0.756 H -71.8 -40.2 NA NA NA
ARG D:23 D:22 74.0 NA H -79.2 -57.9 NA NA NA
4zp3 1 P13861 100.0 1e-22 X-RAY
 2016-05-04 ARG A:22 A:22 181.0 0.804 H -65.0 -50.8 111.0 0.493 0.311 M:O43687:0.311
 HOH
 4.554
 CG
 O
ARG B:22 B:22 171.0 0.76 H -64.9 -49.6 96.0 0.427 0.333 M:O43687:0.333
 HOH
 5.409
 N
 O
ARG C:22 C:22 172.0 0.764 H -65.6 -56.8 NA NA NA
ARG D:22 D:22 176.0 0.782 H -62.1 -42.3 NA NA NA
ARG E:22 E:22 174.0 0.773 H -42.7 -60.8 NA NA NA
ARG F:22 F:22 173.0 0.769 H -59.3 -64.5 NA NA NA
ARG G:22 G:22 181.0 0.804 H -63.5 -51.4 NA NA NA
ARG H:22 H:22 170.0 0.756 H -56.1 -51.2 NA NA NA
ARG I:22 I:22 183.0 0.813 H -58.8 -53.2 NA NA NA
ARG J:22 J:22 172.0 0.764 H -70.5 -50.4 NA NA NA
ARG K:22 K:22 176.0 0.782 H -66.6 -57.3 NA NA NA
ARG L:22 L:22 168.0 0.747 H -68.6 -62.4 NA NA NA
3tmh 2 P12368 95.45 3e-22 X-RAY
 2012-09-05 ARG B:26 B:22 193.0 0.858 T -83.0 -3.0 190.0 0.844 0.014 D:O43572:0.013
ARG C:26 C:22 192.0 0.853 T -82.3 -2.7 192.0 0.853 0.0
ARG F:26 F:22 197.0 0.876 T -83.3 -3.3 197.0 0.876 0.0 HOH
 7.414
 NH2
 O
ARG G:26 G:22 194.0 0.862 T -75.1 -5.7 190.0 0.844 0.018 H:O43572:0.018
2izy 1 P12368 95.45 4e-22 X-RAY
 2006-11-13 ARG A:23 A:24 165.0 0.733 H -77.7 -47.2 100.0 0.444 0.289 D:P12368:0.289
 HOH
 2.920
 O
 O
ARG B:23 B:24 174.0 0.773 H -71.3 -48.6 97.0 0.431 0.342 F:P12368:0.342
 HOH
 3.196
 O
 O
ARG C:23 C:24 165.0 0.733 H -72.2 -50.4 165.0 0.733 0.0 HOH
 2.600
 NH2
 O
ARG D:23 D:24 173.0 0.769 H -72.3 -47.9 93.0 0.413 0.356 A:P12368:0.356
 HOH
 2.852
 CZ
 O
ARG E:23 E:24 168.0 0.747 H -72.8 -47.0 79.0 0.351 0.396 H:P12368:0.396
 HOH
 2.994
 O
 O
ARG F:23 F:24 199.0 0.884 H -73.8 -52.3 126.0 0.56 0.324 B:P12368:0.324
 HOH
 3.597
 N
 O
ARG G:23 G:24 200.0 0.889 H -74.1 -52.6 200.0 0.889 0.0 HOH
 2.577
 NH2
 O
ARG H:23 H:24 200.0 0.889 H -72.2 -49.4 152.0 0.676 0.213 E:P12368:0.213
 HOH
 2.717
 O
 O
5h78 1 P13861 93.02 3e-21 X-RAY
 2017-06-28 ARG A:23 A:22 177.0 0.787 H -70.5 -54.6 177.0 0.787 0.0 HOH
 3.131
 NH2
 O
ARG B:23 B:22 177.0 0.787 H -70.1 -54.4 177.0 0.787 0.0 HOH
 2.854
 NH2
 O
2izx 1 P13861 100.0 1e-20 X-RAY
 2006-11-08 ARG A:20 A:22 179.0 0.796 H -69.6 -43.5 132.0 0.587 0.209 C:None:0.209
 DTD
DTD
HOH
 8.238
7.135
2.807
 CB
NH1
O
 O2
O3
O
ARG B:20 B:22 175.0 0.778 H -72.1 -45.3 175.0 0.778 0.0 HOH
 2.963
 NE
 O
5xby 1 P13861,P38507 95.35 2e-20 X-RAY
 2017-07-05 ARG A:23 A:22 176.0 0.782 H -59.1 -47.3 159.0 0.707 0.075 B:P13861+P38507:0.076
ARG B:23 B:22 183.0 0.813 H -45.3 -55.3 183.0 0.813 0.0
ARG C:23 C:22 186.0 0.827 H -63.1 -49.9 NA NA NA
ARG D:23 D:22 177.0 0.787 H -62.3 -50.3 NA NA NA
5h77 1 P13861,P38507 83.67 7e-20 X-RAY
 2017-06-28 ARG A:23 A:20 191.0 0.849 H -68.1 -32.7 191.0 0.849 0.0
ARG B:23 B:20 184.0 0.818 H -65.9 -36.8 184.0 0.818 0.0
ARG C:23 C:20 190.0 0.844 H -68.8 -34.9 NA NA NA
ARG D:23 D:20 169.0 0.751 H -66.4 -35.5 NA NA NA
ARG E:23 E:20 188.0 0.836 H -68.5 -34.6 NA NA NA
ARG F:23 F:20 188.0 0.836 H -69.7 -36.9 NA NA NA
ARG G:23 G:20 183.0 0.813 H -68.4 -37.3 NA NA NA
ARG H:23 H:20 194.0 0.862 H -67.2 -38.1 NA NA NA
ARG I:23 I:20 191.0 0.849 H -66.3 -35.7 NA NA NA
ARG J:23 J:20 197.0 0.876 H -69.6 -32.5 NA NA NA
ARG K:23 K:20 197.0 0.876 H -68.8 -33.0 NA NA NA
ARG L:23 L:20 185.0 0.822 H -70.5 -36.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p13861-f1 1 P13861 100.0 0.0 ARG A:23 A:23 174.0 0.773 H -80.0 -44.4